Publications by authors named "Angelo Lombardo"

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Role of S1PR1 in Modulating Airway Epithelial Responses to in Cystic Fibrosis.
Cristina Cigana, Claudia Caslini, Alessandro Migliara, Beatriz Alcala'-Franco, Laura Veschetti, Angelo Lombardo

Pathogens· November 2025

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A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels.
Frederic Tremblay, Qiang Xiong, Shrijal S Shah, Chih-Wei Ko, Kenneth Kelly, Angelo Lombardo

Nat Med· April 2025

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Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose.
Janin Germer, Anna-Lina Lessl, Jana Pöhmerer, Melina Grau, Eric Weidinger, Angelo Lombardo

J Control Release· June 2024

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IL-10-Engineered Human CD4 Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism.
Grazia Locafaro, Grazia Andolfi, Fabio Russo, Luca Cesana, Antonello Spinelli, Angelo Lombardo

Mol Ther· March 2024

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Durable and efficient gene silencing in vivo by hit-and-run epigenome editing.
Martino Alfredo Cappelluti, Valeria Mollica Poeta, Sara Valsoni, Piergiuseppe Quarato, Simone Merlin, Angelo Lombardo

Nature· March 2024

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miR-126 identifies a quiescent and chemo-resistant human B-ALL cell subset that correlates with minimal residual disease.
Carolina Caserta, Silvia Nucera, Matteo Barcella, Grazia Fazio, Matteo Maria Naldini, Angelo Lombardo

Leukemia· October 2023

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In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing.
Alessandro Migliara, Martino Alfredo Cappelluti, Francesca Giannese, Sara Valsoni, Alberto Coglot, Angelo Lombardo

J Vis Exp· May 2023

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Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I iPSCs for β cell replacement.
Raniero Chimienti, Tania Baccega, Silvia Torchio, Fabio Manenti, Silvia Pellegrini, Marta Tiffany Lombardo, Angelo Lombardo

Cell Rep· September 2022

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DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes.
Anna Maria Sole Giordano, Marco Luciani, Francesca Gatto, Monah Abou Alezz, Chiara Beghè, Angelo Lombardo

J Exp Med· April 2022

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Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene.
Benedetta M Santoliquido, Michela Frenquelli, Claudia Contadini, Stefano Bestetti, Marco Gaviraghi, Angelo Lombardo

Life Sci Alliance· August 2021

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Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency.
Matteo Zoccolillo, Immacolata Brigida, Federica Barzaghi, Serena Scala, Raisa Jofra Hernández, Angelo Lombardo

Blood Adv· August 2021

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Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis.
Sara Caputo, Matteo Grioni, Chiara S Brambillasca, Antonella Monno, Arianna Brevi, Angelo Lombardo

Front Immunol· April 2021

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Altered Cl homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability.
Andrea Maset, Luisa Galla, Simona Francia, Olga Cozzolino, Paola Capasso, Angelo Lombardo

Proc Natl Acad Sci U S A· January 2021

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Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced and Genetic Engineering.
Monica Soldi, Lucia Sergi Sergi, Giulia Unali, Thomas Kerzel, Ivan Cuccovillo, Angelo Lombardo

Mol Ther Methods Clin Dev· December 2020

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Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches.
Ileana Bortolomai, Monica Sandri, Elena Draghici, Elena Fontana, Elisabetta Campodoni, Angelo Lombardo

Stem Cells Transl Med· October 2019

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Patient-Specific iPSC-Derived Endothelial Cells Provide Long-Term Phenotypic Correction of Hemophilia A.
Cristina Olgasi, Maria Talmon, Simone Merlin, Alessia Cucci, Yvonne Richaud-Patin, Angelo Lombardo

Stem Cell Reports· December 2018

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T-cell defects in patients with germline mutations account for combined immunodeficiency.
Immacolata Brigida, Matteo Zoccolillo, Maria Pia Cicalese, Laurène Pfajfer, Federica Barzaghi, Angelo Lombardo

Blood· November 2018

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Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.
Sara Benedetti, Narumi Uno, Hidetoshi Hoshiya, Martina Ragazzi, Giulia Ferrari, Angelo Lombardo

EMBO Mol Med· February 2018

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Genome editing for scalable production of alloantigen-free lentiviral vectors for gene therapy.
Michela Milani, Andrea Annoni, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Angelo Lombardo

EMBO Mol Med· November 2017

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Therapeutic gene editing in CD34 hematopoietic progenitors from Fanconi anemia patients.
Begoña Diez, Pietro Genovese, Francisco J Roman-Rodriguez, Lara Alvarez, Giulia Schiroli, Angelo Lombardo

EMBO Mol Med· November 2017

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IL-10-Engineered Human CD4 Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism.
Grazia Locafaro, Grazia Andolfi, Fabio Russo, Luca Cesana, Antonello Spinelli, Angelo Lombardo

Mol Ther· October 2017

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Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.
Giulia Schiroli, Samuele Ferrari, Anthony Conway, Aurelien Jacob, Valentina Capo, Angelo Lombardo

Sci Transl Med· October 2017

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NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.
Sara Mastaglio, Pietro Genovese, Zulma Magnani, Eliana Ruggiero, Elisa Landoni, Angelo Lombardo

Blood· August 2017

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Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing.
Angelo Amabile, Alessandro Migliara, Paola Capasso, Mauro Biffi, Davide Cittaro, Angelo Lombardo

Cell· September 2016

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Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis.
Lucia Cottone, Annalisa Capobianco, Chiara Gualteroni, Antonella Monno, Isabella Raccagni, Angelo Lombardo

Oncoimmunology· May 2016

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