Publications by authors named "Andrew Harrell"

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Association of ketamine administration with intubation and cardiac arrest for prehospital patients with behavioral and substance-related complaints in the US.
Ryan Huebinger, Dorothy Habrat, Christie L Fritz, Andrew J Harrell, Whitney J Barrett

Am J Emerg Med· April 2025

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Consensus Guideline for Care of Patients in the Prehospital and Aerospace Settings with Exposures to Hydrazine and Hydrazine Derivatives.
Joshua B Gaither, Robert French, Mary Knotts, Milton Lerman, Andrew J Harrell

Prehosp Emerg Care· January 2025

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Endeavours made by trade associations, pharmaceutical companies and regulators in the replacement, reduction and refinement of animal experimentation in safety testing of pharmaceuticals.
Andrew W Harrell, Kirsty Reid, John Vahle, Frederic Brouta, Mario Beilmann

Regul Toxicol Pharmacol· September 2024

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Implementing Tourniquet Conversion Guidelines for Civilian EMS and Prehospital Organizations : A Case Report and Review.
Colin H Standifird, Sean Kaisler, Hunter Triplett, Michael J Lauria, Andrew D Fisher, Andrew J Harrell

Wilderness Environ Med· June 2024

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Cyanide Trapping of Iminium Ion Reactive Metabolites: Implications for Clinical Hepatotoxicity.
Xiusheng Miao, Gordon J Dear, Claire Beaumont, Giovanni Vitulli, Gary Collins, Andrew W Harrell

Chem Res Toxicol· May 2024

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Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption.
Neil A Miller, Rebecca H Graves, Chris D Edwards, Augustin Amour, Ed Taylor, Andrew W Harrell

Clin Pharmacokinet· February 2022

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Clinical Care and Restraint of Agitated or Combative Patients by Emergency Medical Services Practitioners.
Douglas F Kupas, Gerald C Wydro, David K Tan, Richard Kamin, Andrew J Harrell

Prehosp Emerg Care· September 2021

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Utilising Magnetically Isolated Lysosomes for Direct Quantification of Intralysosomal Drug Concentrations by LC-MS/MS Analysis: An Investigatory Study With Imipramine.
Laura Francis, Andrew Harrell, David Hallifax, Aleksandra Galetin

J Pharm Sci· September 2020

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Effect of tranexamic acid administration time on blood product use in urban trauma patients.
Elizabeth Tencza, Andrew J Harrell, Preeyaporn Sarangarm

Am J Health Syst Pharm· May 2020

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Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations.
Aarti Patel, Robert Wilson, Andrew W Harrell, Kunal S Taskar, Maxine Taylor

Drug Metab Dispos· April 2020

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A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study.
Etienne F Dumont, Amanda J Oliver, Chris Ioannou, Julia Billiard, Jeremy Dennison, Andrew W Harrell

Antimicrob Agents Chemother· April 2020

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An Innovative Approach to Characterize Clinical ADME and Pharmacokinetics of the Inhaled Drug Nemiralisib Using an Intravenous Microtracer Combined with an Inhaled Dose and an Oral Radiolabel Dose in Healthy Male Subjects.
Andrew W Harrell, Robert Wilson, Yau Lun Man, Kylie Riddell, Emily Jarvis

Drug Metab Dispos· December 2019

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Translation of Inhaled Drug Optimization Strategies into Clinical Pharmacokinetics and Pharmacodynamics Using GSK2292767A, a Novel Inhaled Phosphoinositide 3-Kinase Inhibitor.
Malcolm Begg, Chris D Edwards, J Nicole Hamblin, Eleni Pefani, Robert Wilson, Andrew Harrell

J Pharmacol Exp Ther· June 2019

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Multi-Patient Rabies Exposure on a Colorado River Rafting Expedition: Urgent vs. Emergent Transport Decision Making in an Austere Setting.
Emily A Pearce, Aaron N Farney, Laura Banks, Andrew J Harrell

Prehosp Emerg Care· March 2019

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Observational Study of Grand Canyon Rim-to-Rim Day Hikers: Determining Behavior Patterns to Aid in Preventive Search and Rescue Efforts.
Emily A Pearce, Lucie Jelínková, Lynne Fullerton, Christian J Malcolm, Hannah L Heinrich, Andrew J Harrell

Wilderness Environ Med· March 2019

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Observational Multicenter Study of a Direct-to-CT Protocol for EMS-transported Patients with Suspected Stroke.
David C Cone, Craig Cooley, Jeffrey Ferguson, Andrew J Harrell, Jeffrey H Luk

Prehosp Emerg Care· January 2019

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Improving Outcomes After Out-of-Hospital Cardiac Arrest.
Terence Valenzuela, Andrew J Harrell, Graham Nichol

JAMA Cardiol· November 2017

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Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules.
Andrew W Harrell, Caroline Sychterz, May Y Ho, Andrew Weber, Klara Valko

Pharmacol Res Perspect· October 2015

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Development of a novel remote-controlled and self-contained audiovisual-aided interactive system for immobilizing claustrophobic patients.
Harang Ju, Siyong Kim, Paul Read, Daniel Trifiletti, Andrew Harrell

J Appl Clin Med Phys· May 2015

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Integrative Treatment of Pediatric Obesity: Psychological and Spiritual Considerations.
Jennifer A Boisvert, W Andrew Harrell

Integr Med (Encinitas)· February 2015

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The impact of spirituality on eating disorder symptomatology in ethnically diverse Canadian women.
Jennifer A Boisvert, W Andrew Harrell

Int J Soc Psychiatry· December 2013

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Metabolism and disposition of vilanterol, a long-acting β(2)-adrenoceptor agonist for inhalation use in humans.
Andrew W Harrell, Sarah K Siederer, Jo Bal, Nainesh H Patel, Graeme C Young

Drug Metab Dispos· January 2013

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Disaster mitigation: initial response.
George Kennedy, Michael Richards, Michael Chicarelli, Amy Ernst, Andrew Harrell

South Med J· January 2013

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Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Melanie Z Sakatis, Melinda J Reese, Andrew W Harrell, Maxine A Taylor, Ian A Baines

Chem Res Toxicol· October 2012

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An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development.
Melinda Reese, Melanie Sakatis, Jeffrey Ambroso, Andrew Harrell, Eric Yang

Chem Biol Interact· June 2011

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