Publications by authors named "Andrew Vaughan"

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Scar wars: the viral menace.
Sara Kass-Gergi, Nicolas P Holcomb, Michael M Maiden, Laurence C Eisenlohr, Andrew E Vaughan

Am J Physiol Lung Cell Mol Physiol· November 2025

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Examining the role of Notch signaling in dysplastic lung repair.
Xinyuan Li, Madeline Singh, Andrew E Vaughan

BMC Res Notes· October 2025

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Impaired AMPK control of alveolar epithelial cell metabolism promotes pulmonary fibrosis.
Luis R Rodríguez, Konstantinos-Dionysios Alysandratos, Jeremy Katzen, Aditi Murthy, Willy Roque Barboza, Andrew E Vaughan

JCI Insight· August 2025

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Longitudinal single-cell profiles of lung regeneration after viral infection reveal persistent injury-associated cell states.
Terren K Niethamer, Joseph D Planer, Michael P Morley, Apoorva Babu, Gan Zhao, Andrew E Vaughan

Cell Stem Cell· February 2025

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Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery.
Lulu Xue, Gan Zhao, Ningqiang Gong, Xuexiang Han, Sarah J Shepherd, Andrew E Vaughan

Nat Nanotechnol· January 2025

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Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen.
Lulu Xue, Xinhong Xiong, Gan Zhao, William Molina-Arocho, Rohan Palanki, Andrew E Vaughan

J Am Chem Soc· January 2025

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Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery.
Ningqiang Gong, Wenqun Zhong, Mohamad-Gabriel Alameh, Xuexiang Han, Lulu Xue, Andrew E Vaughan

Nat Mater· December 2024

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Disruption of immune responses by type 1 diabetes exacerbates SARS-CoV-2 mediated lung injury.
Sara Kass-Gergi, Gan Zhao, Joanna Wong, Aaron I Weiner, Stephanie Adams Tzivelekidis, Andrew E Vaughan

Am J Physiol Lung Cell Mol Physiol· December 2024

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Dynamic behavior and lineage plasticity of the pulmonary venous endothelium.
Joanna Wong, Gan Zhao, Stephanie Adams-Tzivelekidis, Hongbo Wen, Prashant Chandrasekaran, Andrew E Vaughan

Nat Cardiovasc Res· December 2024

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An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung.
Dakota L Jones, Michael P Morley, Xinyuan Li, Yun Ying, Gan Zhao, Andrew E Vaughan

Science· December 2024

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Alveolar regeneration by airway secretory-cell-derived p63 progenitors.
Zan Lv, Zixin Liu, Kuo Liu, Xiuyu Lin, Wenjuan Pu, Andrew E Vaughan

Cell Stem Cell· November 2024

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Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo.
Xuexiang Han, Mohamad-Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Andrew E Vaughan

Nat Chem· October 2024

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Biomaterial-mediated intracellular control of macrophages for cell therapy in pro-inflammatory and pro-fibrotic conditions.
Tina Tylek, Joanna Wong, Andrew E Vaughan, Kara L Spiller

Biomaterials· July 2024

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Human red blood cells express the RNA sensor TLR7.
L K Metthew Lam, Emily Oatman, Kaitlyn A Eckart, Nathan J Klingensmith, Emily Flowers, Andrew E Vaughan

Sci Rep· July 2024

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Loss of Lymphatic IKKα Disrupts Lung Immune Homeostasis, Drives BALT Formation, and Protects against Influenza.
Michelle D Cully, Julianne E Nolte, Athena Patel, Andrew E Vaughan, Michael J May

Immunohorizons· July 2024

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Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation.
Gan Zhao, Maria E Gentile, Lulu Xue, Christopher V Cosgriff, Aaron I Weiner, Andrew E Vaughan

Nat Commun· May 2024

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Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis.
Luis R Rodriguez, Konstantinos-Dionysios Alysandratos, Jeremy Katzen, Aditi Murthy, Willy Roque Barboza, Andrew E Vaughan

bioRxiv· March 2024

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Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery.
Gan Zhao, Lulu Xue, Hannah C Geisler, Junchao Xu, Xinyuan Li, Andrew E Vaughan

Proc Natl Acad Sci U S A· February 2024

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In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors.
Xuexiang Han, Junchao Xu, Ying Xu, Mohamad-Gabriel Alameh, Lulu Xue, Andrew E Vaughan

Nat Commun· February 2024

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High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models.
Lulu Xue, Alex G Hamilton, Gan Zhao, Zebin Xiao, Rakan El-Mayta, Andrew E Vaughan

Nat Commun· February 2024

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An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung.
Dakota L Jones, Michael P Morley, Xinyuan Li, Yun Ying, Fabian L Cardenas-Diaz, Andrew E Vaughan

bioRxiv· February 2024

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Airway epithelial cell identity and plasticity are constrained by Sox2 during lung homeostasis, tissue regeneration, and in human disease.
Kazushige Shiraishi, Michael P Morley, Dakota L Jones, Gan Zhao, Aaron I Weiner, Andrew E Vaughan

NPJ Regen Med· January 2024

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TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue.
Gan Zhao, Lulu Xue, Aaron I Weiner, Ningqiang Gong, Stephanie Adams-Tzivelekidis, Andrew E Vaughan

Sci Transl Med· January 2024

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A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Sylvia P Thomas, Jakob M Domm, Jacob P van Vloten, Liqun Xu, Arul Vadivel, Andrew E Vaughan

Mol Ther· December 2023

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Novel genomic prognostic biomarkers for dogs with cancer.
Esther Chon, Sharadha Sakthikumar, Min Tang, Matthew J Hamilton, Andrew Vaughan

J Vet Intern Med· November 2023

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