Publications by authors named "Angela Cree"

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Correction: Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration-the PINNACLE trial protocol.
Janice Sutton, Martin J Menten, Sophie Riedl, Hrvoje Bogunović, Oliver Leingang, Angela J Cree

Eye (Lond)· June 2023

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Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration-the PINNACLE trial protocol.
Janice Sutton, Martin J Menten, Sophie Riedl, Hrvoje Bogunović, Oliver Leingang, Angela J Cree

Eye (Lond)· April 2023

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The effect of systemic levels of TNF-alpha and complement pathway activity on outcomes of VEGF inhibition in neovascular AMD.
Adnan H Khan, Charles O Pierce, Gabriella De Salvo, Helen Griffiths, Marie Nelson, Angela J Cree

Eye (Lond)· November 2022

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An Exploratory Study Provides Insights into MMP9 and Aβ Levels in the Vitreous and Blood across Different Ages and in a Subset of AMD Patients.
Savannah A Lynn, Flavie Soubigou, Jennifer M Dewing, Amanda Smith, Joanna Ballingall, Angela Cree

Int J Mol Sci· November 2022

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Epigenetic Age Acceleration Is Not Associated with Age-Related Macular Degeneration.
Neil Saptarshi, Daniel Green, Angela Cree, Andrew Lotery, Luminita Paraoan

Int J Mol Sci· December 2021

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Prevalence and phenotype associations of complement factor I mutations in geographic atrophy.
Adnan H Khan, Janice Sutton, Angela J Cree, Samir Khandhadia, Gabriella De Salvo

Hum Mutat· September 2021

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Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.
Puya Gharahkhani, Eric Jorgenson, Pirro Hysi, Anthony P Khawaja, Sarah Pendergrass, Angela J Cree

Nat Commun· February 2021

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Oligomeric Aβ Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function.
Savannah A Lynn, David A Johnston, Jenny A Scott, Rosie Munday, Roshni S Desai, Angela J Cree

Cells· February 2021

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In vitro stem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsby fundus dystrophy.
Heidi Hongisto, Jennifer M Dewing, David Rg Christensen, Jennifer Scott, Angela J Cree

J Pathol· October 2020

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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
Pieter W M Bonnemaijer, Elisabeth M van Leeuwen, Adriana I Iglesias, Puya Gharahkhani, Veronique Vitart, Angela J Cree

Commun Biol· July 2020

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An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity.
Ayub Qassim, Emmanuelle Souzeau, Owen M Siggs, Mark M Hassall, Xikun Han, Angela J Cree

Ophthalmology· July 2020

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Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration.
Thomas M Hallam, Kevin J Marchbank, Claire L Harris, Clive Osmond, Victoria G Shuttleworth, Angela J Cree

Invest Ophthalmol Vis Sci· June 2020

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A novel, wearable, electronic visual aid to assist those with reduced peripheral vision.
Ffion E Brown, Janice Sutton, Ho M Yuen, Dylan Green, Spencer Van Dorn, Angela J Cree

PLoS One· March 2020

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Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression.
Jamie E Craig, Xikun Han, Ayub Qassim, Mark Hassall, Jessica N Cooke Bailey, Angela Jane Cree

Nat Genet· February 2020

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Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial.
Andrew Lotery, Sobha Sivaprasad, Abby O'Connell, Rosie A Harris, Lucy Culliford, Angela Cree

Lancet· January 2020

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A convenient protocol for establishing a human cell culture model of the outer retina.
Savannah A Lynn, Eloise Keeling, Jennifer M Dewing, David A Johnston, Anton Page, Angela J Cree

F1000Res· September 2019

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A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping.
Luke O'Gorman, Chelsea S Norman, Luke Michaels, Tutte Newall, Andrew H Crosby, Angela J Cree

Sci Rep· September 2019

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Clinical efficacy of eplerenone versus placebo for central serous chorioretinopathy: study protocol for the VICI randomised controlled trial.
Abby Willcox, Lucy Culliford, Lucy Ellis, Chris A Rogers, Angela Cree

Eye (Lond)· February 2019

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Comprehensive sequencing of the myocilin gene in a selected cohort of severe primary open-angle glaucoma patients.
Luke O'Gorman, Angela J Cree, Daniel Ward, Helen L Griffiths, Roshan Sood

Sci Rep· February 2019

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A Genome-Wide Complement for Central Serous Chorioretinopathy.
Rebecca Anne Kaye, Angela Jane Cree, Andrew John Lotery

JAMA Ophthalmol· October 2018

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Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration.
Laura Lorés-Motta, Moeen Riaz, Michelle Grunin, Jordi Corominas, Freekje van Asten, Angela J Cree

JAMA Ophthalmol· August 2018

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AMD Risk Alleles Are Not Implicated in Age-Related Macular Degeneration in Patients with Liver Transplantation.
Samir Khandhadia, Jane Gibson, Sarah Ennis, Angela J Cree, Andrew J Lotery

Ophthalmol Retina· August 2018

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Sorsby fundus dystrophy - A review of pathology and disease mechanisms.
David R G Christensen, Ffion E Brown, Angela J Cree, J Arjuna Ratnayaka, Andrew J Lotery

Exp Eye Res· December 2017

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Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE.
Savannah A Lynn, Gareth Ward, Eloise Keeling, Jenny A Scott, Angela J Cree

Tissue Cell· August 2017

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