Publications by authors named "Amy Rappaport"

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Self-amplifying mRNA expressing COBRA hemagglutinin elicits long-lasting, broadly reactive antibodies against seasonal influenza A viruses.
Spencer R Pierce, Hua Shi, Camila Caetano, David A Prots, Michael A Carlock, Amy R Rappaport

Vaccine· August 2025

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Differential shaping of T cell responses elicited by heterologous ChAd68/self-amplifying mRNA SIV vaccine in macaques in combination with αCTLA4, αPD-1, or FLT3R agonist.
Amy R Rappaport, Elena Bekerman, Gregory R Boucher, Janette Sung, Brian Carr

J Immunol· March 2025

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A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.
Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson

Nat Med· April 2024

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GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults.
Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport

Nat Commun· June 2023

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Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results.
Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan

Nat Med· August 2022

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Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection.
Amy R Rappaport, Sue-Jean Hong, Ciaran D Scallan, Leonid Gitlin, Arvin Akoopie

Nat Commun· June 2022

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How do I work with fertility loss as a pregnant therapist? A case study and discussion about pregnancy self-disclosure in the oncology setting.
Melanie McDonald, Amy Rappaport, Alan Bates

J Psychosoc Oncol· April 2022

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NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes.
Anju Singh, Anneleen Daemen, Dorothee Nickles, Sang-Min Jeon, Oded Foreman, Amy Rappaport

Clin Cancer Res· February 2021

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Engineering of a miniaturized, robotic clinical laboratory.
Marilyn B Nourse, Kate Engel, Samartha G Anekal, Jocelyn A Bailey, Pradeep Bhatta, Amy R Rappaport

Bioeng Transl Med· January 2018

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Direct and indirect targeting of MYC to treat acute myeloid leukemia.
Sam Brondfield, Sushma Umesh, Alexandra Corella, Johannes Zuber, Amy R Rappaport

Cancer Chemother Pharmacol· July 2015

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Genetically engineered knock-in and conditional knock-in mouse models of cancer.
Amy Rappaport, Leisa Johnson

Cold Spring Harb Protoc· September 2014

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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.
Chong Chen, Yu Liu, Amy R Rappaport, Thomas Kitzing, Nikolaus Schultz

Cancer Cell· May 2014

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Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.
Michael Bots, Inge Verbrugge, Benjamin P Martin, Jessica M Salmon, Margherita Ghisi, Amy R Rappaport

Blood· February 2014

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An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.
Rachel J Bergerson, Lara S Collier, Aaron L Sarver, Raha A Been, Sanne Lugthart, Amy R Rappaport

Blood· May 2012

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A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.
Wen Xue, Thomas Kitzing, Stephanie Roessler, Johannes Zuber, Alexander Krasnitz, Amy R Rappaport

Proc Natl Acad Sci U S A· May 2012

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Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.
Stefan P Glaser, Erinna F Lee, Evelyn Trounson, Philippe Bouillet, Andrew Wei, Amy R Rappaport

Genes Dev· January 2012

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Johannes Zuber, Junwei Shi, Eric Wang, Amy R Rappaport, Harald Herrmann

Nature· August 2011

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An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.
Johannes Zuber, Amy R Rappaport, Weijun Luo, Eric Wang, Chong Chen

Genes Dev· August 2011

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Mouse models of human AML accurately predict chemotherapy response.
Johannes Zuber, Ina Radtke, Timothy S Pardee, Zhen Zhao, Amy R Rappaport

Genes Dev· April 2009

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