Publications by authors named "Laura Mennuni"

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Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors.
Cinzia Maria Francini, Francesca Musumeci, Anna Lucia Fallacara, Lorenzo Botta, Alessio Molinari, Laura Mennuni

Molecules· September 2018

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Development of subnanomolar-affinity serotonin 5-HT receptor ligands based on quinoline structures.
Federica Castriconi, Marco Paolino, Giorgio Grisci, Cinzia Maria Francini, Annalisa Reale, Laura Mennuni

Medchemcomm· September 2018

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Pharmacological characterisation of CR6086, a potent prostaglandin E receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.
Gianfranco Caselli, Albino Bonazzi, Marco Lanza, Flora Ferrari, Daniele Maggioni, Laura Mennuni

Arthritis Res Ther· March 2018

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Multivalent ligands for the serotonin 5-HT receptor.
Federica Castriconi, Marco Paolino, Alessandro Donati, Germano Giuliani, Maurizio Anzini, Laura Mennuni

Medchemcomm· March 2017

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Phenylindenone isomers as divergent modulators of p38α MAP kinase.
Andrea Cappelli, Chiara Nannicini, Alessia Chelini, Marco Paolino, Germano Giuliani, Laura Mennuni

Bioorg Med Chem Lett· November 2016

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Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors.
Cinzia Maria Francini, Anna Lucia Fallacara, Roberto Artusi, Laura Mennuni, Alessia Calgani

ChemMedChem· December 2015

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Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation.
Giovanni Caprioli, Valerio Mammoli, Massimo Ricciutelli, Gianni Sagratini, Massimo Ubaldi, Laura Mennuni

Eur J Pharmacol· December 2015

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Supramolecular glycodendrimer-based hybrid drugs.
Marco Paolino, Hartmut Komber, Laura Mennuni, Gianfranco Caselli, Dietmar Appelhans

Biomacromolecules· November 2014

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Dendrimeric tetravalent ligands for the serotonin-gated ion channel.
Marco Paolino, Laura Mennuni, Germano Giuliani, Maurizio Anzini, Marco Lanza

Chem Commun (Camb)· August 2014

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Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold.
Federica Castriconi, Marco Paolino, Germano Giuliani, Maurizio Anzini, Giuseppe Campiani, Laura Mennuni

Eur J Med Chem· July 2014

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Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Andrea Cappelli, Monica Manini, Salvatore Valenti, Federica Castriconi, Germano Giuliani, Laura Mennuni

Eur J Med Chem· May 2013

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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP4 receptor.
Luigi Piero Stasi, Kanji Bhimani, Manuela Borriello, Luca Canciani, Gianfranco Caselli, Laura Mennuni

Bioorg Med Chem Lett· November 2011

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New anthranilic acid based antagonists with high affinity and selectivity for the human cholecystokinin receptor 1 (hCCK1-R).
Michela V Pavan, Lucia Lassiani, Federico Berti, Giorgio Stefancich, Alessia Ciogli, Laura Mennuni

J Med Chem· August 2011

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Bivalent Ligands for the Serotonin 5-HT3 Receptor.
Andrea Cappelli, Monica Manini, Marco Paolino, Andrea Gallelli, Maurizio Anzini, Laura Mennuni

ACS Med Chem Lett· August 2011

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Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain.
Flora Ferrari, Simonetta Fiorentino, Laura Mennuni, Paolo Garofalo, Ornella Letari

J Pain Res· July 2011

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The interactions of the 5-HT3 receptor with quipazine-like arylpiperazine ligands: the journey track at the end of the first decade of the third millennium.
Andrea Cappelli, Stefania Butini, Antonella Brizzi, Sandra Gemma, Salvatore Valenti, Laura Mennuni

Curr Top Med Chem· September 2010

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Design, synthesis, and preliminary biological evaluation of pyrrolo[3,4-c]quinolin-1-one and oxoisoindoline derivatives as aggrecanase inhibitors.
Andrea Cappelli, Chiara Nannicini, Salvatore Valenti, Germano Giuliani, Maurizio Anzini, Laura Mennuni

ChemMedChem· May 2010

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Multivalent supramolecular dendrimer-based drugs.
Simone Galeazzi, Thomas M Hermans, Marco Paolino, Maurizio Anzini, Laura Mennuni

Biomacromolecules· January 2010

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Anthranilic acid based CCK1 receptor antagonists: blocking the receptor with the same 'words' of the endogenous ligand.
Lucia Lassiani, Michela V Pavan, Federico Berti, George Kokotos, Theodoros Markidis, Laura Mennuni

Bioorg Med Chem· March 2009

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Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.
Andrea Cappelli, Chiara Nannicini, Andrea Gallelli, Germano Giuliani, Salvatore Valenti, Laura Mennuni

J Med Chem· April 2008

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Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.
Andrea Cappelli, Gal la Pericot Mohr, Germano Giuliani, Simone Galeazzi, Maurizio Anzini, Laura Mennuni

J Med Chem· November 2006

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Anthranilic acid based CCK1 receptor antagonists: preliminary investigation on their second "touch point".
Antonio Varnavas, Lucia Lassiani, Valentina Valenta, Laura Mennuni, Francesco Makovec

Eur J Med Chem· June 2005

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Structure-affinity relationship studies on arylpiperazine derivatives related to quipazine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor.
Andrea Cappelli, Germano Giuliani, Andrea Gallelli, Salvatore Valenti, Maurizio Anzini, Laura Mennuni

Bioorg Med Chem· May 2005

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Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.
Andrea Cappelli, Andrea Gallelli, Monica Manini, Maurizio Anzini, Laura Mennuni

J Med Chem· May 2005

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Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.
Flora Ferrari, Laura Mennuni, Gianfranco Caselli, Tiziano Zanelli, Francesco Makovec

Eur J Pharmacol· November 2004

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