Publications by authors named "Andrew Sharff"

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Advanced exploitation of unmerged reflection data during processing and refinement with autoPROC and BUSTER.
Clemens Vonrhein, Claus Flensburg, Peter Keller, Rasmus Fogh, Andrew Sharff

Acta Crystallogr D Struct Biol· March 2024

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Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Krishna Chinthalapudi, Vinay Mandati, Jie Zheng, Andrew J Sharff, Gerard Bricogne

Nat Commun· April 2018

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Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase.
Christopher N Johnson, Valerio Berdini, Lijs Beke, Pascal Bonnet, Dirk Brehmer, Andrew Sharff

ACS Med Chem Lett· January 2015

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Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery.
Bruno Coutard, Etienne Decroly, Changqing Li, Andrew Sharff, Julien Lescar

Antiviral Res· June 2014

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Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.
Oliver S Smart, Thomas O Womack, Claus Flensburg, Peter Keller, Włodek Paciorek, Andrew Sharff

Acta Crystallogr D Biol Crystallogr· April 2012

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Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.
S D Yogesha, Andrew J Sharff, Marco Giovannini, Gerard Bricogne, Tina Izard

Protein Sci· December 2011

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Novel vinculin binding site of the IpaA invasin of Shigella.
Hajeung Park, Cesar Valencia-Gallardo, Andrew Sharff, Guy Tran Van Nhieu, Tina Izard

J Biol Chem· July 2011

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Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.
Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Andrew Sharff

PLoS Pathog· May 2011

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Data processing and analysis with the autoPROC toolbox.
Clemens Vonrhein, Claus Flensburg, Peter Keller, Andrew Sharff, Oliver Smart

Acta Crystallogr D Biol Crystallogr· April 2011

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Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody.
Marija Backovic, Rebecca M DuBois, Joseph J Cockburn, Andrew J Sharff, Marie-Christine Vaney

Proc Natl Acad Sci U S A· December 2010

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Induced-fit upon ligand binding revealed by crystal structures of the hot-dog fold thioesterase in dynemicin biosynthesis.
Chong Wai Liew, Andrew Sharff, Masayo Kotaka, Rong Kong, Huihua Sun

J Mol Biol· November 2010

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Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.
Philip Day, Andrew Sharff, Lina Parra, Anne Cleasby, Mark Williams

Acta Crystallogr D Biol Crystallogr· May 2007

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Automated protein-ligand crystallography for structure-based drug design.
Wijnand T M Mooij, Michael J Hartshorn, Ian J Tickle, Andrew J Sharff, Marcel L Verdonk

ChemMedChem· August 2006

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High-throughput protein crystallography and drug discovery.
Ian Tickle, Andrew Sharff, Mladen Vinkovic, Jeff Yon, Harren Jhoti

Chem Soc Rev· October 2004

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High-throughput crystallography to enhance drug discovery.
Andrew Sharff, Harren Jhoti

Curr Opin Chem Biol· June 2003

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