Publications by authors named "Amedeo Failli"

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Normal-phase automated mass-directed HPLC purification of a pyrrolobenzodiazepine library with vasopressin agonist activity.
Michael Kagan, Michael Chlenov, Sergey Melnikov, Oliver McConnell, Alvin C Bach, Amedeo Failli

J Comb Chem· October 2010

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Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists.
Aimee L Crombie, Thomas M Antrilli, Brandon A Campbell, David L Crandall, Amedeo A Failli

Bioorg Med Chem Lett· June 2010

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Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists.
Dahui Zhou, Gary P Stack, Jennifer Lo, Amedeo A Failli, Deborah A Evrard

J Med Chem· August 2009

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Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2.
Nicole T Hatzenbuhler, Reinhardt Baudy, Deborah A Evrard, Amedeo Failli, Boyd L Harrison

J Med Chem· November 2008

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Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase.
Adam M Gilbert, Amedeo Failli, Jay Shumsky, Youjun Yang, Anatoly Severin

J Med Chem· October 2006

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Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.
Amedeo A Failli, Jay S Shumsky, Robert J Steffan, Thomas J Caggiano, David K Williams

Bioorg Med Chem Lett· February 2006

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3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria.
Youjun Yang, Anatoly Severin, Rajiv Chopra, Girija Krishnamurthy, Guy Singh, Amedeo A Failli

Antimicrob Agents Chemother· February 2006

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Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
Diane Joseph-McCarthy, Kevin Parris, Adrian Huang, Amedeo Failli, Dominick Quagliato

J Med Chem· December 2005

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(4-Substituted-phenyl)-(5H-10,11-dihydro-pyrrolo [2,1-c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators.
Aranapakam M Venkatesan, George T Grosu, Amedeo A Failli, Peter S Chan, Joseph Coupet

Bioorg Med Chem Lett· November 2005

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4-Alkyl and 4,4'-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis.
Kristina M K Kutterer, Jamie M Davis, Guy Singh, Youjun Yang, William Hu, Amedeo Failli

Bioorg Med Chem Lett· May 2005

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