Publications by authors named "Anna Horova"

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Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings.
Kamil Kuca, Jana Zdarova Karasova, Ondrej Soukup, Jiri Kassa, Eva Novotna, Anna Horova

Drug Des Devel Ther· September 2018

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7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.
Jan Korabecny, Martin Andrs, Eugenie Nepovimova, Rafael Dolezal, Katerina Babkova, Anna Horova

Molecules· December 2015

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Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.
Eugenie Nepovimova, Jan Korabecny, Rafael Dolezal, Katerina Babkova, Ales Ondrejicek, Anna Horova

J Med Chem· November 2015

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Preparation, in vitro screening and molecular modelling of monoquaternary compounds related to the selective acetylcholinesterase inhibitor BW284c51.
Ondrej Benek, Kamil Musilek, Anna Horova, Vlastimil Dohnal, Rafael Dolezal

Med Chem· September 2015

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A comparison of the reactivating and therapeutic efficacy of two newly developed oximes (k727 and k733) with oxime k203 and trimedoxime in tabun-poisoned rats and mice.
Jiri Kassa, Vendula Sepsova, Martina Tumova, Anna Horova, Kamil Musilek

Basic Clin Pharmacol Toxicol· April 2015

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A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.
Jiri Kassa, Vendula Sepsova, Lenka Matouskova, Anna Horova, Kamil Musilek

Toxicol Mech Methods· March 2015

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7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Jan Korabecny, Rafael Dolezal, Pavla Cabelova, Anna Horova, Eva Hruba

Eur J Med Chem· July 2014

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The evaluation of the reactivating and therapeutic efficacy of two novel oximes (K361 and K378) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.
Jiri Kassa, Vendula Sepsova, Martina Tumova, Kamil Musilek, Anna Horova

Toxicol Mech Methods· March 2014

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Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.
Marketa Komloova, Anna Horova, Martina Hrabinova, Daniel Jun, Martin Dolezal

Bioorg Med Chem Lett· December 2013

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The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.
Jiri Kassa, Vendula Sepsova, Kamil Musilek, Anna Horova

Toxicol Mech Methods· February 2013

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7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.
Katarina Spilovska, Jan Korabecny, Jan Kral, Anna Horova, Kamil Musilek

Molecules· February 2013

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Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties.
Jan Korabecny, Kamil Musilek, Filip Zemek, Anna Horova, Ondrej Holas

Bioorg Med Chem Lett· November 2011

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Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.
Marketa Komloova, Kamil Musilek, Anna Horova, Ondrej Holas, Vlastimil Dohnal

Bioorg Med Chem Lett· April 2011

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Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.
Kamil Musilek, Marketa Komloova, Ondrej Holas, Anna Horova, Miroslav Pohanka

Bioorg Med Chem· January 2011

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