Publications by authors named "Anna Offersgaard"

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SARS-CoV-2 Mpro inhibitor ensitrelvir: asymmetrical cross-resistance with nirmatrelvir and emerging resistance hotspots.
Yuyong Zhou, Karen A Gammeltoft, Helena D Tjørnelund-Sjursen, Line A Ryberg, Anna Offersgaard

Emerg Microbes Infect· December 2025

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Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein.
Laura Radić, Anna Offersgaard, Tereza Kadavá, Ian Zon, Joan Capella-Pujol

Proc Natl Acad Sci U S A· April 2025

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Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection.
Katharina Wørzner, Signe Tandrup Schmidt, Julie Zimmermann, Ahmad Tami, Charlotta Polacek, Anna Offersgaard

EBioMedicine· March 2025

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An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals.
Anna Offersgaard, Carlos R Duarte Hernandez, Yuyong Zhou, Zhe Duan, Karen Anbro Gammeltoft

Sci Rep· July 2024

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Substitutions in SARS-CoV-2 Mpro Selected by Protease Inhibitor Boceprevir Confer Resistance to Nirmatrelvir.
Karen Anbro Gammeltoft, Yuyong Zhou, Line Abildgaard Ryberg, Long V Pham, Alekxander Binderup, Anna Offersgaard

Viruses· September 2023

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Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
Anna V Sherwood, Lizandro R Rivera-Rangel, Line A Ryberg, Helena S Larsen, Klara M Anker, Anna Offersgaard

Nature· July 2023

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Toward a vaccine against hepatitis C virus.
Anna Offersgaard, Jens Bukh, Judith M Gottwein

Science· April 2023

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Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice.
Garazi Pena Alzua, Anne Finne Pihl, Anna Offersgaard, Carlos Rene Duarte Hernandez, Zhe Duan

Gut· March 2023

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Identification of novel neutralizing determinants for protection against HCV.
Garazi P Alzua, Anne F Pihl, Anna Offersgaard, Rodrigo Velázquez-Moctezuma, Carlos R Duarte Hernandez

Hepatology· March 2023

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An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals.
Anna Offersgaard, Carlos Rene Duarte Hernandez, Shan Feng, Pavel Marichal-Gallardo, Kenn Holmbeck

iScience· February 2023

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Effect of Glycan Shift on Antibodies against Hepatitis C Virus E2 412-425 Epitope Elicited by Chimeric sHBsAg-Based Virus-Like Particles.
Anna Czarnota, Anna Offersgaard, Ania Owsianka, Garazi Peña Alzua, Jens Bukh

Microbiol Spectr· January 2023

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Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system.
Yuyong Zhou, Karen Anbro Gammeltoft, Line Abildgaard Ryberg, Long V Pham, Helena Damtoft Tjørnelund, Anna Offersgaard

Sci Adv· December 2022

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Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice.
Anne Finne Pihl, Shan Feng, Anna Offersgaard, Garazi Peña Alzua, Elias Honerød Augestad

J Hepatol· May 2022

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High-Titer Hepatitis C Virus Production in a Scalable Single-Use High Cell Density Bioreactor.
Anna Offersgaard, Carlos Rene Duarte Hernandez, Anne Finne Pihl, Nandini Prabhakar Venkatesan, Henrik Krarup

Vaccines (Basel)· February 2022

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Efficacy of Ion-Channel Inhibitors Amantadine, Memantine and Rimantadine for the Treatment of SARS-CoV-2 In Vitro.
Yuyong Zhou, Karen A Gammeltoft, Andrea Galli, Anna Offersgaard, Ulrik Fahnøe

Viruses· October 2021

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Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 .
Karen A Gammeltoft, Yuyong Zhou, Carlos R Duarte Hernandez, Andrea Galli, Anna Offersgaard

Antimicrob Agents Chemother· August 2021

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In vitro efficacy of artemisinin-based treatments against SARS-CoV-2.
Yuyong Zhou, Kerry Gilmore, Santseharay Ramirez, Eva Settels, Karen A Gammeltoft, Anna Offersgaard

Sci Rep· July 2021

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SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor.
Anna Offersgaard, Carlos Rene Duarte Hernandez, Anne Finne Pihl, Rui Costa, Nandini Prabhakar Venkatesan

Vaccines (Basel)· June 2021

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Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine.
Keven Lothert, Anna F Offersgaard, Anne F Pihl, Christian K Mathiesen, Tanja B Jensen

Sci Rep· October 2020

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Specific Antibodies Induced by Immunization with Hepatitis B Virus-Like Particles Carrying Hepatitis C Virus Envelope Glycoprotein 2 Epitopes Show Differential Neutralization Efficiency.
Anna Czarnota, Anna Offersgaard, Anne Finne Pihl, Jannick Prentoe, Jens Bukh

Vaccines (Basel)· June 2020

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High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals.
Anne F Pihl, Anna F Offersgaard, Christian K Mathiesen, Jannick Prentoe, Ulrik Fahnøe

Sci Rep· November 2018

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