Publications by authors named "Ornella Letari"

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CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma.
Chiara Galimberti, Tiziana Piepoli, Ornella Letari, Roberto Artusi, Stefano Persiani

Am J Cancer Res· July 2021

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CR4056, a powerful analgesic imidazoline-2 receptor ligand, inhibits the inflammation-induced PKCε phosphorylation and membrane translocation in sensory neurons.
Vittorio Vellani, Chiara Sabatini, Chiara Milia, Gianfranco Caselli, Marco Lanza, Ornella Letari

Br J Pharmacol· January 2020

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Pharmacological characterisation of CR6086, a potent prostaglandin E receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.
Gianfranco Caselli, Albino Bonazzi, Marco Lanza, Flora Ferrari, Daniele Maggioni, Ornella Letari

Arthritis Res Ther· March 2018

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Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Andrea Cappelli, Monica Manini, Salvatore Valenti, Federica Castriconi, Germano Giuliani, Ornella Letari

Eur J Med Chem· May 2013

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Discovery, synthesis, selectivity modulation and DMPK characterization of 5-azaspiro[2.4]heptanes as potent orexin receptor antagonists.
Luigi Piero Stasi, Roberto Artusi, Clara Bovino, Benedetta Buzzi, Luca Canciani, Ornella Letari

Bioorg Med Chem Lett· May 2013

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CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats.
Cristina Meregalli, Cecilia Ceresa, Annalisa Canta, Valentina Alda Carozzi, Alessia Chiorazzi, Ornella Letari

J Pain Res· October 2012

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Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain.
Flora Ferrari, Simonetta Fiorentino, Laura Mennuni, Paolo Garofalo, Ornella Letari

J Pain Res· July 2011

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Efficacy of CR3294, a new benzamidine derivative, in the prevention of 5-fluorouracil-induced gastrointestinal mucositis and diarrhea in mice.
Ornella Letari, Catherine Booth, Albino Bonazzi, Paolo Garofalo, Francesco Makovec

Cancer Chemother Pharmacol· October 2010

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Induction of autophagic cell death by a novel molecule is increased by hypoxia.
Marco Tafani, Luana Schito, Tahira Anwar, Manuela Indelicato, Patrizio Sale, Ornella Letari

Autophagy· November 2008

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