Publications by authors named "Vipender Singh"

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Structural Insights Into Tautomeric Dynamics in Nucleic Acids and in Antiviral Nucleoside Analogs.
Bogdan I Fedeles, Deyu Li, Vipender Singh

Front Mol Biosci· January 2022

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Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions.
Fangyi Chen, Ke Bian, Qi Tang, Bogdan I Fedeles, Vipender Singh

Chem Res Toxicol· April 2017

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Lewis Acid Catalyzed Annulation of Nitrones with Oxiranes, Aziridines, and Thiiranes.
Stalin R Pathipati, Vipender Singh, Lars Eriksson, Nicklas Selander

Org Lett· September 2015

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The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.
Bogdan I Fedeles, Vipender Singh, James C Delaney, Deyu Li, John M Essigmann

J Biol Chem· August 2015

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Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer.
Bogdan I Fedeles, Bret D Freudenthal, Emily Yau, Vipender Singh, Shiou-chi Chang

Proc Natl Acad Sci U S A· August 2015

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Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Shiou-chi Chang, Bogdan I Fedeles, Jie Wu, James C Delaney, Deyu Li, Vipender Singh

Nucleic Acids Res· June 2015

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Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.
Chunte Sam Peng, Bogdan I Fedeles, Vipender Singh, Deyu Li, Tiffany Amariuta

Proc Natl Acad Sci U S A· March 2015

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Role of tautomerism in RNA biochemistry.
Vipender Singh, Bogdan I Fedeles, John M Essigmann

RNA· January 2015

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Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.
Vipender Singh, Bogdan I Fedeles, Deyu Li, James C Delaney, Ivan D Kozekov

Chem Res Toxicol· September 2014

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Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine.
Deyu Li, Bogdan I Fedeles, Vipender Singh, Chunte Sam Peng, Katherine J Silvestre

Proc Natl Acad Sci U S A· August 2014

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Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch.
Vipender Singh, Chunte Sam Peng, Deyu Li, Koyel Mitra, Katherine J Silvestre

ACS Chem Biol· January 2014

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Synthesis of 1,3,5-trisubstituted pyrazolines via Zn(II)-catalyzed double hydroamination of enynes with aryl hydrazines.
Nitin T Patil, Vipender Singh

Chem Commun (Camb)· October 2011

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A two-step chemical mechanism for ribosome-catalysed peptide bond formation.
David A Hiller, Vipender Singh, Minghong Zhong, Scott A Strobel

Nature· July 2011

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Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects.
David A Hiller, Minghong Zhong, Vipender Singh, Scott A Strobel

Biochemistry· May 2010

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Transition-state structure of neisseria meningitides 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Vipender Singh, Minkui Luo, Rosemary L Brown, Gillian E Norris, Vern L Schramm

J Am Chem Soc· November 2007

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Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases.
Jemy A Gutierrez, Minkui Luo, Vipender Singh, Lei Li, Rosemary L Brown

ACS Chem Biol· November 2007

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Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases.
Minkui Luo, Vipender Singh, Erika A Taylor, Vern L Schramm

J Am Chem Soc· June 2007

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Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidase.
Vipender Singh, Vern L Schramm

J Am Chem Soc· March 2007

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Transition-state structure of human 5'-methylthioadenosine phosphorylase.
Vipender Singh, Vern L Schramm

J Am Chem Soc· November 2006

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Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Vipender Singh, Wuxian Shi, Steven C Almo, Gary B Evans, Richard H Furneaux

Biochemistry· October 2006

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Transition state structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli and its similarity to transition state analogues.
Vipender Singh, Jeffrey E Lee, Sara Núñez, P Lynne Howell, Vern L Schramm

Biochemistry· September 2005

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Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.
Gary B Evans, Richard H Furneaux, Dirk H Lenz, Gavin F Painter, Vern L Schramm, Vipender Singh

J Med Chem· July 2005

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Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Jeffrey E Lee, Vipender Singh, Gary B Evans, Peter C Tyler, Richard H Furneaux

J Biol Chem· May 2005

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Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.
Vipender Singh, Gary B Evans, Dirk H Lenz, Jennifer M Mason, Keith Clinch

J Biol Chem· May 2005

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Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.
Li-Min Ting, Wuxian Shi, Andrzej Lewandowicz, Vipender Singh, Agnes Mwakingwe

J Biol Chem· March 2005

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