Publications by authors named "Angela Brieger"

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Metabolic signatures of Acinetobacter baumannii and Klebsiella pneumoniae infections in acute-on-chronic liver failure.
Camilla Cadoli, Sania Arif, Wibke Ballhorn, Angela Brieger, Maximilian Joseph Brol

Cell Mol Gastroenterol Hepatol· December 2025

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DNA in acute decompensated cirrhosis: a key player in inflammation and kidney dysfunction.
Olaf Tyc, Nico Kraus, Toska Wiedemann, Hans-Peter Erasmus, Cristina Ortiz, Angela Brieger

Front Med (Lausanne)· November 2025

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CK2α Overexpression in Colorectal Cancer: Evidence for Sex- and Age-Linked Differences.
Jana Romy Friedrich, Clara Meier, Guido Plotz, Stefan Zeuzem, Angela Brieger

Cancers (Basel)· August 2025

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The role of IL-8 in cancer development and its impact on immunotherapy resistance.
Clara Meier, Angela Brieger

Eur J Cancer· March 2025

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Functional analysis of MMR gene VUS from potential Lynch syndrome patients.
Marwa Mahdouani, Drenushe Zhuri, Hazal Sezginer Guler, Dorra Hmida, Mokni Sana, Angela Brieger

PLoS One· June 2024

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Erk Inhibition as a Promising Therapeutic Strategy for High IL-8-Secreting and Low SPTAN1-Expressing Colorectal Cancer.
Clara Meier, Gianluca La Rocca, Virginia Nawrot, Beate Fißlthaler, Sarah J Overby, Jürgen Brieger, Angela Brieger

Int J Mol Sci· May 2024

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The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure.
Marcus M Mücke, Nihad El Bali, Katharina M Schwarzkopf, Frank Erhard Uschner, Nico Kraus, Angela Brieger

Int J Mol Sci· January 2024

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Key role of phosphorylation sites in ATPase domain and Linker region of MLH1 for DNA binding and functionality of MutLα.
May-Britt Firnau, Guido Plotz, Stefan Zeuzem, Angela Brieger

Sci Rep· August 2023

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A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation.
Karla Wolf, Jan Kosinski, Toby J Gibson, Nicole Wesch, Volker Dötsch, Angela Brieger

Nucleic Acids Res· July 2023

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Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure.
Robert Schierwagen, Wenyi Gu, Angela Brieger, Bernhard Brüne, Sandra Ciesek

Am J Physiol Cell Physiol· July 2023

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Functional characterization of MLH1 missense variants unveils mechanisms of pathogenicity and clarifies role in cancer.
Marwa Mahdouani, Slim Ben Ahmed, Fahmi Hmila, Henda Rais, Rihab Ben Sghaier, Angela Brieger

PLoS One· December 2022

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CK2 and the Hallmarks of Cancer.
May-Britt Firnau, Angela Brieger

Biomedicines· August 2022

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High Expression of Casein Kinase 2 Alpha Is Responsible for Enhanced Phosphorylation of DNA Mismatch Repair Protein MLH1 and Increased Tumor Mutation Rates in Colorectal Cancer.
Katharina Ulreich, May-Britt Firnau, Nina Tagscherer, Sandra Beyer, Anne Ackermann, Angela Brieger

Cancers (Basel)· March 2022

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SPTAN1 Expression Predicts Treatment and Survival Outcomes in Colorectal Cancer.
Christopher Schrecker, Sophia Behrens, Rebecca Schönherr, Anne Ackermann, Daniel Pauli, Angela Brieger

Cancers (Basel)· July 2021

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Investigation of the Wilson gene ATP7B transcriptional start site and the effect of core promoter alterations.
Clemens Höflich, Angela Brieger, Stefan Zeuzem, Guido Plotz

Sci Rep· April 2021

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Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region.
Guido Plotz, Laura A Lopez-Garcia, Angela Brieger, Stefan Zeuzem, Ricardo M Biondi

PLoS One· January 2021

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Expression and secretion of the pro‑inflammatory cytokine IL‑8 is increased in colorectal cancer cells following the knockdown of non‑erythroid spectrin αII.
Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger

Int J Oncol· June 2020

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Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.
Anne Ackermann, Christopher Schrecker, Dimitra Bon, Nicolaus Friedrichs, Katrin Bankov, Angela Brieger

PLoS One· December 2019

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The Role of Nonerythroid Spectrin II in Cancer.
Anne Ackermann, Angela Brieger

J Oncol· May 2019

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Analysis of MUTYH alternative transcript expression, promoter function, and the effect of human genetic variants.
Nicole Köger, Angela Brieger, Inga M Hinrichsen, Stefan Zeuzem, Guido Plotz

Hum Mutat· April 2019

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DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477).
Isabel M Weßbecher, Inga Hinrichsen, Sebastian Funke, Thomas Oellerich, Guido Plotz, Angela Brieger

Mol Carcinog· December 2018

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Phosphorylation meets DNA mismatch repair.
Isabel Madeleine Weßbecher, Angela Brieger

DNA Repair (Amst)· December 2018

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Evaluation of MLH1 variants of unclear significance.
Nicole Köger, Lea Paulsen, Francisco López-Kostner, Adriana Della Valle, Carlos Alberto Vaccaro, Angela Brieger

Genes Chromosomes Cancer· July 2018

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Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2.
Inga Hinrichsen, Isabel M Weßbecher, Meik Huhn, Sandra Passmann, Stefan Zeuzem, Angela Brieger

Mol Carcinog· December 2017

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Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.
Inga Hinrichsen, Anne Ackermann, Tonja Düding, Annika Graband, Natalie Filmann, Angela Brieger

Mol Carcinog· July 2017

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