Publications by authors named "Angela Goodenough"

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Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity.
Anne-Françoise Aubry, Brian Dean, Ulf Diczfalusy, Angela Goodenough, André Iffland

AAPS J· September 2016

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Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.
Audris Huang, Lata Jayaraman, Aberra Fura, Gregory D Vite, George L Trainor, Angela K Goodenough

ACS Med Chem Lett· January 2016

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Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects.
Sreeneeranj Kasichayanula, David W Boulton, Wen-Lin Luo, A David Rodrigues, Zheng Yang, Angela Goodenough

Br J Clin Pharmacol· November 2014

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Quantification of 4-beta-hydroxycholesterol in human plasma using automated sample preparation and LC-ESI-MS/MS analysis.
Angela K Goodenough, Joelle M Onorato, Zheng Ouyang, Shu Chang, A David Rodrigues

Chem Res Toxicol· September 2011

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Characterization of protein therapeutics by mass spectrometry: recent developments and future directions.
Guodong Chen, Bethanne M Warrack, Angela K Goodenough, Hui Wei, David B Wang-Iverson

Drug Discov Today· January 2011

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Four novel spirooxazacamphorsultam derivatives.
Burkhardt I Wilke, Angela K Goodenough, Cory C Bausch, Erika N Cline, M Leigh Abrams

Acta Crystallogr C· December 2010

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Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.
Erin E Bessette, Simon D Spivack, Angela K Goodenough, Tao Wang, Shailesh Pinto

Chem Res Toxicol· July 2010

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Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells.
Barbara C Spink, James A Bennett, Brian T Pentecost, Nicole Lostritto, Neal A Englert, Angela K Goodenough

Toxicol Appl Pharmacol· November 2009

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Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.
Erin E Bessette, Angela K Goodenough, Sophie Langouët, Isil Yasa, Ivan D Kozekov

Anal Chem· January 2009

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Transcription processing at 1,N2-ethenoguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase.
Alexandra Dimitri, Angela K Goodenough, F Peter Guengerich, Suse Broyde, David A Scicchitano

J Mol Biol· January 2008

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Structure of the 1,N2-etheno-2'-deoxyguanosine adduct in duplex DNA at pH 8.6.
Ganesh Shanmugam, Angela K Goodenough, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo

Chem Res Toxicol· November 2007

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Aristolochic acid and the etiology of endemic (Balkan) nephropathy.
Arthur P Grollman, Shinya Shibutani, Masaaki Moriya, Frederick Miller, Lin Wu, Angela K Goodenough

Proc Natl Acad Sci U S A· July 2007

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Identification of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline: an abundant mutagenic heterocyclic aromatic amine formed in cooked beef.
Robert J Turesky, Angela K Goodenough, Weijuan Ni, Lynn McNaughton, David M LeMaster

Chem Res Toxicol· March 2007

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Novel LC-ESI/MS/MS(n) method for the characterization and quantification of 2'-deoxyguanosine adducts of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by 2-D linear quadrupole ion trap mass spectrometry.
Angela K Goodenough, Herman A J Schut, Robert J Turesky

Chem Res Toxicol· February 2007

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Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases.
Jeong-Yun Choi, Hong Zang, Karen C Angel, Ivan D Kozekov, Angela K Goodenough

Chem Res Toxicol· June 2006

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Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.
Angela K Goodenough, Ivan D Kozekov, Hong Zang, Jeong-Yun Choi, F Peter Guengerich

Chem Res Toxicol· November 2005

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DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.
Hong Zang, Angela K Goodenough, Jeong-Yun Choi, Adriana Irimia, Lioudmila V Loukachevitch

J Biol Chem· August 2005

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