Publications by authors named "Anna L Fallacara"

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The Pyrazolo[3,4-]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma.
Enrico Rango, Fabio Pastorino, Chiara Brignole, Arianna Mancini, Federica Poggialini, Anna Lucia Fallacara

Biomedicines· March 2022

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Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
Enrico Rango, Lucia D'Antona, Giulia Iovenitti, Annalaura Brai, Arianna Mancini, Anna Lucia Fallacara

Eur J Med Chem· November 2021

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Predictive Gene Signature for Pyrazolopyrimidine Derivative c-Src Inhibitor 10a Sensitivity in Melanoma Cells.
Baris Kucukkaraduman, Can Turk, Anna L Fallacara, Murat Isbilen, Kerem M Senses

ACS Med Chem Lett· May 2020

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Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines.
Anna Lucia Fallacara, Raffaele Passannanti, Mattia Mori, Giulia Iovenitti, Francesca Musumeci

Eur J Med Chem· November 2019

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Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line.
Francesco P Cammarata, Filippo Torrisi, Giusi I Forte, Luigi Minafra, Valentina Bravatà, Anna L Fallacara

Int J Mol Sci· September 2019

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An Update on JAK Inhibitors.
Francesca Musumeci, Chiara Greco, Ilaria Giacchello, Anna Lucia Fallacara, Munjed M Ibrahim

Curr Med Chem· July 2019

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A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-]Pyrimidine Dual Src/P-Glycoprotein Inhibitor.
Anna Lucia Fallacara, Claudio Zamperini, Ana Podolski-Renić, Jelena Dinić, Tijana Stanković

Cancers (Basel)· June 2019

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One-pot synthesis of spiro(indoline-3,4'-pyrazolo[3,4-b]pyridine)-5'-carbonitriles as p53-MDM2 interaction inhibitors.
Hany S Ibrahim, Wagdy M Eldehna, Anna Lucia Fallacara, Esam R Ahmed, Hazem A Ghabbour

Future Med Chem· December 2018

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Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.
Alessio Molinari, Anna Lucia Fallacara, Salvatore Di Maria, Claudio Zamperini, Federica Poggialini

Bioorg Med Chem Lett· November 2018

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Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction.
Ilaria D'Agostino, Ilaria Giacchello, Giulio Nannetti, Anna Lucia Fallacara, Davide Deodato

Eur J Med Chem· September 2018

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Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors.
Cinzia Maria Francini, Francesca Musumeci, Anna Lucia Fallacara, Lorenzo Botta, Alessio Molinari

Molecules· September 2018

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.
Francesca Musumeci, Monica Sanna, Chiara Greco, Ilaria Giacchello, Anna Lucia Fallacara

Expert Opin Ther Pat· December 2017

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Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors.
Francesca Musumeci, Monica Sanna, Giancarlo Grossi, Chiara Brullo, Anna Lucia Fallacara

Curr Med Chem· September 2017

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Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.
Anna Lucia Fallacara, Arianna Mancini, Claudio Zamperini, Elena Dreassi, Stefano Marianelli

Bioorg Med Chem Lett· July 2017

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Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.
Giulia Vignaroli, Giulia Iovenitti, Claudio Zamperini, Federica Coniglio, Pierpaolo Calandro, Anna Lucia Fallacara

J Med Chem· July 2017

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Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma.
Francesca Musumeci, Anna Lucia Fallacara, Chiara Brullo, Giancarlo Grossi, Lorenzo Botta

Eur J Med Chem· February 2017

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Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma.
Kerem M Senses, Mehdi Ghasemi, Muhammad W Akbar, Murat Isbilen, Anna L Fallacara

Medchemcomm· January 2017

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3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity.
Loana Musso, Raffaella Cincinelli, Valentina Zuco, Michelandrea De Cesare, Franco Zunino, Anna Lucia Fallacara

ChemMedChem· August 2016

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A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant.
Marco Radi, Ralf Schneider, Anna Lucia Fallacara, Lorenzo Botta, Emmanuele Crespan

Bioorg Med Chem Lett· August 2016

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4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
Iuni M L Trist, Giulio Nannetti, Cristina Tintori, Anna Lucia Fallacara, Davide Deodato

J Med Chem· March 2016

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Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors.
Cinzia Maria Francini, Anna Lucia Fallacara, Roberto Artusi, Laura Mennuni, Alessia Calgani

ChemMedChem· December 2015

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Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors.
Cristina Tintori, Giuseppina La Sala, Giulia Vignaroli, Lorenzo Botta, Anna Lucia Fallacara

J Med Chem· June 2015

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Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.
Cristina Tintori, Anna Lucia Fallacara, Marco Radi, Claudio Zamperini, Elena Dreassi

J Med Chem· January 2015

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Protein-protein interactions and human cellular cofactors as new targets for HIV therapy.
Cristina Tintori, Annalaura Brai, Anna Lucia Fallacara, Roberta Fazi, Silvia Schenone

Curr Opin Pharmacol· October 2014

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Insight into the allosteric inhibition of Abl kinase.
Anna Lucia Fallacara, Cristina Tintori, Marco Radi, Silvia Schenone, Maurizio Botta

J Chem Inf Model· May 2014

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