Publications by authors named "Anilkumar Gopalakrishnapillai"

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Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway.
Denggang Fu, Hua Jiang, Alan Long, Ella Harris, Hongfen Guo, Anilkumar Gopalakrishnapillai

Nat Commun· July 2025

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ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche.
Hua Jiang, Denggang Fu, Santhosh Kumar Pasupuleti, Baskar Ramdas, Alan Long, Anilkumar Gopalakrishnapillai

Nat Commun· July 2025

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Down syndrome and leukemia: An insight into the disease biology and current treatment options.
Sonali P Barwe, E Anders Kolb, Anilkumar Gopalakrishnapillai

Blood Rev· March 2024

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Tetraspanins set the stage for bone marrow microenvironment-induced chemoprotection in hematologic malignancies.
Anthony Quagliano, Anilkumar Gopalakrishnapillai, Sonali P Barwe

Blood Adv· August 2023

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Bone Marrow Microenvironment-Induced Chemoprotection in Rearranged Pediatric AML Is Overcome by Azacitidine-Panobinostat Combination.
Kara M Lehner, Anilkumar Gopalakrishnapillai, Edward Anders Kolb, Sonali P Barwe

Cancers (Basel)· June 2023

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Mesothelin: An Immunotherapeutic Target beyond Solid Tumors.
Joshua R Faust, Darcy Hamill, Edward Anders Kolb, Anilkumar Gopalakrishnapillai, Sonali P Barwe

Cancers (Basel)· March 2022

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Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts.
Sonali P Barwe, Fei Huang, Edward Anders Kolb, Anilkumar Gopalakrishnapillai

J Clin Med· March 2022

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The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML.
Emily B Heikamp, Jill A Henrich, Florian Perner, Eric M Wong, Charles Hatton, Anilkumar Gopalakrishnapillai

Blood· February 2022

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Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of and Mutations in Induced Pluripotent Stem Cells with Trisomy 21.
Sonali P Barwe, Aimy Sebastian, Ishnoor Sidhu, Edward Anders Kolb, Anilkumar Gopalakrishnapillai

Cells· February 2022

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Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia.
Sonali P Barwe, Anne Kisielewski, Ezio Bonvini, John Muth, Jan Davidson-Moncada, Anilkumar Gopalakrishnapillai

J Clin Med· February 2022

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Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies.
Anilkumar Gopalakrishnapillai, Colin E Correnti, Kristina Pilat, Ida Lin, Man Kid Chan

Cancers (Basel)· November 2021

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Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies.
Ishnoor Sidhu, Sonali P Barwe, Raju K Pillai, Anilkumar Gopalakrishnapillai

Cells· October 2021

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A 3-D hydrogel based system for hematopoietic differentiation and its use in modeling down syndrome associated transient myeloproliferative disorder.
Ishnoor Sidhu, Sonali P Barwe, Kristi L Kiick, E Anders Kolb, Anilkumar Gopalakrishnapillai

Biomater Sci· September 2021

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The extracellular matrix: A key player in the pathogenesis of hematologic malignancies.
Ishnoor Sidhu, Sonali P Barwe, Anilkumar Gopalakrishnapillai

Blood Rev· July 2021

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Mesothelin is a novel cell surface disease marker and potential therapeutic target in acute myeloid leukemia.
Allison J Kaeding, Sonali P Barwe, Anilkumar Gopalakrishnapillai, Rhonda E Ries, Todd A Alonzo

Blood Adv· May 2021

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Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology.
Sonali P Barwe, Ishnoor Sidhu, E Anders Kolb, Anilkumar Gopalakrishnapillai

Mol Ther Methods Clin Dev· December 2020

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CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia.
Anthony Quagliano, Anilkumar Gopalakrishnapillai, E Anders Kolb, Sonali P Barwe

Blood Adv· September 2020

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Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer.
Anthony Quagliano, Anilkumar Gopalakrishnapillai, Sonali P Barwe

Front Oncol· June 2020

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Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring.
Erin L Crowgey, Nitin Mahajan, Wing Hing Wong, Anilkumar Gopalakrishnapillai, Sonali P Barwe

BMC Med Genomics· March 2020

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Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia.
Anilkumar Gopalakrishnapillai, E Anders Kolb, Suzanne M McCahan, Sonali P Barwe

Leuk Res· July 2017

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Knockdown of sodium-calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells.
Sona Lakshme Balasubramaniam, Anilkumar Gopalakrishnapillai, Nicholas J Petrelli, Sonali P Barwe

J Biol Chem· July 2017

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CRISPR/Cas9-Directed Reassignment of the GATA1 Initiation Codon in K562 Cells to Recapitulate AML in Down Syndrome.
Kevin M Bloh, Pawel A Bialk, Anilkumar Gopalakrishnapillai, E Anders Kolb, Eric B Kmiec

Mol Ther Nucleic Acids· June 2017

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Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia.
Anthony Quagliano, Anilkumar Gopalakrishnapillai, Sonali P Barwe

Leuk Res· May 2017

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Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia.
Sonali P Barwe, Anthony Quagliano, Anilkumar Gopalakrishnapillai

Semin Oncol· April 2017

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Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice.
Anilkumar Gopalakrishnapillai, E Anders Kolb, Priyanka Dhanan, Aruna Sri Bojja, Robert W Mason

Front Oncol· July 2016

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