Publications by authors named "Amrita D Joshi"

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IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3.
Jadie Y Moon, Sonya J Wolf, Amrita D Joshi, He Zhang, James Shadiow

Nat Commun· December 2025

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TNF-α represses fibroblast to myofibroblast transition through the histone methyltransferase Setdb2.
Tyler M Bauer, Kevin D Mangum, Samuel D Buckley, James Shadiow, Amrita D Joshi

JCI Insight· November 2025

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Epigenetic alteration of smooth muscle cells regulates endothelin-dependent blood pressure and hypertensive arterial remodeling.
Kevin D Mangum, Qinmengge Li, Katherine Hartmann, Tyler M Bauer, Sonya J Wolf, Amrita D Joshi

J Clin Invest· June 2025

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The STAT3/SETDB2 axis dictates NF-κB-mediated inflammation in macrophages during wound repair.
Kevin D Mangum, Aaron denDekker, Qinmengge Li, Lam C Tsoi, Amrita D Joshi

JCI Insight· October 2024

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Diabetic Wound Keratinocytes Induce Macrophage JMJD3-Mediated Nlrp3 Expression via IL-1R Signaling.
Sonya J Wolf, Christopher O Audu, Jadie Y Moon, Amrita D Joshi, William J Melvin

Diabetes· September 2024

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The histone methyltransferase Mixed-lineage-leukemia-1 drives T cell phenotype via Notch signaling in diabetic tissue repair.
William J Melvin, Tyler M Bauer, Kevin D Mangum, Christopher O Audu, James Shadiow, Amrita D Joshi

JCI Insight· August 2024

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Epigenetic Alteration of Smooth Muscle Cells Regulates Endothelin-Dependent Blood Pressure and Hypertensive Arterial Remodeling.
Kevin D Mangum, Qinmengge Li, Tyler M Bauer, Sonya J Wolf, James Shadiow, Amrita D Joshi

medRxiv· July 2024

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Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells.
Christopher O Audu, Sonya J Wolf, Amrita D Joshi, Jadie Y Moon, William J Melvin

JCI Insight· June 2024

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The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase-Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development.
Frank M Davis, William J Melvin, Kevin Mangum, Lam C Tsoi, Amrita D Joshi

Ann Surg· September 2023

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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair.
Christopher O Audu, William J Melvin, Amrita D Joshi, Sonya J Wolf, Jadie Y Moon

Cell Mol Immunol· November 2022

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Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms.
Frank M Davis, Lam C Tsoi, William J Melvin, Aaron denDekker, Rachael Wasikowski, Amrita D Joshi

J Exp Med· June 2021

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Palmitate-TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing.
Frank M Davis, Aaron denDekker, Amrita D Joshi, Sonya J Wolf, Christopher Audu

Eur J Immunol· December 2020

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Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair.
Frank M Davis, Aaron denDekker, Andrew Kimball, Amrita D Joshi, Mahmoud El Azzouny

J Immunol· May 2020

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TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF.
Aaron D denDekker, Frank M Davis, Amrita D Joshi, Sonya J Wolf, Ronald Allen

JCI Insight· March 2020

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Sepsis Induces Prolonged Epigenetic Modifications in Bone Marrow and Peripheral Macrophages Impairing Inflammation and Wound Healing.
Frank M Davis, Matthew A Schaller, Aaron Dendekker, Amrita D Joshi, Andrew S Kimball

Arterioscler Thromb Vasc Biol· November 2019

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The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair.
Andrew S Kimball, Frank M Davis, Aaron denDekker, Amrita D Joshi, Matthew A Schaller

Immunity· August 2019

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Histone Methylation Directs Myeloid TLR4 Expression and Regulates Wound Healing following Cutaneous Tissue Injury.
Frank M Davis, Andrew Kimball, Aaron denDekker, Amrita D Joshi, Anna E Boniakowski

J Immunol· March 2019

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Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.
Andrew S Kimball, Amrita D Joshi, Anna E Boniakowski, Matthew Schaller, Jooho Chung

Front Immunol· June 2017

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Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection.
Brenda G Byrne, Jean-Francois Dubuisson, Amrita D Joshi, Jenny J Persson, Michele S Swanson

mBio· February 2013

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A micro RNA processing defect in rapidly progressing idiopathic pulmonary fibrosis.
Sameer R Oak, Lynne Murray, Athula Herath, Matthew Sleeman, Ian Anderson, Amrita D Joshi

PLoS One· November 2011

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Secrets of a successful pathogen: legionella resistance to progression along the autophagic pathway.
Amrita D Joshi, Michele S Swanson

Front Microbiol· July 2011

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TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis.
Glenda Trujillo, Alessia Meneghin, Kevin R Flaherty, Lynette M Sholl, Jeffrey L Myers, Amrita D Joshi

Sci Transl Med· November 2010

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Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages.
Amrita D Joshi, Sameer R Oak, Adam J Hartigan, William G Finn, Steven L Kunkel

BMC Immunol· October 2010

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Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis.
Daniel J Fong, Cory M Hogaboam, Yosuke Matsuno, Shizuo Akira, Satoshi Uematsu, Amrita D Joshi

Immunology· May 2010

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Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation.
Toshihiro Ito, Matthew Schaller, Tracy Raymond, Amrita D Joshi, Ana L Coelho

Am J Respir Crit Care Med· December 2009

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