Publications by authors named "Andrea Lindgren"

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The Pharmacokinetic and Pharmacodynamic Relationship of Clinically Used Antiseizure Medications in the Maximal Electroshock Seizure Model in Rodents.
Luis Bettio, Girish Bankar, Celine M Dubé, Karen Nelkenbrecher, Maja Filipovic, Andrea Lindgren

Int J Mol Sci· July 2025

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The contribution of Na1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na1.6 gain-of-function (GOF) mouse seizure control.
James P Johnson, Thilo Focken, Parisa Karimi Tari, Celine Dube, Samuel J Goodchild, Andrea Lindgren

Br J Pharmacol· October 2024

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NBI-921352, a first-in-class, Na1.6 selective, sodium channel inhibitor that prevents seizures in gain-of-function mice, and wild-type mice and rats.
J P Johnson, Thilo Focken, Kuldip Khakh, Parisa Karimi Tari, Celine Dube, Andrea Lindgren

Elife· March 2022

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Identification of aryl sulfonamides as novel and potent inhibitors of Na1.5.
Shaoyi Sun, Qi Jia, Alla Y Zenova, Sophia Lin, Angela Hussainkhel, Andrea Lindgren

Bioorg Med Chem Lett· August 2021

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Discovery of Acyl-sulfonamide Na1.7 Inhibitors GDC-0276 and GDC-0310.
Brian S Safina, Steven J McKerrall, Shaoyi Sun, Chien-An Chen, Sultan Chowdhury, Andrea Lindgren

J Med Chem· March 2021

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Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Thilo Focken, Kristen Burford, Michael E Grimwood, Alla Zenova, Jean-Christophe Andrez, Andrea Lindgren

J Med Chem· November 2019

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Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na) 1.7 with Potent Analgesic Activity.
Shaoyi Sun, Qi Jia, Alla Y Zenova, Michael S Wilson, Sultan Chowdhury, Andrea Lindgren

J Med Chem· January 2019

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Selective Na1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain.
Girish Bankar, Samuel J Goodchild, Sarah Howard, Karen Nelkenbrecher, Matthew Waldbrook, Andrea Lindgren

Cell Rep· September 2018

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COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.
Miklos Gulyas, Johanna Sofia Margareta Mattsson, Andrea Lindgren, Lars Ek, Kristina Lamberg Lundström

Acta Oncol· February 2018

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Using Whole-Exome Sequencing to Identify Genetic Markers for Carboplatin and Gemcitabine-Induced Toxicities.
Henrik Gréen, Johanna Hasmats, Ilya Kupershmidt, Daniel Edsgärd, Luigi de Petris, Andrea Lindgren

Clin Cancer Res· January 2016

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Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice.
Shaoyi Sun, Richard Dean, Qi Jia, Alla Zenova, Jing Zhong, Andrea Lindgren

Bioorg Med Chem· December 2013

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Predictive role of plasma vascular endothelial growth factor for the effect of celecoxib in advanced non-small cell lung cancer treated with chemotherapy.
Sverre Sörenson, Helena Fohlin, Andrea Lindgren, Magnus Lindskog, Bengt Bergman

Eur J Cancer· January 2013

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