Publications by authors named "Andrew Greenstein"

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confers resistance to antiandrogens: mechanism and therapeutic implications.
Arunachalam Sekar, Rishita Chatterjee, Boobash Raj Selvadurai, Lipika R Pal, Aakanksha Verma, Andrew E Greenstein

bioRxiv· January 2025

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Relacorilant + Nab-Paclitaxel in Patients With Recurrent, Platinum-Resistant Ovarian Cancer: A Three-Arm, Randomized, Controlled, Open-Label Phase II Study.
Nicoletta Colombo, Toon Van Gorp, Ursula A Matulonis, Ana Oaknin, Rachel N Grisham, Andrew E Greenstein

J Clin Oncol· October 2023

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The glucocorticoid receptor modulator relacorilant reverses the immunosuppressive effects of cortisol.
Andrew E Greenstein, Hazel J Hunt

Int Immunopharmacol· July 2023

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Genetically engineered human pituitary corticotroph tumor organoids exhibit divergent responses to glucocorticoid receptor modulators.
Saptarshi Mallick, Jayati Chakrabarti, Jennifer Eschbacher, Andreas G Moraitis, Andrew E Greenstein

Transl Res· June 2023

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Characterization of Active MMP9 in Chronic Inflammatory Diseases Using a Novel Anti-MMP9 Antibody.
Maile Velasquez, Chris O'Sullivan, Robert Brockett, Amanda Mikels-Vigdal, Igor Mikaelian, Andrew E Greenstein

Antibodies (Basel)· January 2023

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Evaluation of the matrix metalloproteinase 9 (MMP9) inhibitor Andecaliximab as an Anti-invasive therapeutic in Head and neck squamous cell carcinoma.
Jessica L Allen, River A Hames, Natalie M Mastroianni, Andrew E Greenstein, Scott A Weed

Oral Oncol· September 2022

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Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors.
Pamela N Munster, Andrew E Greenstein, Gini F Fleming, Erkut Borazanci, Manish R Sharma

Clin Cancer Res· August 2022

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Adrenal tumors provide insight into the role of cortisol in NK cell activity.
Andrew E Greenstein, Mouhammed Amir Habra, Subhagya A Wadekar, Andreas Grauer

Endocr Relat Cancer· June 2021

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An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model.
Gheed Al-Hity, FengWei Yang, Eduard Campillo-Funollet, Andrew E Greenstein, Hazel Hunt

Commun Biol· June 2021

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Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells.
Andrew E Greenstein, Hazel J Hunt

Oncotarget· June 2021

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The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment.
Stephen G Gaffney, Elizabeth B Perry, Ping-Min Chen, Andrew Greenstein, Susan M Kaech

Oncotarget· July 2019

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MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors.
Vladi Juric, Chris O'Sullivan, Erin Stefanutti, Maria Kovalenko, Andrew Greenstein

PLoS One· April 2019

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MMP (Matrix Metalloprotease)-9-Producing Monocytes Enable T Cells to Invade the Vessel Wall and Cause Vasculitis.
Ryu Watanabe, Toshihisa Maeda, Hui Zhang, Gerald J Berry, Markus Zeisbrich, Andrew E Greenstein

Circ Res· August 2018

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Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C.
Vincent L Cannataro, Stephen G Gaffney, Carly Stender, Zi-Ming Zhao, Mark Philips, Andrew E Greenstein

Oncogene· May 2018

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Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
Todd C Appleby, Andrew E Greenstein, Magdeleine Hung, Albert Liclican, Maile Velasquez

J Biol Chem· April 2017

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Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.
Susan B Liu, Naoki Ikenaga, Zhen-Wei Peng, Deanna Y Sverdlov, Andrew Greenstein

FASEB J· April 2016

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Development and application of a fast, reproducible assay to measure HCV NS3 protease activity using Escherichia coli lysate.
Bin Han, Hadas Dvory-Sobol, Andrew Greenstein, Joseph F McCarville, Magdeleine Hung

J Virol Methods· December 2015

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Hepatitis C viral entry inhibitors prolong viral suppression by replication inhibitors in persistently-infected Huh7 cultures.
Caroline O Bush, Andrew E Greenstein, William E Delaney, Rudolf K F Beran

PLoS One· January 2015

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Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus.
Rudolf K F Beran, Ruchi Sharma, Amoreena C Corsa, Yang Tian, Justin Golde, Andrew E Greenstein

PLoS One· July 2012

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Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals.
Margaret Robinson, Yang Tian, William E Delaney, Andrew E Greenstein

Proc Natl Acad Sci U S A· June 2011

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Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.
Maria V Pokrovskii, Caroline O Bush, Rudolf K F Beran, Margaret F Robinson, Guofeng Cheng, Andrew E Greenstein

J Virol· April 2011

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Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.
T Noelle Lombana, Nathaniel Echols, Matthew C Good, Nathan D Thomsen, Ho-Leung Ng, Andrew E Greenstein

Structure· December 2010

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A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach.
Feng Yang, Jason M Robotham, Henry Grise, Stephen Frausto, Vanesa Madan, Andrew E Greenstein

PLoS Pathog· September 2010

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Novel hepatitis C virus reporter replicon cell lines enable efficient antiviral screening against genotype 1a.
Margaret Robinson, Huiling Yang, Siu-Chi Sun, Betty Peng, Yang Tian, Andrew E Greenstein

Antimicrob Agents Chemother· August 2010

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Interdomain communication in the Mycobacterium tuberculosis environmental phosphatase Rv1364c.
Andrew E Greenstein, Michal Hammel, Alexandra Cavazos, Tom Alber

J Biol Chem· October 2009

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