Publications by authors named "Altaf Dar"

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Combinatorial therapy regimens targeting preclinical models of melanoma resistant to immune checkpoint blockade.
Imran Khan, Aida Rodriguez-Brotons, Anukana Bhattacharjee, Vladimir Bezrookove, Altaf Dar

J Clin Invest· September 2025

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miR-876-3p is a tumor suppressor on 9p21 that is inactivated in melanoma and targets ERK.
Vladimir Bezrookove, Imran Khan, Anukana Bhattacharjee, Juifang Fan, Robyn Jones, Altaf Dar

J Transl Med· August 2024

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The intersection of technology and mental health: enhancing access and care.
Mohd Altaf Dar, Mudasir Maqbool, Irfat Ara, Mehrukh Zehravi

Int J Adolesc Med Health· October 2023

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Pan-Cancer Pharmacogenomic Analysis of Patient-Derived Tumor Cells Using Clinically Relevant Drug Exposures.
Stephen H Chang, Ryan J Ice, Michelle Chen, Maxim Sidorov, Rinette W L Woo, Altaf A Dar

Mol Cancer Ther· September 2023

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BPTF promotes the progression of distinct subtypes of breast cancer and is a therapeutic target.
Vladimir Bezrookove, Imran A Khan, Mehdi Nosrati, James R Miller, Sean McAllister, Altaf A Dar

Front Oncol· November 2022

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Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience.
Michelle Chen, Damon Jian, Maxim Sidorov, Rinette W L Woo, Angela Kim, Altaf A Dar

J Pers Med· November 2022

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Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Altaf A Dar, Vladimir Bezrookove, Mehdi Nosrati, Ryan Ice, John M Patino

Proc Natl Acad Sci U S A· August 2022

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Prevalence of Homologous Recombination Pathway Gene Mutations in Melanoma: Rationale for a New Targeted Therapeutic Approach.
Kevin B Kim, Liliana Soroceanu, David de Semir, Sherri Z Millis, Jeffrey Ross, Altaf A Dar

J Invest Dermatol· August 2021

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Niraparib Suppresses Cholangiocarcinoma Tumor Growth by Inducing Oxidative and Replication Stress.
Vladimir Bezrookove, John M Patino, Mehdi Nosrati, Pierre-Yves Desprez, Sean McAllister, Altaf A Dar

Cancers (Basel)· August 2021

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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma.
Leticia Colyn, Marina Bárcena-Varela, Gloria Álvarez-Sola, M Ujue Latasa, Iker Uriarte, Altaf A Dar

Hepatology· June 2021

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Nuclear Receptor Coactivator NCOA3 Regulates UV Radiation-Induced DNA Damage and Melanoma Susceptibility.
David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A Dar, James R Miller

Cancer Res· June 2021

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Dinaciclib, a cyclin-dependent kinase inhibitor, suppresses cholangiocarcinoma growth by targeting CDK2/5/9.
Hera Saqub, Hannah Proetsch-Gugerbauer, Vladimir Bezrookove, Mehdi Nosrati, Edith M Vaquero, Altaf A Dar

Sci Rep· October 2020

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PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Kara R Scanlon, Eric Singer, Altaf A Dar

Proc Natl Acad Sci U S A· April 2020

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Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies.
Ryan J Ice, Michelle Chen, Max Sidorov, Tam Le Ho, Rinette W L Woo, Altaf A Dar

Br J Cancer· March 2020

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Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma.
Sarah Ursu, Shahana Majid, Caroline Garger, David de Semir, Vladimir Bezrookove, Altaf A Dar

Oncogenesis· August 2019

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Role of Elevated Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma.
Vladimir Bezrookove, Mehdi Nosrati, James R Miller, David De Semir, Altaf A Dar

Clin Cancer Res· September 2018

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PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A Dar, Clayton Wu

Proc Natl Acad Sci U S A· June 2018

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MicroRNA-720 Regulates E-cadherin-αE-catenin Complex and Promotes Renal Cell Carcinoma.
Nadeem S Bhat, Melissa Colden, Altaf A Dar, Sharanjot Saini, Prerna Arora

Mol Cancer Ther· December 2017

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MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2.
Melissa Colden, Altaf A Dar, Sharanjot Saini, Priya V Dahiya, Varahram Shahryari

Cell Death Dis· January 2017

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Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer.
Hannah Nip, Altaf A Dar, Sharanjot Saini, Melissa Colden, Shahryari Varahram

Oncotarget· October 2016

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Pre-clinical Orthotopic Murine Model of Human Prostate Cancer.
Varahram Shahryari, Hannah Nip, Sharanjot Saini, Altaf A Dar, Soichiro Yamamura

J Vis Exp· August 2016

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BPTF transduces MITF-driven prosurvival signals in melanoma cells.
Altaf A Dar, Shahana Majid, Vladimir Bezrookove, Binh Phan, Sarah Ursu

Proc Natl Acad Sci U S A· May 2016

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Tumor suppressor role of microRNA-1296 in triple-negative breast cancer.
Binh Phan, Shahana Majid, Sarah Ursu, David de Semir, Mehdi Nosrati, Altaf A Dar

Oncotarget· April 2016

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The role of BPTF in melanoma progression and in response to BRAF-targeted therapy.
Altaf A Dar, Mehdi Nosrati, Vladimir Bezrookove, David de Semir, Shahana Majid

J Natl Cancer Inst· February 2015

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Antitumor activity of miR-1280 in melanoma by regulation of Src.
Vera Sun, Wen B Zhou, Mehdi Nosrati, Shahana Majid, Suresh Thummala, Altaf A Dar

Mol Ther· January 2015

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