Publications by authors named "Guido Plotz"

Claim this Profile
C
CK2α Overexpression in Colorectal Cancer: Evidence for Sex- and Age-Linked Differences.
Jana Romy Friedrich, Clara Meier, Guido Plotz, Stefan Zeuzem, Angela Brieger

Cancers (Basel)· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional analysis of MMR gene VUS from potential Lynch syndrome patients.
Marwa Mahdouani, Drenushe Zhuri, Hazal Sezginer Guler, Dorra Hmida, Mokni Sana, Guido Plotz

PLoS One· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Erk Inhibition as a Promising Therapeutic Strategy for High IL-8-Secreting and Low SPTAN1-Expressing Colorectal Cancer.
Clara Meier, Gianluca La Rocca, Virginia Nawrot, Beate Fißlthaler, Sarah J Overby, Guido Plotz

Int J Mol Sci· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Key role of phosphorylation sites in ATPase domain and Linker region of MLH1 for DNA binding and functionality of MutLα.
May-Britt Firnau, Guido Plotz, Stefan Zeuzem, Angela Brieger

Sci Rep· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation.
Karla Wolf, Jan Kosinski, Toby J Gibson, Nicole Wesch, Volker Dötsch, Guido Plotz

Nucleic Acids Res· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional characterization of MLH1 missense variants unveils mechanisms of pathogenicity and clarifies role in cancer.
Marwa Mahdouani, Slim Ben Ahmed, Fahmi Hmila, Henda Rais, Rihab Ben Sghaier, Guido Plotz

PLoS One· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High Expression of Casein Kinase 2 Alpha Is Responsible for Enhanced Phosphorylation of DNA Mismatch Repair Protein MLH1 and Increased Tumor Mutation Rates in Colorectal Cancer.
Katharina Ulreich, May-Britt Firnau, Nina Tagscherer, Sandra Beyer, Anne Ackermann, Guido Plotz

Cancers (Basel)· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SPTAN1 Expression Predicts Treatment and Survival Outcomes in Colorectal Cancer.
Christopher Schrecker, Sophia Behrens, Rebecca Schönherr, Anne Ackermann, Daniel Pauli, Guido Plotz

Cancers (Basel)· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigation of the Wilson gene ATP7B transcriptional start site and the effect of core promoter alterations.
Clemens Höflich, Angela Brieger, Stefan Zeuzem, Guido Plotz

Sci Rep· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region.
Guido Plotz, Laura A Lopez-Garcia, Angela Brieger, Stefan Zeuzem, Ricardo M Biondi

PLoS One· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expression and secretion of the pro‑inflammatory cytokine IL‑8 is increased in colorectal cancer cells following the knockdown of non‑erythroid spectrin αII.
Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger

Int J Oncol· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Validation of an in Vitro Mismatch Repair Assay Used in the Functional Characterization of Mismatch Repair Variants.
Maribel González-Acosta, Inga Hinrichsen, Anna Fernández, Conxi Lázaro, Marta Pineda, Guido Plotz

J Mol Diagn· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.
Anne Ackermann, Christopher Schrecker, Dimitra Bon, Nicolaus Friedrichs, Katrin Bankov, Guido Plotz

PLoS One· December 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of MUTYH alternative transcript expression, promoter function, and the effect of human genetic variants.
Nicole Köger, Angela Brieger, Inga M Hinrichsen, Stefan Zeuzem, Guido Plotz

Hum Mutat· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diagnostic yield and clinical utility of a comprehensive gene panel for hereditary tumor syndromes.
Jonas Henn, Isabel Spier, Ronja S Adam, Stefanie Holzapfel, Siegfried Uhlhaas, Guido Plotz

Hered Cancer Clin Pract· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477).
Isabel M Weßbecher, Inga Hinrichsen, Sebastian Funke, Thomas Oellerich, Guido Plotz

Mol Carcinog· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of MLH1 variants of unclear significance.
Nicole Köger, Lea Paulsen, Francisco López-Kostner, Adriana Della Valle, Carlos Alberto Vaccaro, Guido Plotz

Genes Chromosomes Cancer· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2.
Inga Hinrichsen, Isabel M Weßbecher, Meik Huhn, Sandra Passmann, Stefan Zeuzem, Guido Plotz

Mol Carcinog· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Elucidating the clinical significance of two PMS2 missense variants coexisting in a family fulfilling hereditary cancer criteria.
Maribel González-Acosta, Jesús Del Valle, Matilde Navarro, Bryony A Thompson, Sílvia Iglesias, Guido Plotz

Fam Cancer· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.
Inga Hinrichsen, Anne Ackermann, Tonja Düding, Annika Graband, Natalie Filmann, Guido Plotz

Mol Carcinog· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas.
Isabel Spier, Stefanie Holzapfel, Janine Altmüller, Bixiao Zhao, Sukanya Horpaopan, Guido Plotz

Int J Cancer· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype.
Nuria Seguí, Matilde Navarro, Marta Pineda, Nicole Köger, Fernando Bellido, Guido Plotz

Gut· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional testing strategy for coding genetic variants of unclear significance in MLH1 in Lynch syndrome diagnosis.
Inga Hinrichsen, Dieter Schäfer, Deborah Langer, Nicole Köger, Margarethe Wittmann, Guido Plotz

Carcinogenesis· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs.
Inga Hinrichsen, Matthias Kemp, Jan Peveling-Oberhag, Sandra Passmann, Guido Plotz

PLoS One· September 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1.
Inga Hinrichsen, Benjamin Philipp Ernst, Franziska Nuber, Sandra Passmann, Dieter Schäfer, Guido Plotz

Mol Cancer· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis