Publications by authors named "Andrei Gudkov"

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A phase 1 study of intra-arterial CBL0137 in extremity melanomas and sarcomas.
Joseph J Skitzki, Minhyung Kim, Daniel T Fisher, John M Kane, Han Yu, Andrei V Gudkov

Surg Oncol· August 2025

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The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response.
Ruby Pandher, Chengyuan Xue, Laura D Gamble, Giorgio Milazzo, Simone Di Giacomo, Andrei V Gudkov

Proc Natl Acad Sci U S A· June 2025

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FACT inhibitor CBL0137, administered in an optimized schedule, potentiates radiation therapy for glioblastoma by suppressing DNA damage repair.
Tara A Barone, Denisha L Robinson, Jingxin Qiu, Katerina V Gurova, Andrei A Purmal, Andrei V Gudkov

J Neurooncol· December 2024

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The reconstruction of evolutionary dynamics of processed pseudogenes indicates deep silencing of "retrobiome" in naked mole rat.
Valeria Kogan, Ivan Molodtsov, Daria I Fleyshman, Olga V Leontieva, Igor E Koman, Andrei V Gudkov

Proc Natl Acad Sci U S A· November 2024

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Enhancing Anti-PD-1 Immunotherapy by Targeting MDSCs via Hepatic Arterial Infusion in Breast Cancer Liver Metastases.
Minhyung Kim, Colin A Powers, Daniel T Fisher, Amy W Ku, Nickolay Neznanov, Andrei V Gudkov

Cancers (Basel)· November 2024

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FACT inhibitor CBL0137, administered in an optimized schedule, potentiates radiation therapy for glioblastoma by suppressing DNA damage repair.
Tara A Barone, Denisha L Robinson, Jingxin Qiu, Katerina V Gurova, Andrei A Purmal, Andrei V Gudkov

Res Sq· September 2024

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Anticancer Plant Secondary Metabolites Induce Linker Histone Depletion from Chromatin.
Olga Vlasova, Irina Antonova, Roman Zenkov, Denis Naberezhnov, Gennady Belitsky, Andrei Gudkov

Front Biosci (Landmark Ed)· August 2024

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Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis.
Yosuke Sakamachi, Emma Wiley, Alma Solis, Collin G Johnson, Xianglin Meng, Andrei V Gudkov

bioRxiv· April 2024

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Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans.
Alexandra V Vylegzhanina, Ivan A Bespalov, Ksenia A Novototskaya-Vlasova, Brandon M Hall, Anatoli S Gleiberman, Andrei V Gudkov

Cancer Res Commun· November 2023

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Targeting Features of Curaxin CBL0137 on Hematological Malignancies In Vitro and In Vivo.
Timur I Fetisov, Anna A Borunova, Alina S Antipova, Elena E Antoshina, Lubov S Trukhanova, Andrei Gudkov

Biomedicines· January 2023

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Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors.
Ksenia A Novototskaya-Vlasova, Nickolay S Neznanov, Ivan Molodtsov, Brandon M Hall, Mairead Commane, Andrei V Gudkov

Proc Natl Acad Sci U S A· December 2022

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Unsupervised learning of aging principles from longitudinal data.
Konstantin Avchaciov, Marina P Antoch, Ekaterina L Andrianova, Andrei E Tarkhov, Leonid I Menshikov, Andrei V Gudkov

Nat Commun· November 2022

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Assessment of Sex, Age, and Metabolism Relationships to Serum Thyroid Concentrations in Retired Alaskan Husky Sled Dogs.
Margret Lenfest, John P Loftus, Heather J Huson, Andrei Gudkov, Katerina Andrianova

Front Vet Sci· June 2022

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Targeted Modulation of Interferon Response-Related Genes with IFN-Alpha/Lambda Inhibition.
Debpali Sur, Katerina Leonova, Bar Levi, Shany Ivon Markowitz, Raichel Cohen-Harazi, Andrei Gudkov

Int J Mol Sci· June 2022

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The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Andrei V Gudkov

Front Oncol· May 2022

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Alkaloid-rich fraction of Ervatamia coronaria sensitizes colorectal cancer through modulating AMPK and mTOR signalling pathways.
Naibedya Dutta, Deepak Bharadwaj Pemmaraju, Suvranil Ghosh, Asif Ali, Ayan Mondal, Andrei V Gudkov

J Ethnopharmacol· January 2022

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Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Ian Miller, Max Totrov, Lioubov Korotchkina, Denis N Kazyulkin, Andrei V Gudkov

Nucleic Acids Res· November 2021

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Signaling through TLR5 mitigates lethal radiation damage by neutrophil-dependent release of MMP-9.
Craig M Brackett, Kellee F Greene, Alyssa R Aldrich, Nicholas H Trageser, Srabani Pal, Andrei V Gudkov

Cell Death Discov· September 2021

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Development of infrastructure for a systemic multidisciplinary approach to study aging in retired sled dogs.
Daria I Fleyshman, Joseph J Wakshlag, Heather J Huson, John P Loftus, Natasha J Olby, Andrei V Gudkov

Aging (Albany NY)· September 2021

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Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Lin Xiao, Klaartje Somers, Jayne Murray, Ruby Pandher, Mawar Karsa, Andrei V Gudkov

Clin Cancer Res· August 2021

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Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules.
Catherine A Burkhart, Michelle Haber, Murray D Norris, Andrei V Gudkov, Mikhail A Nikiforov

Methods Mol Biol· August 2021

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Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo.
Suvranil Ghosh, Naibedya Dutta, Pinaki Banerjee, Rahul L Gajbhiye, Hossainoor Rahaman Sareng, Andrei V Gudkov

Free Radic Biol Med· August 2021

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Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53.
Natalia Fedtsova, Elena A Komarova, Kellee F Greene, Liliya R Novototskaya, Ivan Molodtsov, Andrei V Gudkov

Cell Death Dis· May 2021

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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M Giorgi, Jie Liu, Andrei V Gudkov

Cell Rep· April 2021

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