Publications by authors named "Janette Reader"

Claim this Profile
C
Characterizing the quick-killing mechanism of action of azithromycin analogs against malaria parasites.
Emma Y Mao, William Nguyen, Gouranga P Jana, Bikash C Maity, Samuel Pazicky, Janette Reader

Antimicrob Agents Chemother· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Ferrocenyl Quinoline-Benzimidazole Hybrids: A Multistage Strategy to Combat Drug-Resistant Malaria.
Taryn M Golding, Larnelle F Garnie, Tayla Rabie, Janette Reader, Lyn-Marié Birkholtz

Inorg Chem· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Inhibitors of Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and Efficacy in a Humanized Mouse Malaria Infection Model.
Godwin A Dziwornu, Mmakwena M Mmonwa, Dina Coertzen, Liezl Krugmann, Nicolaas Salomane, Janette Reader

J Med Chem· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.
John G Woodland, Dina Coertzen, Kathryn J Wicht, Virginia Franco Hidalgo, Charisse Flerida A Pasaje, Janette Reader

Angew Chem Int Ed Engl· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against via Dual Inhibition of Ark1 and Hemozoin Formation.
Kathryn J Wicht, John G Woodland, Larnelle F Garnie, Henrico Langeveld, Dale Taylor, Janette Reader

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.
Samuel Gachuhi, Stephanie Kamunya, Stephen Fienberg, Lynn Wambua, Nicolaas Salomane, Janette Reader

J Med Chem· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.
Paula-Josefina Gomez-Gonzalez, Antima Gupta, Laura G Drought, Avnish Patel, John Okombo, Janette Reader

Sci Adv· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Eliminating malaria transmission requires targeting immature and mature gametocytes through lipoidal uptake of antimalarials.
Mariska Naude, Ashleigh van Heerden, Janette Reader, Mariëtte van der Watt, Jandeli Niemand

Nat Commun· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against .
Savannah J Watson, Mariëtte E van der Watt, Anjo Theron, Janette Reader, Sizwe Tshabalala

ACS Infect Dis· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
2
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Phosphatidylinositol-4-kinase and Hemozoin Formation with Efficacy.
Godwin Akpeko Dziwornu, Donald Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Janette Reader

J Med Chem· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring the modulatory influence on the antimalarial activity of amodiaquine using scaffold hybridisation with ferrocene integration.
Mziyanda Mbaba, Taryn M Golding, Reinner O Omondi, Roxanne Mohunlal, Timothy J Egan, Janette Reader

Eur J Med Chem· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and Efficacy in a Mouse Malaria Infection Model.
Dickson Mambwe, Constance M Korkor, Amanda Mabhula, Zama Ngqumba, Cleavon Cloete, Janette Reader

J Med Chem· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New Transmission-Selective Antimalarial Agents through Hit-to-Lead Optimization of 2-([1,1'-Biphenyl]-4-carboxamido)benzoic Acid Derivatives.
Janette Reader, Daniel F L Opperman, Mariëtte E van der Watt, Anjo Theron, Meta Leshabane

Chembiochem· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro dual activity of Aloe marlothii roots and its chemical constituents against Plasmodium falciparum asexual and sexual stage parasites.
Sephora Mutombo Mianda, Luke Invernizzi, Mariëtte E van der Watt, Janette Reader, Phanankosi Moyo

J Ethnopharmacol· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple kinases and life cycle stages.
Lauren B Arendse, James M Murithi, Tarrick Qahash, Charisse Flerida A Pasaje, Luiz C Godoy, Janette Reader

Sci Transl Med· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Streamlined and Robust Stage-Specific Profiling of Gametocytocidal Compounds Against .
Janette Reader, Mariette E van der Watt, Lyn-Marié Birkholtz

Front Cell Infect Microbiol· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination.
Mariëtte E van der Watt, Janette Reader, Lyn-Marié Birkholtz

Front Cell Infect Microbiol· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adsorption to the Surface of Hemozoin Crystals: Structure-Based Design and Synthesis of Amino-Phenoxazine β-Hematin Inhibitors.
Tania Olivier, Leigh Loots, Michélle Kok, Marianne de Villiers, Janette Reader

ChemMedChem· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.
Yabalu Z Abacha, Arnold Donkor Forkuo, Stephen Y Gbedema, Nimisha Mittal, Sabine Ottilie, Janette Reader

Front Pharmacol· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development.
Hilde von Grüning, Mariel Coradin, Mariel R Mendoza, Janette Reader, Simone Sidoli

Mol Cell Proteomics· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The ecdysone receptor regulates several key physiological factors in Anopheles funestus.
Surina Maharaj, Elodie Ekoka, Erica Erlank, Luisa Nardini, Janette Reader

Malar J· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage Parasites, DMPK Properties, and the Case for Artemiside.
Liezl Gibhard, Dina Coertzen, Janette Reader, Mariëtte E van der Watt, Lyn-Marie Birkholtz

Pharmaceutics· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites.
Jandeli Niemand, Riëtte van Biljon, Mariëtte van der Watt, Ashleigh van Heerden, Janette Reader

ACS Infect Dis· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against In Vitro.
Dickson Mambwe, Malkeet Kumar, Richard Ferger, Dale Taylor, Mathew Njoroge, Janette Reader

ACS Med Chem Lett· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antimalarial Benzimidazole Derivatives Incorporating Phenolic Mannich Base Side Chains Inhibit Microtubule and Hemozoin Formation: Structure-Activity Relationship and Oral Efficacy Studies.
Godwin Akpeko Dziwornu, Dina Coertzen, Meta Leshabane, Constance M Korkor, Cleavon K Cloete, Janette Reader

J Med Chem· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis