Publications by authors named "Martin Andrs"

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Senataxin RNA/DNA helicase promotes replication restart at co-transcriptional R-loops to prevent MUS81-dependent fork degradation.
Satyajeet Rao, Martin Andrs, Kaustubh Shukla, Esin Isik, Christiane König

Nucleic Acids Res· September 2024

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MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops.
Esin Isik, Kaustubh Shukla, Michaela Pospisilova, Christiane König, Martin Andrs

Sci Adv· February 2024

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2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Vladimir Finger, Tomas Kucera, Radka Kafkova, Lubica Muckova, Rafael Dolezal, Martin Andrs

Eur J Med Chem· October 2023

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The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress.
Zhe Han, Martin Andrš, Bindhu K Madhavan, Serap Kaymak, Alba Sulaj

Nucleic Acids Res· March 2023

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Excessive reactive oxygen species induce transcription-dependent replication stress.
Martin Andrs, Henriette Stoy, Barbora Boleslavska, Nagaraja Chappidi, Radhakrishnan Kanagaraj

Nat Commun· March 2023

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DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells.
Barbora Boleslavska, Anna Oravetzova, Kaustubh Shukla, Zuzana Nascakova, Oluwakemi Ngozi Ibini, Martin Andrs

Nucleic Acids Res· November 2022

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7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
Lukas Gorecki, Darina Muthna, Sara Merdita, Martin Andrs, Tomas Kucera

Eur J Med Chem· October 2022

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Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer.
Lukas Gorecki, Martin Andrs, Jan Korabecny

Cancers (Basel)· February 2021

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Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy.
Lukas Gorecki, Martin Andrs, Martina Rezacova, Jan Korabecny

Pharmacol Ther· June 2020

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Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops.
Nagaraja Chappidi, Zuzana Nascakova, Barbora Boleslavska, Ralph Zellweger, Esin Isik, Martin Andrs

Mol Cell· February 2020

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RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription.
Martin Andrs, Zdenka Hasanova, Anna Oravetzova, Jana Dobrovolna, Pavel Janscak

Genes (Basel)· February 2020

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Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity.
Monika Pospisilova, Martin Andrs, Martina Seifrtova, Radim Havelek, Daniel Jun

Bioorg Chem· February 2019

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Purin-6-one and pyrrolo[2,3-d]pyrimidin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity.
Martin Andrs, Monika Pospisilova, Martina Seifrtova, Radim Havelek, Ales Tichy

Future Med Chem· September 2018

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Small Molecules Targeting Ataxia Telangiectasia and Rad3-Related (ATR) Kinase: An Emerging way to Enhance Existing Cancer Therapy.
Martin Andrs, Jan Korabecny, Eugenie Nepovimova, Daniel Jun, Zdenek Hodny

Curr Cancer Drug Targets· November 2016

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7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.
Jan Korabecny, Martin Andrs, Eugenie Nepovimova, Rafael Dolezal, Katerina Babkova

Molecules· December 2015

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Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.
Eugenie Nepovimova, Jan Korabecny, Rafael Dolezal, Katerina Babkova, Ales Ondrejicek, Martin Andrs

J Med Chem· November 2015

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From pyridinium-based to centrally active acetylcholinesterase reactivators.
Jan Korabecny, Ondrej Soukup, Rafael Dolezal, Katarina Spilovska, Eugenie Nepovimova, Martin Andrs

Mini Rev Med Chem· June 2015

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The development of ataxia telangiectasia mutated kinase inhibitors.
Martin Andrs, Jan Korabecny, Eugenie Nepovimova, Daniel Jun, Zdenek Hodny

Mini Rev Med Chem· June 2015

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Phosphatidylinositol 3-Kinase (PI3K) and phosphatidylinositol 3-kinase-related kinase (PIKK) inhibitors: importance of the morpholine ring.
Martin Andrs, Jan Korabecny, Daniel Jun, Zdenek Hodny, Jiri Bartek

J Med Chem· January 2015

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The development of ataxia telangiectasia mutated kinase inhibitors.
Martin Andrs, Jan Korabecny, Eugenie Nepovimova, Daniel Jun, Zdenek Hodny

Mini Rev Med Chem· October 2014

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7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Jan Korabecny, Rafael Dolezal, Pavla Cabelova, Anna Horova, Eva Hruba, Martin Andrs

Eur J Med Chem· July 2014

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