Publications by authors named "Andrew Coop"

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Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders.
Chad R Johnson, Brian D Kangas, Emily M Jutkiewicz, Jack Bergman, Andrew Coop

Biomedicines· February 2022

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Novel Antimuscarinic Antidepressant-like Compounds with Reduced Effects on Cognition.
Chad R Johnson, Brian D Kangas, Emily M Jutkiewicz, Gail Winger, Jack Bergman, Andrew Coop

J Pharmacol Exp Ther· June 2021

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Recent advances in the targeting of human DNA ligase I as a potential new strategy for cancer treatment.
Mohammad Saquib, Mohd Imran Ansari, Chad R Johnson, Shahnaaz Khatoon, Mohd Kamil Hussain, Andrew Coop

Eur J Med Chem· November 2019

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The Effects of Morphine, Baclofen, and Buspirone Alone and in Combination on Schedule-Controlled Responding and Hot Plate Antinociception in Rats.
Jenny L Wilkerson, Jasmine S Felix, Luis F Restrepo, Mohd Imran Ansari, Andrew Coop

J Pharmacol Exp Ther· September 2019

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Tetrabutylammonium Bromide-Promoted Metal-Free, Efficient, Rapid, and Scalable Synthesis of N-Aryl Amines.
Chad R Johnson, Mohd Imran Ansari, Andrew Coop

ACS Omega· September 2018

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Synthesis and Structural Elucidation of a Pyranomorphinan Opioid and in Vitro Studies.
Mohd Imran Ansari, Jason R Healy, Kellie Hom, Jeffrey R Deschamps, Rae R Matsumoto, Andrew Coop

Org Lett· May 2018

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Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands.
Jason R Healy, Padmavani Bezawada, Nicholas W Griggs, Andrea L Devereaux, Rae R Matsumoto, Andrew Coop

Bioorg Med Chem Lett· February 2017

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Conformational Heterogeneity of Intracellular Loop 3 of the μ-opioid G-protein Coupled Receptor.
Jing Huang, Sirish Kaushik Lakkaraju, Andrew Coop, Alexander D MacKerell

J Phys Chem B· November 2016

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Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
Michael C Cavalier, Mohd Imran Ansari, Adam D Pierce, Paul T Wilder, Laura E McKnight, Andrew Coop

J Med Chem· January 2016

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Opioids and efflux transporters. Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues.
Matthew D Metcalf, Andrew D Rosicky, Hazem E Hassan, Natalie D Eddington, Andrew Coop

Bioorg Med Chem Lett· August 2014

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Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor.
Tanila Ben Haddou, Davide Malfacini, Girolamo Calo, Mario D Aceto, Louis S Harris, Andrew Coop

Mol Pain· July 2014

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A One-Step Synthesis of -Bromocodide from Codeine.
Christopher W Cunningham, Jeffrey R Deschamps, Andrew Coop

J Pharm Sci Pharmacol· March 2014

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σ Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation.
Matthew J Robson, Michael J Seminerio, Christopher R McCurdy, Andrew Coop, Rae R Matsumoto

Pharmacol Rep· February 2014

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Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands.
William C Motel, Jason R Healy, Eddy Viard, Buddy Pouw, Kelly Martin, Andrew Coop

Bioorg Med Chem Lett· December 2013

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Synthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities.
Jason R Healy, Padmavani Bezawada, Jihyun Shim, Jace W Jones, Maureen A Kane, Andrew Coop

ACS Chem Neurosci· September 2013

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Effect of ring-constrained phenylpropyloxyethylamines on sigma receptors.
Lidiya Stavitskaya, Michael J Seminerio, Jason R Healy, Bahar Noorbakhsh, Rae R Matsumoto, Andrew Coop

Bioorg Med Chem· September 2013

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Molecular details of the activation of the μ opioid receptor.
Jihyun Shim, Andrew Coop, Alexander D MacKerell

J Phys Chem B· July 2013

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Cholinergic modulation by opioid receptor ligands: potential application to Alzheimer's disease.
William C Motel, Andrew Coop, Christopher W Cunningham

Mini Rev Med Chem· March 2013

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Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.
Laura E McKnight, E Prabhu Raman, Padmavani Bezawada, Sucheta Kudrimoti, Paul T Wilder, Andrew Coop

ACS Med Chem Lett· December 2012

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Deconstructing 14-phenylpropyloxymetopon: minimal requirements for binding to mu opioid receptors.
Lidiya Stavitskaya, Jihyun Shim, Jason R Healy, Rae R Matsumoto, Alexander D MacKerell, Andrew Coop

Bioorg Med Chem· July 2012

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AC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells.
Nidhi Kaushal, Meenal Elliott, Matthew J Robson, Anand Krishnan V Iyer, Yon Rojanasakul, Andrew Coop

Mol Pharmacol· March 2012

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Effects of the selective sigma receptor ligand, 1-(2-phenethyl)piperidine oxalate (AC927), on the behavioral and toxic effects of cocaine.
Rae R Matsumoto, Su-Min Li, Jonathan L Katz, William E Fantegrossi, Andrew Coop

Drug Alcohol Depend· October 2011

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Consensus 3D model of μ-opioid receptor ligand efficacy based on a quantitative Conformationally Sampled Pharmacophore.
Jihyun Shim, Andrew Coop, Alexander D MacKerell

J Phys Chem B· June 2011

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Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice.
Michael J Seminerio, Nidhi Kaushal, Jamaluddin Shaikh, Jason D Huber, Andrew Coop

Pharmacol Biochem Behav· March 2011

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In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.
Paul T Wilder, Thomas H Charpentier, Melissa A Liriano, Kira Gianni, Kristen M Varney, Andrew Coop

Int J High Throughput Screen· July 2010

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