Publications by authors named "Andrew Jezewski"

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Second generation repurposing of phenothiazine antipsychotic drugs as antifungal lead molecules via optimization of phenoxazine derivatives.
Soumitra Guin, Kathryn M Alden, Emily Harshbarger, Laurie C Ristow, Andrew J Jezewski

Eur J Med Chem· January 2026

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Synthesis and evaluation of acyl-AMP phosphate isosteres as inhibitors of fungal acetyl CoA synthetase.
Drashti G Daraji, Andrew J Jezewski, Katy M Alden, Jonah P Propp, Michael E Heene

Bioorg Med Chem Lett· December 2025

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adapts to host CO concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasis.
Laura C Ristow, Emma E Blackburn, Andrew J Jezewski, Xiaorong Lin, Damian J Krysan

bioRxiv· November 2025

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Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor.
Andrew J Jezewski, Katy M Alden, Jonah Propp, Drashti G Daraji, Charles L Lail

Nat Commun· October 2025

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Discovery and mechanism of a highly selective, antifungal acetyl CoA synthetase inhibitor.
Andrew J Jezewski, Katy M Alden, Drashti G Daraji, Charles L Lail, Jonah Propp

Res Sq· January 2025

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A single Leishmania adenylate-forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA.
Andrew J Jezewski, Taiwo E Esan, Jonah Propp, Andrew J Fuller, Drashti G Daraji

J Biol Chem· November 2024

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Survival in macrophages induces enhanced virulence in .
Jacquelyn A Nielson, Andrew J Jezewski, Melanie Wellington, J Muse Davis

mSphere· January 2024

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Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry.
Laura C Ristow, Andrew J Jezewski, Benjamin J Chadwick, Mark A Stamnes, Xiaorong Lin

Nat Commun· October 2023

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The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition.
Marion Vanneste, Anita Venzke, Soumitra Guin, Andrew J Fuller, Andrew J Jezewski

Front Oncol· October 2023

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Carbon Dioxide Potentiates Flucytosine Susceptibility in Cryptococcus neoformans.
Andrew J Jezewski, Laura C Ristow, Damian J Krysan

Microbiol Spectr· January 2023

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GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites.
Andrew J Jezewski, Ann M Guggisberg, Dana M Hodge, Naomi Ghebremichael, Gavin Nicholas John

PLoS Pathog· September 2022

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Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection.
Katy M Alden, Andrew J Jezewski, Sarah R Beattie, David Fox, Damian J Krysan

mBio· August 2022

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Is Required for Cryptococcus neoformans Fitness : Application of Copper-Regulated Gene Expression to Mouse Models of Cryptococcosis.
Sarah R Beattie, Andrew J Jezewski, Laura C Ristow, Melanie Wellington, Damian J Krysan

mSphere· June 2022

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Gluconate Kinase Is Required for Gluconate Assimilation and Sporulation in Cryptococcus neoformans.
Andrew J Jezewski, Sarah R Beattie, Katy M Alden, Damian J Krysan

Microbiol Spectr· April 2022

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Genetic analysis of Hsp90 function in Cryptococcus neoformans highlights key roles in stress tolerance and virulence.
Ci Fu, Sarah R Beattie, Andrew J Jezewski, Nicole Robbins, Luke Whitesell

Genetics· January 2022

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Targeting Host Glycolysis as a Strategy for Antimalarial Development.
Andrew J Jezewski, Yu-Hsi Lin, Julie A Reisz, Rachel Culp-Hill, Yasaman Barekatain

Front Cell Infect Microbiol· October 2021

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Structural Characterization of the Reaction and Substrate Specificity Mechanisms of Pathogenic Fungal Acetyl-CoA Synthetases.
Andrew J Jezewski, Katy M Alden, Taiwo E Esan, Nicholas D DeBouver, Jan Abendroth

ACS Chem Biol· August 2021

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Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites.
Emily S Mathews, Andrew J Jezewski, Audrey R Odom John

mBio· June 2021

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The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides.
Gillian M Fisher, Simon A Cobbold, Andrew Jezewski, Emma F Carpenter, Megan Arnold

mBio· December 2020

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Potent, specific MEPicides for treatment of zoonotic staphylococci.
Rachel L Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T Shah, Justin J Miller, Andrew J Jezewski

PLoS Pathog· June 2020

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Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites.
Ann M Guggisberg, Philip M Frasse, Andrew J Jezewski, Natasha M Kafai, Aakash Y Gandhi

mBio· November 2018

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A novel method for simulating insulin mediated GLUT4 translocation.
Andrew J Jezewski, Joshua J Larson, Beata Wysocki, Paul H Davis, Tadeusz Wysocki

Biotechnol Bioeng· December 2014

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De novo Assembly and Analysis of the Northern Leopard Frog Rana pipiens Transcriptome.
Matthew K Christenson, Andrew J Trease, Lakshmi-Prasad Potluri, Andrew J Jezewski, Vincent M Davis

J Genomics· November 2014

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