Publications by authors named "Allison Rohner"

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Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer.
Rebecca A Gallego, Sujin Cho-Schultz, Matthew Del Bel, Anne-Marie Dechert-Schmitt, Joyann S Donaldson, Allison K Rohner

J Med Chem· December 2024

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Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.
Rebecca A Gallego, Louise Bernier, Hui Chen, Sujin Cho-Schultz, Loanne Chung, Allison Rohner

J Med Chem· April 2023

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A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice.
Timothy S Fisher, Andrea T Hooper, Justin Lucas, Tracey H Clark, Allison K Rohner

Cancer Immunol Immunother· February 2018

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Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.
Timothy S Fisher, Cris Kamperschroer, Theodore Oliphant, Victoria A Love, Paul D Lira, Allison Rohner

Cancer Immunol Immunother· October 2012

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Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier.
Allison Rohner, Mary E Spilker, Justine L Lam, Bernadette Pascual, Darian Bartkowski

Mol Cancer Ther· January 2012

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