Publications by authors named "Andreas Janzer"

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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses.
Simon Heller, Sarah Glaeske, Katja Gluske, Juliane Paul, Annika Böhme, Andreas Janzer

Clin Exp Med· December 2023

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De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Diana D Shi, Milan R Savani, Michael M Levitt, Adam C Wang, Jennifer E Endress, Andreas Janzer

Cancer Cell· September 2022

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The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.
Sven Christian, Claudia Merz, Laura Evans, Stefan Gradl, Henrik Seidel, Andreas Janzer

Leukemia· October 2019

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Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation.
Zhe Ji, Lizhi He, Asaf Rotem, Andreas Janzer, Christine S Cheng

Nat Commun· May 2018

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Overexpression of histone demethylase Fbxl10 leads to enhanced migration in mouse embryonic fibroblasts.
Magdalena Rohde, Elisabeth Sievers, Andreas Janzer, Dominica Willmann, Angela Egert

Exp Cell Res· November 2016

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Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
David B Sykes, Youmna S Kfoury, François E Mercier, Mathias J Wawer, Jason M Law, Andreas Janzer

Cell· September 2016

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Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation.
Asaf Rotem, Andreas Janzer, Benjamin Izar, Zhe Ji, John G Doench

Proc Natl Acad Sci U S A· May 2015

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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells.
Andreas Janzer, Natalie J German, Karina N Gonzalez-Herrera, John M Asara, Marcia C Haigis

Proc Natl Acad Sci U S A· July 2014

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Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor.
Dominica Willmann, Soyoung Lim, Stefan Wetzel, Eric Metzger, Anett Jandausch, Andreas Janzer

Int J Cancer· December 2012

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The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts.
Andreas Janzer, Katrin Stamm, Astrid Becker, Andreas Zimmer, Reinhard Buettner

J Biol Chem· September 2012

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Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components.
Andreas Janzer, Soyoung Lim, Florian Fronhoffs, Naima Niazy, Reinhard Buettner

Biochem Biophys Res Commun· May 2012

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Proteolytic processing of the serine protease matriptase-2: identification of the cleavage sites required for its autocatalytic release from the cell surface.
Marit Stirnberg, Eva Maurer, Angelika Horstmeyer, Sonja Kolp, Stefan Frank, Andreas Janzer

Biochem J· August 2010

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Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology.
Soyoung Lim, Andreas Janzer, Astrid Becker, Andreas Zimmer, Roland Schüle

Carcinogenesis· March 2010

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