Publications by authors named "Amani Mahbub"

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Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation.
Akhmed Aslam, Faisal Minshawi, Hussain Almasmoum, Riyad Almaimani, Aiman Alsaegh, Amani A Mahbub

J Egypt Natl Canc Inst· March 2025

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Metformin and thymoquinone co-treatment enhance 5-fluorouracil cytotoxicity by suppressing the PI3K/mTOR/HIF1α pathway and increasing oxidative stress in colon cancer cells.
Wesam F Farrash, Akhmed Aslam, Riyad Almaimani, Faisal Minshawi, Hussain Almasmoum, Amani A Mahbub

Biofactors· December 2023

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Deferasirox and vitamin D co-therapy mitigates iron-induced renal injury by enhanced modulation of cellular anti-inflammatory, anti-oxidative stress, and iron regulatory pathways in rat.
Mazen M Ghaith, Mohamed El-Boshy, Hussain Almasmoum, Abdelghany H Abdelghany, Firas S Azzeh, Amani A Mahbub

J Trace Elem Med Biol· December 2022

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Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males.
Amani A Mahbub, Akhmed Aslam, Mohamed E Elzubier, Mohamed El-Boshy, Abdelghany H Abdelghany

Front Endocrinol (Lausanne)· October 2022

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17β-estradiol Enhances 5-Fluorouracil Anti-Cancer Activities in Colon Cancer Cell Lines.
Amani A Mahbub

Med Sci (Basel)· October 2022

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The effect of apigenin and chemotherapy combination treatments on apoptosis-related genes and proteins in acute leukaemia cell lines.
Amani A Mahbub, Christine L Le Maitre, Neil A Cross, Nicola Jordan-Mahy

Sci Rep· May 2022

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Therapeutic Strategies and Potential Actions of Female Sex Steroid Hormones and Their Receptors in Colon Cancer Based on Preclinical Studies.
Amani A Mahbub

Life (Basel)· April 2022

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Molecular Action of Polyphenols in Leukaemia and Their Therapeutic Potential.
Hamza A Alaswad, Amani A Mahbub, Christine L Le Maitre, Nicola Jordan-Mahy

Int J Mol Sci· March 2021

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Vitamin D and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti-inflammatory actions by remodeling cellular calcium pathways.
Mohamed El-Boshy, Bassem Refaat, Riyad A Almaimani, Abdelghany H Abdelghany, Jawwad Ahmad, Amani A Mahbub

J Biochem Mol Toxicol· March 2020

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Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat.
Mohamed El-Boshy, Mohammad A BaSalamah, Jawwad Ahmad, Shakir Idris, Amani Mahbub

Free Radic Biol Med· September 2019

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The remedial effect of Thymus vulgaris extract against lead toxicity-induced oxidative stress, hepatorenal damage, immunosuppression, and hematological disorders in rats.
Mohamed E El-Boshy, Bassem Refaat, Ahmed H Qasem, Anmar Khan, Mazen Ghaith, Amani Mahbub

Environ Sci Pollut Res Int· August 2019

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Polyphenols enhance the activity of alkylating agents in leukaemia cell lines.
Amani A Mahbub, Christine L Le Maitre, Sarah Haywood-Small, Neil A Cross, Nicola Jordan-Mahy

Oncotarget· July 2019

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Enhanced remedial effects for vitamin D and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic molecules.
Riyad A Almaimani, Hussain Almasmoum, Mazen M Ghaith, Mohamed El-Boshy, Shakir Idris, Amani Mahbub

Biochim Biophys Acta Mol Basis Dis· February 2019

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Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines.
Amani Mahbub, Christine Le Maitre, Sarah Haywood-Small, Neil Cross, Nicola Jordan-Mahy

Oncotarget· December 2017

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Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines.
Amani A Mahbub, Christine L Le Maitre, Sarah L Haywood-Small, Gordon J McDougall, Neil A Cross

Anticancer Agents Med Chem· December 2013

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