Publications by authors named "Connor Seeley"

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ESC derived human cortical neurons harboring the NACC1 c.892C > T p.R298W missense mutation exhibit molecular differences from controls that influence neuronal maturation.
Mark Deehan, Ellen Sapp, Andrew Iwanowicz, Josine Kothuis, Elizabeth Weisman, Connor Seeley

Hum Mol Genet· October 2025

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Intrastriatal Delivery of a Zinc Finger Protein Targeting the Mutant HTT Gene Allele Obviates Lipid Phenotypes in Brain and Plasma in Huntington's Disease Mice.
Andrew Iwanowicz, Adel Boudi, Connor Seeley, Ellen Sapp, Rachael Miller

Hum Gene Ther· August 2025

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Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction.
Mark A Deehan, Josine M Kothuis, Ellen Sapp, Kathryn Chase, Yuting Ke, Connor Seeley

J Neurosci· April 2024

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Early whole-body mutant huntingtin lowering averts changes in proteins and lipids important for synapse function and white matter maintenance in the LacQ140 mouse model.
Kai Shing, Ellen Sapp, Adel Boudi, Sophia Liu, Connor Seeley

Neurobiol Dis· October 2023

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Early whole-body mutant huntingtin lowering averts changes in proteins and lipids important for synapse function and white matter maintenance in the LacQ140 mouse model.
Kai Shing, Ellen Sapp, Adel Boudi, Sophia Liu, Connor Seeley

bioRxiv· July 2023

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Taming the Huntington's Disease Proteome: What Have We Learned?
Connor Seeley, Kimberly B Kegel-Gleason

J Huntingtons Dis· December 2021

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Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum.
Maria Iuliano, Connor Seeley, Ellen Sapp, Erin L Jones, Callie Martin

Front Synaptic Neurosci· March 2021

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Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region.
Ellen Sapp, Connor Seeley, Maria Iuliano, Elizabeth Weisman, Petr Vodicka

Neurobiol Dis· July 2020

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