Publications by authors named "Andrew Iwanowicz"

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ESC derived human cortical neurons harboring the NACC1 c.892C > T p.R298W missense mutation exhibit molecular differences from controls that influence neuronal maturation.
Mark Deehan, Ellen Sapp, Andrew Iwanowicz, Josine Kothuis, Elizabeth Weisman

Hum Mol Genet· October 2025

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Intrastriatal Delivery of a Zinc Finger Protein Targeting the Mutant HTT Gene Allele Obviates Lipid Phenotypes in Brain and Plasma in Huntington's Disease Mice.
Andrew Iwanowicz, Adel Boudi, Connor Seeley, Ellen Sapp, Rachael Miller

Hum Gene Ther· August 2025

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Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregation.
Ellen Sapp, Adel Boudi, Andrew Iwanowicz, Jillian Belgrad, Rachael Miller

Brain Commun· August 2025

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Mutant Huntingtin exon1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MSH3 silencing, and aggregation.
Ellen Sapp, Adel Boudi, Andrew Iwanowicz, Jillian Belgrad, Rachael Miller

bioRxiv· June 2025

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Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome.
Mark F Mabanglo, Keith S Wong, Marim M Barghash, Elisa Leung, Stephanie H W Chuang, Andrew A Iwanowicz, Edwin J Iwanowicz

Structure· February 2023

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Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP.
Emily M J Fennell, Lucas J Aponte-Collazo, Joshua D Wynn, Kristina Drizyte-Miller, Elisa Leung, Andrew A Iwanowicz, Edwin J Iwanowicz

Pharmacol Res Perspect· August 2022

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