Publications by authors named "Angela McCahill"

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Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.
Kongtana Trakarnsanga, Daniel Ferguson, Deborah E Daniels, Rebecca E Griffiths, Marieangela C Wilson, Angela McCahill

Stem Cell Res Ther· April 2019

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Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.
Martha Lopez-Yrigoyen, Cheng-Tao Yang, Antonella Fidanza, Luca Cassetta, A Helen Taylor, Angela McCahill

Nat Commun· February 2019

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High-Efficiency Serum-Free Feeder-Free Erythroid Differentiation of Human Pluripotent Stem Cells Using Small Molecules.
Emmanuel N Olivier, Lamin Marenah, Angela McCahill, Alison Condie, Scott Cowan

Stem Cells Transl Med· October 2016

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Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells.
Nicole M Kane, Lynsey Howard, Betty Descamps, Marco Meloni, John McClure, Angela McCahill

Stem Cells· April 2012

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Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.
Peter Burton, David R Adams, Achamma Abraham, Robert W Allcock, Zhong Jiang, Angela McCahill

Biochem J· December 2010

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Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells.
Peter Burton, David R Adams, Achamma Abraham, Robert W Allcock, Zhong Jiang, Angela McCahill

Biochem Soc Trans· August 2010

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In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10).
Angela McCahill, Lachlan Campbell, Theresa McSorley, Arvind Sood, Martin J Lynch

Cell Signal· November 2008

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1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
K John Smith, George S Baillie, Eva I Hyde, Xiang Li, Thomas M Houslay, Angela McCahill

Cell Signal· December 2007

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Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.
Graeme B Bolger, George S Baillie, Xiang Li, Martin J Lynch, Pawel Herzyk, Angela McCahill

Biochem J· August 2006

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In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
Angela McCahill, Theresa McSorley, Elaine Huston, Elaine V Hill, Martin J Lynch

Cell Signal· September 2005

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The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.
Graeme B Bolger, Angela McCahill, Elaine Huston, York-Fong Cheung, Theresa McSorley

J Biol Chem· December 2003

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The RACK1 scaffold protein: a dynamic cog in cell response mechanisms.
Angela McCahill, Jim Warwicker, Graeme B Bolger, Miles D Houslay, Stephen J Yarwood

Mol Pharmacol· December 2002

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Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.
Graeme B Bolger, Angela McCahill, Stephen J Yarwood, Michael R Steele, Jim Warwicker

BMC Biochem· August 2002

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