Publications by authors named "Ivan D Kozekov"

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Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.
Vipender Singh, Bogdan I Fedeles, Deyu Li, James C Delaney, Ivan D Kozekov, Albena Kozekova

Chem Res Toxicol· September 2014

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Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.
Ganesh Shanmugam, Irina G Minko, Surajit Banerjee, Plamen P Christov, Ivan D Kozekov

Chem Res Toxicol· September 2013

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Replication of N2,3-ethenoguanine by DNA polymerases.
Linlin Zhao, Plamen P Christov, Ivan D Kozekov, Matthew G Pence, Pradeep S Pallan

Angew Chem Int Ed Engl· May 2012

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Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene.
Constance M Harris, Donald F Stec, Plamen P Christov, Ivan D Kozekov, Carmelo J Rizzo

Chem Res Toxicol· November 2011

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1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine.
Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone

Chem Res Toxicol· July 2011

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Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.
Ivan D Kozekov, Robert J Turesky, Guillermo R Alas, Constance M Harris, Thomas M Harris

Chem Res Toxicol· November 2010

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Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
Plamen P Christov, Katya V Petrova, Ganesh Shanmugam, Ivan D Kozekov, Albena Kozekova

Chem Res Toxicol· August 2010

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DNA cross-link induced by trans-4-hydroxynonenal.
Hai Huang, Ivan D Kozekov, Albena Kozekova, Hao Wang, R Stephen Lloyd

Environ Mol Mutagen· July 2010

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Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage.
Hai Huang, Ivan D Kozekov, Albena Kozekova, Carmelo J Rizzo, Amanda K McCullough

Biochemistry· July 2010

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Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links.
Kinrin Yamanaka, Irina G Minko, Kei-ichi Takata, Alexander Kolbanovskiy, Ivan D Kozekov

Chem Res Toxicol· March 2010

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Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion.
Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone

Biochemistry· March 2010

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Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.
Huidong Zhang, Urban Bren, Ivan D Kozekov, Carmelo J Rizzo, Donald F Stec

J Mol Biol· September 2009

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Checkpoint signaling from a single DNA interstrand crosslink.
Merav Ben-Yehoyada, Lily C Wang, Ivan D Kozekov, Carmelo J Rizzo, Max E Gottesman

Mol Cell· September 2009

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Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.
Hai Huang, Hye-Young Kim, Ivan D Kozekov, Young-Jin Cho, Hao Wang, Albena Kozekova

J Am Chem Soc· June 2009

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Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes.
Huidong Zhang, Robert L Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli

J Biol Chem· June 2009

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Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.
Irina G Minko, Ivan D Kozekov, Thomas M Harris, Carmelo J Rizzo, R Stephen Lloyd

Chem Res Toxicol· May 2009

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Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Huidong Zhang, Robert L Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli

J Biol Chem· February 2009

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Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.
Charles G Knutson, Emily H Rubinson, Dapo Akingbade, Carolyn S Anderson, Donald F Stec, Ivan D Kozekov

Biochemistry· February 2009

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Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.
Erin E Bessette, Angela K Goodenough, Sophie Langouët, Isil Yasa, Ivan D Kozekov

Anal Chem· January 2009

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Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine.
Plamen P Christov, Kyle L Brown, Ivan D Kozekov, Michael P Stone, Thomas M Harris

Chem Res Toxicol· December 2008

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Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.
Irina G Minko, Kinrin Yamanaka, Ivan D Kozekov, Albena Kozekova, Chiara Indiani

Chem Res Toxicol· October 2008

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The formamidopyrimidine derivative of 7-(2-oxoethyl)-2'-deoxyguanosine.
Plamen P Christov, Ivan D Kozekov, Carmelo J Rizzo, Thomas M Harris

Chem Res Toxicol· September 2008

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Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.
Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone

Chem Res Toxicol· September 2008

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Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.
Michael P Stone, Young-Jin Cho, Hai Huang, Hye-Young Kim, Ivan D Kozekov, Albena Kozekova

Acc Chem Res· July 2008

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Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links.
Irina G Minko, Michael B Harbut, Ivan D Kozekov, Albena Kozekova, Petra M Jakobs

J Biol Chem· June 2008

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