Publications by authors named "Allison Limpert"

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ULK1/2 Inhibitors that Degrade ATG13 Effectively Target KRAS-Mutant Cancers.
Patrick M Hagan, Huiyu Ren, Sonja N Brun, Fabiana I A Layng, Dhanya R Panickar, Allison S Limpert

bioRxiv· October 2025

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Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer.
Fabiana Izidro A L Layng, Huiyu Ren, Nicole A Bakas, Dhanya R Panickar, Lester J Lambert, Allison S Limpert

bioRxiv· September 2025

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Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein.
Carolina L Haass-Koffler, T Chase Francis, Pauravi Gandhi, Reesha Patel, Mohammad Naemuddin, Allison S Limpert

SLAS Discov· December 2022

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Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo.
Peibin Yue, Yinsong Zhu, Christine Brotherton-Pleiss, Wenzhen Fu, Nagendra Verma, Allison S Limpert

Cancer Lett· May 2022

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Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia.
Nicole Bata, Apirat Chaikuad, Nicole A Bakas, Allison S Limpert, Lester J Lambert

J Med Chem· January 2022

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Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer.
Huiyu Ren, Nicole A Bakas, Mitchell Vamos, Apirat Chaikuad, Allison S Limpert

J Med Chem· December 2020

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Autophagy in Cancer: Regulation by Small Molecules.
Allison S Limpert, Lester J Lambert, Nicole A Bakas, Nicole Bata, Sonja N Brun

Trends Pharmacol Sci· December 2018

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Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines.
Haixia Zou, Allison S Limpert, Jiwen Zou, Anna Dembo, Pooi-San Lee

ACS Chem Neurosci· March 2015

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Translational enhancers of EAAT2: therapeutic implications for neurodegenerative disease.
Allison S Limpert, Nicholas D P Cosford

J Clin Invest· March 2014

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Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS).
Allison S Limpert, Margrith E Mattmann, Nicholas D P Cosford

Beilstein J Org Chem· June 2013

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NF-κB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation.
Allison S Limpert, Shujun Bai, Malathi Narayan, Jiang Wu, Sung Ok Yoon

J Neurosci· February 2013

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Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.
Chhavy Tep, Mi Lyang Kim, Laura I Opincariu, Allison S Limpert, Jonah R Chan

J Biol Chem· January 2012

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Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation.
Allison S Limpert, Bruce D Carter

J Biol Chem· May 2010

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Nerve growth factor stimulates the concentration of TrkA within lipid rafts and extracellular signal-regulated kinase activation through c-Cbl-associated protein.
Allison S Limpert, J Colleen Karlo, Gary E Landreth

Mol Cell Biol· August 2007

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Mechanisms of statin-mediated inhibition of small G-protein function.
Andrew Cordle, Jessica Koenigsknecht-Talboo, Brandy Wilkinson, Allison Limpert, Gary Landreth

J Biol Chem· October 2005

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