Publications by authors named "Radim Havelek"

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Anti-Endoglin monoclonal antibody prevents the progression of liver sinusoidal endothelial inflammation and fibrosis in MASH.
Samira Eissazadeh, Petra Fikrova, Jana Urbankova Rathouska, Ivana Nemeckova, Katarina Tripska, Radim Havelek

Life Sci· March 2025

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Undescribed Amaryllidaceae Alkaloids from and Their Cytotoxicity.
Jana Křoustková, Eliška Kohelová, Darina Muthná, Jiří Kuneš, Radim Havelek

J Nat Prod· September 2024

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Second-generation piperazine derivatives as promising radiation countermeasures.
Vojtěch Chmil, Natálie Živná, Marcela Milanová, Alžběta Filipová, Jaroslav Pejchal, Radim Havelek

RSC Med Chem· August 2024

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Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells.
Darja Koutova, Negar Maafi, Darina Muthna, Karel Kralovec, Jana Kroustkova, Radim Havelek

Biomed Pharmacother· October 2023

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Rh(III) and Ru(II) complexes with phosphanyl-alkylamines: inhibition of DNA synthesis induced by anticancer Rh complex.
Alena Mrkvicová, Eva Peterová, Ivan Nemec, Radka Křikavová, Darina Muthná, Radim Havelek

Future Med Chem· September 2023

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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their cytotoxic activities.
Aneta Ritomská, Darja Koutova, Jana Křoustková, Karel Královec, Darina Muthná, Radim Havelek

Saudi Pharm J· August 2023

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Author Correction: Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest.
Barbora Vítovcová, Veronika Skarková, Radim Havelek, Jiří Soukup, Ananya Pande

Sci Rep· June 2023

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Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest.
Barbora Vítovcová, Veronika Skarková, Radim Havelek, Jiří Soukup, Ananya Pande

Sci Rep· April 2023

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7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
Lukas Gorecki, Darina Muthna, Sara Merdita, Martin Andrs, Tomas Kucera, Radim Havelek

Eur J Med Chem· October 2022

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Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells.
Katarina Tripska, Ivone Cristina Igreja Sá, Martina Vasinova, Matej Vicen, Radim Havelek

Front Med (Lausanne)· September 2022

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Stability of a half-sandwich Os(II) complex with indomethacin-functionalized ligand in the presence of carboxypeptidase A.
Lukáš Masaryk, Darina Muthná, Petr Halaš, Pavel Zoufalý, Eva Peterová, Radim Havelek

Dalton Trans· June 2022

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The Effect of Chronic Exposure of Graphene Nanoplates on the Viability and Motility of A549 Cells.
Blanka Šestáková, Ladislava Schröterová, Aleš Bezrouk, Dana Čížková, Moustafa Elkalaf, Radim Havelek

Nanomaterials (Basel)· June 2022

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Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores.
Duong Thuy Bui, Radim Havelek, Karel Královec, Lenka Kubíčková, Jarmila Kuličková

Nanomaterials (Basel)· January 2022

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Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells.
Darja Koutová, Radim Havelek, Eva Peterová, Darina Muthná, Karel Královec

Int J Mol Sci· June 2021

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Disruption of Cell Adhesion and Cytoskeletal Networks by Thiol-Functionalized Silica-Coated Iron Oxide Nanoparticles.
Karel Královec, Lucie Melounková, Marcela Slováková, Nikola Mannová, Miloš Sedlák, Radim Havelek

Int J Mol Sci· December 2020

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Magnetic nanoparticles of Ga-substituted ε-Fe O for biomedical applications: Magnetic properties, transverse relaxivity, and effects of silica-coated particles on cytoskeletal networks.
Karel Královec, Radim Havelek, Darja Koutová, Pavel Veverka, Lenka Kubíčková

J Biomed Mater Res A· May 2020

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Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family.
Darja Koutová, Negar Maafi, Radim Havelek, Lubomír Opletal, Gerald Blunden

Molecules· May 2020

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A novel class of small molecule inhibitors with radioprotective properties.
Jan Marek, Ales Tichy, Radim Havelek, Martina Seifrtova, Alzbeta Filipova

Eur J Med Chem· February 2020

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Bersavine: A Novel Bisbenzylisoquinoline Alkaloidwith Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells.
Darja Koutova, Monika Kulhava, Radim Havelek, Martina Majorosova, Karel Královec

Molecules· February 2020

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Amaryllidaceae Alkaloids of Different Structural Types from L. cv. Professor Einstein and Their Cytotoxic Activity.
Kateřina Breiterová, Darja Koutová, Jana Maříková, Radim Havelek, Jiří Kuneš

Plants (Basel)· January 2020

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Substituted Piperazines as Novel Potential Radioprotective Agents.
Alzbeta Filipova, Jan Marek, Radim Havelek, Jaroslav Pejchal, Marcela Jelicova

Molecules· January 2020

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INVESTIGATION OF THE RADIOPROTECTIVE EFFECT OF ORTHOVANADATE IN MICE AFTER TOTAL BODY IRRADIATION.
Zuzana Šinkorová, Alžběta Filipová, Jiřina Vávrová, Jaroslav Pejchal, Lenka Andrejsová, Radim Havelek

Radiat Prot Dosimetry· December 2019

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Enhanced cytotoxicity of indenyl molybdenum(ii) compounds bearing a thiophene function.
Ondřej Mrózek, Lucie Melounková, Libor Dostál, Ivana Císařová, Aleš Eisner, Radim Havelek

Dalton Trans· August 2019

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Silica coated iron oxide nanoparticles-induced cytotoxicity, genotoxicity and its underlying mechanism in human HK-2 renal proximal tubule epithelial cells.
Karel Královec, Radim Havelek, Eliška Kročová, Lucie Kučírková, Martina Hauschke

Mutat Res Genet Toxicol Environ Mutagen· August 2019

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Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease.
Eliška Kohelová, Rozálie Peřinová, Negar Maafi, Jan Korábečný, Daniela Hulcová, Radim Havelek

Molecules· April 2019

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