Publications by authors named "Andrew B Benowitz"

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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Patrick J Brennan, Rebecca E Saunders, Mary Spanou, Sarah E Singleton, Marta Serafini, Andrew B Benowitz

ACS Chem Biol· November 2025

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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Patrick J Brennan, Rebecca E Saunders, Mary Spanou, Marta Serafini, Liang Sun, Andrew B Benowitz

bioRxiv· March 2024

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Challenges and opportunities for PROTAC delivery.
Andrew B Benowitz, Paul T Scott-Stevens, John D Harling

Future Med Chem· January 2022

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The PROTACtable genome.
Melanie Schneider, Chris J Radoux, Andrew Hercules, David Ochoa, Ian Dunham, Andrew B Benowitz

Nat Rev Drug Discov· October 2021

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Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.
Robert P Law, Joao Nunes, Chun-Wa Chung, Marcus Bantscheff, Karol Buda, Andrew B Benowitz

Angew Chem Int Ed Engl· October 2021

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Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.
Melissa B Pappalardi, Kathryn Keenan, Mark Cockerill, Wendy A Kellner, Alexandra Stowell, Andrew B Benowitz

Nat Cancer· October 2021

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A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications.
Peter Stacey, Hannah Lithgow, Xiao Lewell, Agnieszka Konopacka, Stephen Besley, Andrew B Benowitz

SLAS Discov· August 2021

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and induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
Aidan G Gilmartin, Arthur Groy, Elizabeth R Gore, Charity Atkins, Edward R Long, Andrew B Benowitz

Haematologica· July 2021

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The therapeutic potential of PROTACs.
Andrew B Benowitz, Katherine L Jones, John D Harling

Expert Opin Ther Pat· January 2021

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Structural Insights into PROTAC-Mediated Degradation of Bcl-xL.
Chun-Wa Chung, Han Dai, Esther Fernandez, Christopher P Tinworth, Ian Churcher, Andrew B Benowitz

ACS Chem Biol· September 2020

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Selective CDK6 degradation mediated by cereblon, VHL, and novel IAP-recruiting PROTACs.
Niall A Anderson, Jenni Cryan, Adil Ahmed, Han Dai, Grant A McGonagle, Andrew B Benowitz

Bioorg Med Chem Lett· May 2020

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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.
Alina Mares, Afjal H Miah, Ian E D Smith, Mark Rackham, Aditya R Thawani, Andrew B Benowitz

Commun Biol· March 2020

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A hit deconstruction approach for the discovery of fetal hemoglobin inducers.
Andrew B Benowitz, H Christian Eberl, Connie L Erickson-Miller, Aidan G Gilmartin, Elizabeth R Gore

Bioorg Med Chem Lett· December 2018

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Fragment-based discovery of 6-azaindazoles as inhibitors of bacterial DNA ligase.
Steven Howard, Nader Amin, Andrew B Benowitz, Elisabetta Chiarparin, Haifeng Cui

ACS Med Chem Lett· December 2013

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Total Synthesis of Mycolactones A and B.
Fengbin Song, Steve Fidanze, Andrew B Benowitz, Yoshito Kishi

Tetrahedron· June 2007

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Total synthesis of the mycolactones.
Fengbin Song, Steve Fidanze, Andrew B Benowitz, Yoshito Kishi

Org Lett· February 2002

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