Publications by authors named "Alvina D Chu"

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Pharmacokinetics, Safety, Tolerability, and Exploratory Efficacy of Upadacitinib in Children with Severe Atopic Dermatitis.
Yuli Qian, Eliza M Raymundo, Shuai Hao, Kristina Unnebrink, Gweneth F Levy, Alvina D Chu

Clin Ther· October 2024

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Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis.
Mohamed Ismail, Eva Doelger, Doerthe Eckert, Alan D Irvine, Alvina D Chu

Br J Clin Pharmacol· October 2023

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Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies.
Emma Guttman-Yassky, Jacob P Thyssen, Jonathan I Silverberg, Kim A Papp, Amy S Paller, Alvina D Chu

J Allergy Clin Immunol· January 2023

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Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis: Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials.
Eric L Simpson, Kim A Papp, Andrew Blauvelt, Chia-Yu Chu, H Chih-Ho Hong, Alvina D Chu

JAMA Dermatol· April 2022

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Upadacitinib plus topical corticosteroids in atopic dermatitis: Week 52 AD Up study results.
Jonathan I Silverberg, Marjolein de Bruin-Weller, Thomas Bieber, Weily Soong, Kenji Kabashima, Alvina D Chu

J Allergy Clin Immunol· March 2022

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A phase 3 randomized, multicenter, double-blind study to evaluate the safety of upadacitinib in combination with topical corticosteroids in adolescent and adult patients with moderate-to-severe atopic dermatitis in Japan (Rising Up): An interim 24-week analysis.
Norito Katoh, Yukihiro Ohya, Hiroyuki Murota, Masanori Ikeda, Xiaofei Hu, Alvina D Chu

JAAD Int· March 2022

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Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One-Year Results of a Double-Blind, Placebo-Controlled Study and Open-Label Extension.
Atul Deodhar, Désirée van der Heijde, Joachim Sieper, Filip Van den Bosch, Walter P Maksymowych, Alvina D Chu

Arthritis Rheumatol· January 2022

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Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.
Andrew Blauvelt, Henrique D Teixeira, Eric L Simpson, Antonio Costanzo, Marjolein De Bruin-Weller, Alvina D Chu

JAMA Dermatol· September 2021

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Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials.
Emma Guttman-Yassky, Henrique D Teixeira, Eric L Simpson, Kim A Papp, Aileen L Pangan, Chia-Yu Chu, Alvina D Chu

Lancet· June 2021

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Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Kristian Reich, Henrique D Teixeira, Marjolein de Bruin-Weller, Thomas Bieber, Weily Soong, Alvina D Chu

Lancet· June 2021

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Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.
Désirée van der Heijde, In-Ho Song, Aileen L Pangan, Atul Deodhar, Filip van den Bosch, Alvina D Chu

Lancet· December 2019

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Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials.
Jeffrey Jones, Anthony Mato, Steven Coutre, John C Byrd, Richard R Furman, Alvina D Chu

Br J Haematol· August 2018

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Prognostic Factors for Complete Response to Ibrutinib in Patients With Chronic Lymphocytic Leukemia: A Pooled Analysis of 2 Clinical Trials.
Susan M O'Brien, Samantha Jaglowski, John C Byrd, Rajat Bannerji, Kristie A Blum, Alvina D Chu

JAMA Oncol· May 2018

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Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience.
Susan O'Brien, Richard R Furman, Steven Coutre, Ian W Flinn, Jan A Burger, Alvina D Chu

Blood· April 2018

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Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study.
Susan O'Brien, Jeffrey A Jones, Steven E Coutre, Anthony R Mato, Peter Hillmen, Alvina D Chu

Lancet Oncol· October 2016

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Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1.
Gloria Yiu, Tue K Rasmussen, Bahareh Ajami, David J Haddon, Alvina D Chu

Arthritis Rheumatol· May 2016

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Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease.
Nicole H Kattah, Evan W Newell, Justin Ansel Jarrell, Alvina D Chu, Jianming Xie

Proc Natl Acad Sci U S A· March 2015

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Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia.
John C Byrd, Jennifer R Brown, Susan O'Brien, Jacqueline C Barrientos, Neil E Kay, Stephen J Schuster, Anna Schuh, Alvina D Chu

N Engl J Med· July 2014

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Generic versus disease-specific measures of health-related quality of life in systemic lupus erythematosus.
Vibeke Strand, Alvina D Chu

J Rheumatol· September 2011

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Measuring outcomes in systemic lupus erythematosus clinical trials.
Vibeke Strand, Alvina D Chu

Expert Rev Pharmacoecon Outcomes Res· August 2011

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Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Huilian Qin, I-Fang Lee, Constadina Panagiotopoulos, Xiaoxia Wang, Alvina D Chu

Diabetes· March 2011

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Active and latent tuberculosis in patients with systemic lupus erythematosus living in the United States.
Alvina D Chu, Andrea H Polesky, Gulshan Bhatia, Thomas M Bush

J Clin Rheumatol· August 2009

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IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice.
Donna L Thibault, Alvina D Chu, Kareem L Graham, Imelda Balboni, Lowen Y Lee

J Clin Invest· April 2008

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