Publications by authors named "Ann T Doherty"

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Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action.
Katherine E Chapman, Eleanor C Wilde, Fiona M Chapman, Jatin R Verma, Ume-Kulsoom Shah, Ann T Doherty

Arch Toxicol· January 2021

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High information content assays for genetic toxicology testing: A report of the International Workshops on Genotoxicity Testing (IWGT).
Stephen D Dertinger, Yukari Totsuka, Jason H Bielas, Ann T Doherty, Jos Kleinjans

Mutat Res Genet Toxicol Environ Mutagen· November 2019

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A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells.
Eleanor C Wilde, Katherine E Chapman, Leanne M Stannard, Anna L Seager, Katja Brüsehafer, Ann T Doherty

Arch Toxicol· February 2018

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From the Cover: Does the Assessment of Nondisjunction Provide a More Sensitive Assay for the Detection of Aneugens?
Joanne M Elloway, Alexandra K Davies, Julie E Hayes, Ann T Doherty

Toxicol Sci· May 2017

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Viral Vectors: The Road to Reducing Genotoxicity.
Rhiannon M David, Ann T Doherty

Toxicol Sci· February 2017

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The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.
Katja Brüsehafer, Bella B Manshian, Ann T Doherty, Zoulikha M Zaïr, George E Johnson

Mutagenesis· March 2016

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Evaluation of 4,4'-diaminodiphenyl ether in the rat comet assay: Part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of in vivo rat alkaline comet assay.
Catherine C Priestley, Joanne S Walker, Michael R O'Donovan, Ann T Doherty

Mutat Res Genet Toxicol Environ Mutagen· July 2015

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Genotoxins induce binucleation in L5178Y and TK6 cells.
Ann T Doherty, Amy Wilson, Karolina Chocian, Jennifer Molloy, Margaret Clatworthy

Mutat Res Genet Toxicol Environ Mutagen· August 2014

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Chromosome breakage induced by the genotoxic agents mitomycin C and cytosine arabinoside is concentration and p53 dependent.
Katja Brüsehafer, Benjamin James Rees, Bella Barjouhi Manshian, Ann Teresa Doherty, Michael Richard O'Donovan

Toxicol Sci· July 2014

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Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells.
Anna L Seager, Ume-Kulsoom Shah, Katja Brüsehafer, John Wills, Bella Manshian, Ann T Doherty

Mutagenesis· May 2014

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Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. I: glucocorticoid receptor agonism.
Julie E Hayes, Ann T Doherty, Michelle Coulson, John R Foster, Peter T Cotton

Mutagenesis· March 2013

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Chromosome aberration frequency in rat peripheral lymphocytes increases with repeated dosing with hexamethylphosphoramide or cyclophosphamide.
Ann T Doherty, Julie Hayes, Paul Holme, Mike O'Donovan

Mutagenesis· September 2012

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The in vitro micronucleus assay.
Ann T Doherty

Methods Mol Biol· March 2012

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Cytogenetic in vivo assays in somatic cells.
Ann T Doherty, Adi Baumgartner, Diana Anderson

Methods Mol Biol· March 2012

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The ability of the mouse lymphoma TK assay to detect aneugens.
Michael D Fellows, Ann T Doherty, Catherine C Priestley, Victoria Howarth, Michael R O'Donovan

Mutagenesis· November 2011

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A rapid, semi-automated method for scoring micronuclei in mononucleated mouse lymphoma cells.
Ann T Doherty, Julie Hayes, Mick Fellows, Sarah Kirk, Mike O'Donovan

Mutat Res· November 2011

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Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate.
Catherine C Priestley, Richard M Green, Michael D Fellows, Ann T Doherty, Nikolas J Hodges

Toxicology· January 2010

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The rat bone marrow micronucleus test--study design and statistical power.
Julie Hayes, Ann T Doherty, Deborah J Adkins, Karen Oldman, Michael R O'Donovan

Mutagenesis· September 2009

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