Publications by authors named "Alison Shone"

Claim this Profile
R
Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis.
W David Hong, Peter D Gibbons, Suet C Leung, Richard Amewu, Paul A Stocks, Alison E Shone

J Med Chem· May 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A multisystem investigation of raltegravir association with intestinal tissue: implications for pre-exposure prophylaxis and eradication.
Darren M Moss, Paul Curley, Alison Shone, Marco Siccardi, Andrew Owen

J Antimicrob Chemother· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.
Gemma L Nixon, Chandrakala Pidathala, Alison E Shone, Thomas Antoine, Nicholas Fisher

Future Med Chem· September 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antimalarial pharmacology and therapeutics of atovaquone.
Gemma L Nixon, Darren M Moss, Alison E Shone, David G Lalloo, Nicholas Fisher

J Antimicrob Chemother· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Giancarlo A Biagini, Nicholas Fisher, Alison E Shone, Murad A Mubaraki, Abhishek Srivastava

Proc Natl Acad Sci U S A· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.
Raman Sharma, Alexandre S Lawrenson, Nicholas E Fisher, Ashley J Warman, Alison E Shone

J Med Chem· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
Chandrakala Pidathala, Richard Amewu, Bénédicte Pacorel, Gemma L Nixon, Peter Gibbons, Alison E Shone

J Med Chem· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
Suet C Leung, Peter Gibbons, Richard Amewu, Gemma L Nixon, Chandrakala Pidathala, Alison E Shone

J Med Chem· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.
Peter Gibbons, Edite Verissimo, Nuna C Araujo, Victoria Barton, Gemma L Nixon, Alison E Shone

J Med Chem· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Edinson Lucumi, Claire Darling, Hyunil Jo, Andrew D Napper, Rajesh Chandramohanadas, Alison E Shone

Antimicrob Agents Chemother· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
Paul M O'Neill, Richard K Amewu, Gemma L Nixon, Fatima Bousejra ElGarah, Mathirut Mungthin, Alison E Shone

Angew Chem Int Ed Engl· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates.
Nuna C P Araújo, Victoria Barton, Michael Jones, Paul A Stocks, Stephen A Ward, Alison E Shone

Bioorg Med Chem Lett· April 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
Paul M O'Neill, Alison E Shone, Deborah Stanford, Gemma Nixon, Eghbaleh Asadollahy

J Med Chem· April 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
Paul M O'Neill, B Kevin Park, Alison E Shone, James L Maggs, Phillip Roberts

J Med Chem· March 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
Gemma L Ellis, Richard Amewu, Sunil Sabbani, Paul A Stocks, Alison Shone

J Med Chem· April 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Probing the validity of the probe-to-bone test in the diagnosis of osteomyelitis of the foot in diabetes.
Alison Shone, Jaclyn Burnside, Susan Chipchase, Fran Game, William Jeffcoate

Diabetes Care· April 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis