Publications by authors named "Angela Bretz"

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Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
Dennis C Koester, Vanessa M Marx, Sarah Williams, Jan Jiricek, Maxime Dauphinais, Angela Bretz

J Med Chem· September 2022

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Pradigastat disposition in humans: in vivo and in vitro investigations.
Alana Upthagrove, Jin Chen, Charles D Meyers, Kenneth Kulmatycki, Angela Bretz

Xenobiotica· December 2017

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Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.
Dean P Phillips, Wenqi Gao, Yang Yang, Guobao Zhang, Isabelle K Lerario, Angela Bretz

J Med Chem· April 2014

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Discovery of 4-(benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4.
Hwei-Ru Tsou, Xiaoxiang Liu, Gary Birnberg, Joshua Kaplan, Mercy Otteng, Angela Bretz

J Med Chem· April 2009

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