Publications by authors named "Allan B Gamble"

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Bioorthogonal Click-to-Release of Branched Pro-Fluorophores.
Thomasin Brind, Aggie Lawer, Tobias Todd, Sushant Aryal, Sarah Hook, Allan B Gamble

Chemistry· July 2025

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Stimuli-Responsive Prodrug Linkers That Simultaneously Release Cargo and Neutralize In Situ Generated (Aza)Quinone Methides.
Veera V Shivaji R Edupuganti, Siddharth S Matikonda, Aggie Lawer, Jessica M Fairhall, Harrison M Lewin, Allan B Gamble

Chemistry· June 2025

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Covalent Isothiocyanate Inhibitors of Macrophage Migration Inhibitory Factor as Potential Colorectal Cancer Treatments.
Lohitha Putha, Liang K Kok, Matthias Fellner, Malcolm T Rutledge, Allan B Gamble

ChemMedChem· November 2024

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Bioactive atropisomers: Unraveling design strategies and synthetic routes for drug discovery.
Shuai-Jiang Liu, Qian Zhao, Xiao-Chen Liu, Allan B Gamble, Wei Huang

Med Res Rev· September 2024

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Site-Specific Antimicrobial Activity of a Dual-Responsive Ciprofloxacin Prodrug.
Catherine L Ross, Aggie Lawer, Kathleen J Sircombe, Daniel Pletzer, Allan B Gamble

J Med Chem· June 2024

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Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Cytochrome Oxidase.
Aggie Lawer, Chelsea Tyler, Kiel Hards, Laura M Keighley, Chen-Yi Cheung, Allan B Gamble

ACS Med Chem Lett· October 2022

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Development of a bioorthogonal fluorescence-based assay for assessing drug uptake and delivery in bacteria.
Jocelyn M F Ooi, Jessica M Fairhall, Benjamin Spangler, Daniel J W Chong, Brian Y Feng, Allan B Gamble

RSC Adv· May 2022

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Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment.
Veera V Shivaji R Edupuganti, Joel D A Tyndall D A Tyndall, Allan B Gamble

Recent Pat Anticancer Drug Discov· February 2022

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Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia.
Jimin Hwang, Natalie Strange, Rami Mazraani, Matthew J Phillips, Allan B Gamble

Eur J Med Chem· February 2022

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SMA-BmobaSNO: an intelligent photoresponsive nitric oxide releasing polymer for drug nanoencapsulation and targeted delivery.
Houman Alimoradi, Ansa Thomas, Daniel D B Lyth, Anita Barzegar-Fallah, Siddharth S Matikonda, Allan B Gamble

Nanotechnology· February 2022

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Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against : A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles.
Jimin Hwang, Sonya Mros, Allan B Gamble, Joel D A Tyndall, Arlene McDowell

Pharmaceutics· February 2022

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Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues.
Jimin Hwang, Natalie Strange, Matthew J A Phillips, Alexandra L Krause, Astra Heywood, Allan B Gamble

Eur J Med Chem· November 2021

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Hydrogen Sulfide-Responsive Bicontinuous Nanospheres.
Daniel A Paterson, Wye-Khay Fong, Sarah Hook, Allan B Gamble

Biomacromolecules· November 2021

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EGFR-targeted prodrug activation using bioorthogonal alkene-azide click-and-release chemistry.
Jessica M Fairhall, Júlia C Camilli, Blake H Gibson, Sarah Hook, Allan B Gamble

Bioorg Med Chem· September 2021

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Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and Analogues.
Michael P Badart, Emma M Barnes, Andrew P Cording, Selena C L Gilmer, Ian D Billinghurst, Allan B Gamble

ChemMedChem· April 2021

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Tuning activation and self-immolative properties of the bioorthogonal alkene-azide click-and-release strategy.
Jessica M Fairhall, Madoka Murayasu, Sumit Dadhwal, Sarah Hook, Allan B Gamble

Org Biomol Chem· July 2020

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Tetrafluoroaryl azide as an N-terminal capping group for click-to-dissolve diphenylalanine hydrogels.
Sumit Dadhwal, Jessica M Fairhall, Sarah Hook, Allan B Gamble

RSC Adv· March 2020

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Controlled Delivery of Nitric Oxide for Cancer Therapy.
Houman Alimoradi, Khaled Greish, Allan B Gamble, Gregory I Giles

Pharm Nanotechnol· January 2020

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Structure-activity analysis of peptidic Chlamydia HtrA inhibitors.
Ayodeji A Agbowuro, Jimin Hwang, Emma Peel, Rami Mazraani, Alexandra Springwald, Allan B Gamble

Bioorg Med Chem· September 2019

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Alkene-Azide 1,3-Dipolar Cycloaddition as a Trigger for Ultrashort Peptide Hydrogel Dissolution.
Sumit Dadhwal, Jessica M Fairhall, Shailesh K Goswami, Sarah Hook, Allan B Gamble

Chem Asian J· April 2019

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Proteases and protease inhibitors in infectious diseases.
Ayodeji A Agbowuro, Wilhelmina M Huston, Allan B Gamble, Joel D A Tyndall

Med Res Rev· July 2018

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Poloxamer 407-chitosan grafted thermoresponsive hydrogels achieve synchronous and sustained release of antigen and adjuvant from single-shot vaccines.
Sharan Bobbala, Blake Gibson, Allan B Gamble, Arlene McDowell, Sarah Hook

Immunol Cell Biol· July 2018

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Honey reduces the metastatic characteristics of prostate cancer cell lines by promoting a loss of adhesion.
Sean D A Abel, Sumit Dadhwal, Allan B Gamble, Sarah K Baird

PeerJ· July 2018

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Mechanistic Evaluation of Bioorthogonal Decaging with trans-Cyclooctene: The Effect of Fluorine Substituents on Aryl Azide Reactivity and Decaging from the 1,2,3-Triazoline.
Siddharth S Matikonda, Jessica M Fairhall, Franziska Fiedler, Suchaya Sanhajariya, Robert A J Tucker, Allan B Gamble

Bioconjug Chem· February 2018

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Detection of Biosynthetic Precursors, Discovery of Glycosylated Forms, and Homeostasis of Calcitonin in Human Cancer Cells.
Feihua Cao, Allan B Gamble, Hideki Onagi, Joanna Howes, James E Hennessy

Anal Chem· July 2017

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