Publications by authors named "Joel D A Tyndall"

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The molecular basis of intrinsic resistance to azoles in .
Michaela Lackner, Stephanie Toepfer, Mikhail V Keniya, Carlos Lax, Francisco E Nicolas, Joel D A Tyndall

Antimicrob Agents Chemother· December 2025

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A pilot study of re-purposing drugs to treat koalas with chlamydia.
Charlotte Fleming, Hannah Nugent, Susel Loli Quinteros, Bentotage S M Fernando, Joel D A Tyndall

Sci Rep· November 2025

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Stimuli-Responsive Prodrug Linkers That Simultaneously Release Cargo and Neutralize In Situ Generated (Aza)Quinone Methides.
Veera V Shivaji R Edupuganti, Siddharth S Matikonda, Aggie Lawer, Jessica M Fairhall, Harrison M Lewin, Joel D A Tyndall

Chemistry· June 2025

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Exploring Long Arm Amide-Linked Side Chains in the Design of Antifungal Azole Inhibitors of Sterol 14α-Demethylase (CYP51).
Marwa Alsulaimany, Mikhail V Keniya, Rehab S Alanazi, Yasmeen N Ruma, Carwyn S Hughes, Joel D A Tyndall

J Med Chem· June 2025

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Covalent Isothiocyanate Inhibitors of Macrophage Migration Inhibitory Factor as Potential Colorectal Cancer Treatments.
Lohitha Putha, Liang K Kok, Matthias Fellner, Malcolm T Rutledge, Allan B Gamble, Joel D A Tyndall

ChemMedChem· November 2024

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The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in .
Parham Hosseini, Mikhail V Keniya, Alia A Sagatova, Stephanie Toepfer, Christoph Müller, Joel D A Tyndall

J Fungi (Basel)· November 2024

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Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor.
China M Payne, Jo-Anne Baltos, Monica Langiu, Cam Sinh Lu, Joel D A Tyndall

Chembiochem· October 2024

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Synthesis and antifungal evaluation of novel triazole derivatives bearing a pyrazole-methoxyl moiety.
Yumeng Hao, Ruina Wang, Tingjunhong Ni, Brian C Monk, Joel D A Tyndall

Eur J Med Chem· September 2024

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A dual-targeting succinate dehydrogenase and FF-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Cara Adolph, Chen-Yi Cheung, Matthew B McNeil, William J Jowsey, Zoe C Williams, Joel D A Tyndall

Cell Chem Biol· April 2024

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Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Cytochrome Oxidase.
Aggie Lawer, Chelsea Tyler, Kiel Hards, Laura M Keighley, Chen-Yi Cheung, Joel D A Tyndall

ACS Med Chem Lett· October 2022

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S-217622, a 3CL Protease Inhibitor and Clinical Candidate for SARS-CoV-2.
Joel D A Tyndall

J Med Chem· May 2022

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Covalent cannabinoid receptor ligands - structural insight and selectivity challenges.
Ian Liddle, Michelle Glass, Joel D A Tyndall, Andrea J Vernall

RSC Med Chem· May 2022

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Structure-activity relationships of N-terminal variants of peptidomimetic tissue transglutaminase inhibitors.
Nicole M R McNeil, Eric W J Gates, Neda Firoozi, Nicholas J Cundy, Jessica Leccese, Joel D A Tyndall

Eur J Med Chem· March 2022

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Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia.
Jimin Hwang, Natalie Strange, Rami Mazraani, Matthew J Phillips, Allan B Gamble, Joel D A Tyndall

Eur J Med Chem· February 2022

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An amiloride derivative is active against the FF-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.
Kiel Hards, Chen-Yi Cheung, Natalie Waller, Cara Adolph, Laura Keighley, Joel D A Tyndall

Commun Biol· February 2022

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Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against : A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles.
Jimin Hwang, Sonya Mros, Allan B Gamble, Joel D A Tyndall, Arlene McDowell

Pharmaceutics· February 2022

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Characterisation of CYP51 as a Drug Target Using as Host.
Yasmeen N Ruma, Mikhail V Keniya, Joel D A Tyndall, Brian C Monk

J Fungi (Basel)· January 2022

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Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues.
Jimin Hwang, Natalie Strange, Matthew J A Phillips, Alexandra L Krause, Astra Heywood, Joel D A Tyndall

Eur J Med Chem· November 2021

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Chemical Synthesis of the PAX Protein Inhibitor EG1 and Its Ability to Slow the Growth of Human Colorectal Carcinoma Cells.
Lorissa McDougall, Jui Thiang Brian Kueh, Jake Ward, Joel D A Tyndall, Adele G Woolley

Front Oncol· October 2021

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Structural Insights into the Azole Resistance of the Darlington Strain Using Lanosterol 14α-Demethylase as a Surrogate.
Danyon O Graham, Rajni K Wilson, Yasmeen N Ruma, Mikhail V Keniya, Joel D A Tyndall

J Fungi (Basel)· October 2021

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A single point mutation converts a glutaryl-7-aminocephalosporanic acid acylase into an N-acyl-homoserine lactone acylase.
Shereen A Murugayah, Gary B Evans, Joel D A Tyndall, Monica L Gerth

Biotechnol Lett· July 2021

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Development of Covalent, Clickable Probes for Adenosine A and A Receptors.
Phuc N H Trinh, Daniel J W Chong, Katie Leach, Stephen J Hill, Joel D A Tyndall

J Med Chem· June 2021

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A multi-strategy platform for quality control and Q-markers screen of Chaiqin chengqi decoction.
Ge Liang, Jingyu Yang, Tingting Liu, Shisheng Wang, Yongjian Wen, Joel D A Tyndall

Phytomedicine· May 2021

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Targeting Macrophage Migration Inhibitory Factor in Acute Pancreatitis and Pancreatic Cancer.
Yongjian Wen, Wenhao Cai, Jingyu Yang, Xianghui Fu, Lohitha Putha, Joel D A Tyndall

Front Pharmacol· March 2021

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Cytostatic Action of Novel Histone Deacetylase Inhibitors in Androgen Receptor-Null Prostate Cancer Cells.
Zohaib Rana, Joel D A Tyndall, Muhammad Hanif, Christian G Hartinger, Rhonda J Rosengren

Pharmaceuticals (Basel)· January 2021

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