Publications by authors named "Andrea Conlan"

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A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Sagi Tamir, Yael Eisenberg-Domovich, Andrea R Conlan, Jason T Stofleth, Colin H Lipper

Acta Crystallogr D Biol Crystallogr· June 2014

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Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs.
Sagi Tamir, John A Zuris, Lily Agranat, Colin H Lipper, Andrea R Conlan

PLoS One· April 2014

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Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1.
Sagi Tamir, Shahar Rotem-Bamberger, Chen Katz, Faruck Morcos, Kendra L Hailey, Andrea R Conlan

Proc Natl Acad Sci U S A· April 2014

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NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth.
Yang-Sung Sohn, Sagi Tamir, Luhua Song, Dorit Michaeli, Imad Matouk, Andrea R Conlan

Proc Natl Acad Sci U S A· September 2013

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Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism.
Rachel Nechushtai, Andrea R Conlan, Yael Harir, Luhua Song, Ohad Yogev

Plant Cell· May 2012

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Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein.
John A Zuris, Yael Harir, Andrea R Conlan, Maya Shvartsman, Dorit Michaeli

Proc Natl Acad Sci U S A· August 2011

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Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
Andrea R Conlan, Mark L Paddock, Christina Homer, Herbert L Axelrod, Aina E Cohen

Acta Crystallogr D Biol Crystallogr· June 2011

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Engineering the redox potential over a wide range within a new class of FeS proteins.
John A Zuris, Danny A Halim, Andrea R Conlan, Edward C Abresch, Rachel Nechushtai

J Am Chem Soc· September 2010

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Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET.
Michelle M Dicus, Andrea Conlan, Rachel Nechushtai, Patricia A Jennings, Mark L Paddock

J Am Chem Soc· February 2010

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Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2.
Andrea R Conlan, Herbert L Axelrod, Aina E Cohen, Edward C Abresch, John Zuris

J Mol Biol· September 2009

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The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain.
Andrea R Conlan, Mark L Paddock, Herbert L Axelrod, Aina E Cohen, Edward C Abresch

Acta Crystallogr Sect F Struct Biol Cryst Commun· July 2009

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Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center.
Timothy F Tirrell, Mark L Paddock, Andrea R Conlan, Eric J Smoll, Rachel Nechushtai

Biochemistry· June 2009

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