Publications by authors named "Andrew D Miranker"

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African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer's-like Activation.
Bianca R P Brown, Xiaoting Li, Monica R Grasty, Isabel R Lopez, Sara Dzigurski, Andrew D Miranker

bioRxiv· October 2025

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Data Sanitization to Reduce Private Information Leakage from Functional Genomics.
Gamze Gürsoy, Prashant Emani, Charlotte M Brannon, Otto A Jolanki, Arif Harmanci, Andrew D Miranker

Cell· November 2020

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Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands.
Sławomir Wójcik, Melissa Birol, Elizabeth Rhoades, Andrew D Miranker, Zachary A Levine

Methods Enzymol· July 2019

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Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Melissa Birol, Slawomir P Wojcik, Andrew D Miranker, Elizabeth Rhoades

PLoS Biol· June 2019

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Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Melissa Birol, Sunil Kumar, Elizabeth Rhoades, Andrew D Miranker

Nat Commun· April 2018

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Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
Sunil Kumar, Melissa Birol, Andrew D Miranker

Chem Commun (Camb)· May 2016

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Foldamer-mediated manipulation of a pre-amyloid toxin.
Sunil Kumar, Melissa Birol, Diana E Schlamadinger, Slawomir P Wojcik, Elizabeth Rhoades, Andrew D Miranker

Nat Commun· April 2016

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A solenoid design for assessing determinants of parallel β-sheet registration.
Ellen M White, Andrew D Miranker

Protein Eng Des Sel· December 2015

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Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry.
Jacob Witten, Amy Ruschak, Timothy Poterba, Alexis Jaramillo, Andrew D Miranker

J Phys Chem B· August 2015

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Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity.
Abhinav Nath, Diana E Schlamadinger, Elizabeth Rhoades, Andrew D Miranker

Biochemistry· June 2015

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Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics.
Sunil Kumar, Diana E Schlamadinger, Mark A Brown, Joanna M Dunn, Brandon Mercado, Andrew D Miranker

Chem Biol· March 2015

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Peptide amyloid surface display.
Marisa A Rubio, Diana E Schlamadinger, Ellen M White, Andrew D Miranker

Biochemistry· February 2015

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Fiber-dependent and -independent toxicity of islet amyloid polypeptide.
Diana E Schlamadinger, Andrew D Miranker

Biophys J· December 2014

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Small molecule screening in context: lipid-catalyzed amyloid formation.
James A Hebda, Mazin Magzoub, Andrew D Miranker

Protein Sci· October 2014

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Folded small molecule manipulation of islet amyloid polypeptide.
Sunil Kumar, Mark A Brown, Abhinav Nath, Andrew D Miranker

Chem Biol· June 2014

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A common landscape for membrane-active peptides.
Nicholas B Last, Diana E Schlamadinger, Andrew D Miranker

Protein Sci· July 2013

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A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide.
Sunil Kumar, Andrew D Miranker

Chem Commun (Camb)· May 2013

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Common mechanism unites membrane poration by amyloid and antimicrobial peptides.
Nicholas B Last, Andrew D Miranker

Proc Natl Acad Sci U S A· April 2013

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Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide.
Mazin Magzoub, Andrew D Miranker

FASEB J· March 2012

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A membrane-bound antiparallel dimer of rat islet amyloid polypeptide.
Abhinav Nath, Andrew D Miranker, Elizabeth Rhoades

Angew Chem Int Ed Engl· November 2011

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Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity.
Nicholas B Last, Elizabeth Rhoades, Andrew D Miranker

Proc Natl Acad Sci U S A· June 2011

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Protein aggregation: p53 succumbs to peer pressure.
Mazin Magzoub, Andrew D Miranker

Nat Chem Biol· May 2011

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Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs.
Abhinav Nath, Adam J Trexler, Peter Koo, Andrew D Miranker, William M Atkins

Methods Enzymol· September 2010

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Protein-induced photophysical changes to the amyloid indicator dye thioflavin T.
Leslie S Wolfe, Matthew F Calabrese, Abhinav Nath, Dorottya V Blaho, Andrew D Miranker

Proc Natl Acad Sci U S A· September 2010

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Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation.
Ishu Saraogi, James A Hebda, Jorge Becerril, Lara A Estroff, Andrew D Miranker

Angew Chem Int Ed Engl· April 2010

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