Publications by authors named "Mario D Aceto"

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MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys.
Mario D Aceto, Louis S Harris, S Stevens Negus, Matthew L Banks, Larry D Hughes

Int J Med Chem· May 2015

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Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor.
Tanila Ben Haddou, Davide Malfacini, Girolamo Calo, Mario D Aceto, Louis S Harris

Mol Pain· July 2014

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l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice.
Laura E Wise, Ishani D Premaratne, Thomas F Gamage, Aron H Lichtman, Larry D Hughes, Mario D Aceto

Pharmacol Biochem Behav· December 2012

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Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversible μ opioid receptor antagonist effects.
Humphrey A Moynihan, Ian Derrick, Jillian H Broadbear, Benjamin M Greedy, Mario D Aceto

J Med Chem· November 2012

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Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines.
Gerta Cami-Kobeci, Adrian P Neal, Faye A Bradbury, Lauren C Purington, Mario D Aceto

J Med Chem· March 2009

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The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans.
Matthew D Metcalf, Mario D Aceto, Louis S Harris, James H Woods, John R Traynor

Bioorg Med Chem· January 2008

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Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands.
David Rennison, Adrian P Neal, Gerta Cami-Kobeci, Mario D Aceto, Fernando Martinez-Bermejo

J Med Chem· October 2007

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Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
Anne-Cécile Hiebel, Yong Sok Lee, Edward Bilsky, Denise Giuvelis, Jeffrey R Deschamps, Mario D Aceto

J Med Chem· August 2007

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Pharmacological studies with a nonpeptidic, delta-opioid (-)-(1R,5R,9R)-5,9-dimethyl-2'-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride ((-)-NIH 11082).
Mario D Aceto, Everette L May, Louis S Harris, Edward R Bowman, Charles D Cook

Eur J Pharmacol· July 2007

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NIH 11082 produces anti-depressant-like activity in the mouse tail-suspension test through a delta-opioid receptor mechanism of action.
Pattipati S Naidu, Aron H Lichtman, Carey C Archer, Everett L May, Louis S Harris, Mario D Aceto

Eur J Pharmacol· July 2007

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Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
Kejun Cheng, In Jong Kim, Mei-Jing Lee, Steven A Adah, Tyler J Raymond, Mario D Aceto

Org Biomol Chem· April 2007

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Effects of JDTic, a selective kappa-opioid receptor antagonist, on the development and expression of physical dependence on morphine using a rat continuous-infusion model.
F Ivy Carroll, Louis S Harris, Mario D Aceto

Eur J Pharmacol· November 2005

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Effect of a 6-cyano substituent in 14-oxygenated N-methylmorphinans on opioid receptor binding and antinociceptive potency.
Mariana Spetea, Elisabeth Greiner, Mario D Aceto, Louis S Harris, Andrew Coop

J Med Chem· July 2005

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BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.
Stephen M Husbands, Claire L Neilan, Jillian Broadbear, Peter Grundt, Simon Breeden, Mario D Aceto

Eur J Pharmacol· February 2005

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Effects of substitution on the pyrrole N atom in derivatives of tetrahydronaltrindole, tetrahydrooxymorphindole, and a related 4,5-epoxyphenylpyrrolomorphinan.
Sanjay K Srivastava, Shefali Shefali, Carl N Miller, Mario D Aceto, John R Traynor

J Med Chem· December 2004

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Pharmacological properties of JDTic: a novel kappa-opioid receptor antagonist.
Ivy Carroll, James B Thomas, Linda A Dykstra, Arthur L Granger, Richard M Allen, Mario D Aceto

Eur J Pharmacol· October 2004

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Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.
Claire L Neilan, Stephen M Husbands, Simon Breeden, M C Holden Ko, Mario D Aceto

Eur J Pharmacol· September 2004

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Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys.
Patrick M Beardsley, Mario D Aceto, Charles D Cook, Edward R Bowman, Jennifer L Newman

Exp Clin Psychopharmacol· August 2004

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Synthesis and biological evaluation of 14-alkoxymorphinans. 21. Novel 4-alkoxy and 14-phenylpropoxy derivatives of the mu opioid receptor antagonist cyprodime.
Mariana Spetea, Falko Schüllner, Radu C Moisa, Ilona P Berzetei-Gurske, Barbara Schraml, Mario D Aceto

J Med Chem· June 2004

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Synthesis and biological evaluation of 14-alkoxymorphinans. 20. 14-phenylpropoxymetopon: an extremely powerful analgesic.
Johannes Schütz, Mariana Spetea, Martin Koch, Mario D Aceto, Louis S Harris

J Med Chem· September 2003

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N-(trifluoromethyl)benzyl substituted N-normetazocines and N-norketobemidones.
Everette L May, Andrew Coop, James H Woods, Mario D Aceto, Edward R Bowman

Bioorg Med Chem· January 2003

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The effects of delta9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors.
Christopher S Breivogel, Susan M Scates, Irina O Beletskaya, Olivia B Lowery, Mario D Aceto

Eur J Pharmacol· January 2003

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Effects of the putative antagonist NCS382 on the behavioral pharmacological actions of gammahydroxybutyrate in mice.
Charles D Cook, Mario D Aceto, Andrew Coop, Patrick M Beardsley

Psychopharmacology (Berl)· February 2002

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4'-Arylpyrrolomorphinans: effect of a pyrrolo-N-benzyl substituent in enhancing delta-opioid antagonist activity.
Sanjay K Srivastava, Stephen M Husbands, Mario D Aceto, Carl N Miller, John R Traynor

J Med Chem· January 2002

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