Publications by authors named "Andre Horatscheck"

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Inhibition of the Clathrin Terminal Domain-Amphiphysin Protein-Protein Interaction. Probing the Pitstop 2 Aromatic Moiety.
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Andre Horatscheck

ChemMedChem· August 2025

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Next-generation small molecule inhibitors of clathrin function acutely inhibit endocytosis.
André Horatscheck, Michael Krauß, Haydar Bulut, Valerie Chambon, Massilullah Shafaq Zadah

Structure· May 2025

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Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite .
Jean Dam, Grant A Boyle, André Horatscheck, John G Woodland, Claire Le Manach

J Med Chem· May 2025

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Another decade of antimalarial drug discovery: New targets, tools and molecules.
John G Woodland, André Horatscheck, Candice Soares de Melo, Godwin A Dziwornu, Dale Taylor

Prog Med Chem· October 2024

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Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition.
Murat Kücükdisli, Hassen Bel-Abed, Davide Cirillo, Wen-Ting Lo, Nina-Louisa Efrém, André Horatscheck

J Med Chem· October 2023

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Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Wen-Ting Lo, Hassane Belabed, Murat Kücükdisli, Juliane Metag, Yvette Roske, André Horatscheck

Nat Chem Biol· January 2023

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Correction to "Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and Efficacy in the NSG Mouse Model".
André Horatscheck, Ana Andrijevic, Aloysius T Nchinda, Claire Le Manach, Tanya Paquet

J Med Chem· February 2021

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Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite and Optimization Efforts.
Claire Le Manach, Jean Dam, John G Woodland, Gurminder Kaur, Lutete P Khonde, André Horatscheck

J Med Chem· February 2021

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Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Janette Reader, Mariëtte E van der Watt, Dale Taylor, Claire Le Manach, Nimisha Mittal, Andre Horatscheck

Nat Commun· January 2021

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Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and Efficacy in the NSG Mouse Model.
André Horatscheck, Ana Andrijevic, Aloysius T Nchinda, Claire Le Manach, Tanya Paquet

J Med Chem· November 2020

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Plasmodial Kinase Inhibitors: License to Cure?
Diego González Cabrera, André Horatscheck, Colin R Wilson, Greg Basarab, Charles J Eyermann

J Med Chem· September 2018

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Direct Experimental Evidence for Halogen-Aryl π Interactions in Solution from Molecular Torsion Balances.
Han Sun, André Horatscheck, Vera Martos, Max Bartetzko, Ulrike Uhrig

Angew Chem Int Ed Engl· June 2017

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5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.
Mark J Robertson, André Horatscheck, Samantha Sauer, Lisa von Kleist, Jennifer R Baker

Org Biomol Chem· November 2016

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Alzheimer's disease: identification and development of β-secretase (BACE-1) binding fragments and inhibitors by dynamic ligation screening (DLS).
María Isabel Fernández-Bachiller, André Horatscheck, Michael Lisurek, Jörg Rademann

ChemMedChem· July 2013

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Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.
André Horatscheck, Stefan Wagner, Jutta Ortwein, Boo Geun Kim, Michael Lisurek

Angew Chem Int Ed Engl· September 2012

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