Publications by authors named "Anna Sava"

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Brain-penetrant cyanoindane and cyanotetralin inhibitors of G2019S-LRRK2 kinase activity.
Albert W Garofalo, Jacob Schwarz, Kerry Zobel, Claudia Beato, Silvia Bernardi, Anna Sava

Bioorg Med Chem Lett· October 2023

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Selective Inhibitors of G2019S-LRRK2 Kinase Activity.
Albert W Garofalo, Jessica Bright, Stéphane De Lombaert, Alyssa M A Toda, Kerry Zobel, Anna Sava

J Med Chem· December 2020

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Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors.
Elisabetta Perdona, Palmina Cavallini, Anna Sava, Cristiana Griffante, Daniel J Ricca

Neurosci Lett· October 2019

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Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors.
Nadia M J Rupniak, Elisabetta Perdona, Cristiana Griffante, Palmina Cavallini, Anna Sava

PLoS One· April 2019

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1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists.
Fabrizio Micheli, Alessia Bacchi, Simone Braggio, Laura Castelletti, Palmina Cavallini, Anna Sava

J Med Chem· September 2016

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Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists.
Fabrizio Micheli, Susanna Cremonesi, Teresa Semeraro, Luca Tarsi, Silvia Tomelleri, Anna Sava

Bioorg Med Chem Lett· February 2016

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The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours.
Eamonn Kelly, Stuart J Mundell, Anna Sava, Adelheid L Roth, Antonio Felici

Psychopharmacology (Berl)· January 2015

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NMDA-induced ERK signalling is mediated by NR2B subunit in rat cortical neurons and switches from positive to negative depending on stage of development.
Anna Sava, Elena Formaggio, Corrado Carignani, Filippo Andreetta, Ezio Bettini

Neuropharmacology· February 2012

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Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors.
Ezio Bettini, Anna Sava, Cristiana Griffante, Corrado Carignani, Alberto Buson

J Pharmacol Exp Ther· December 2010

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Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders.
Massimo Gianotti, Maurizio Botta, Stephen Brough, Renzo Carletti, Emiliano Castiglioni, Anna Sava

J Med Chem· November 2010

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Design and synthesis of novel tricyclic benzoxazines as potent 5-HT(1A/B/D) receptor antagonists leading to the discovery of 6-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide (GSK588045).
Steven M Bromidge, Roberto Arban, Barbara Bertani, Silvia Bison, Manuela Borriello, Anna Sava

J Med Chem· August 2010

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The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.
Pier L D'Alessandro, Corrado Corti, Adelheid Roth, Annarosa Ugolini, Anna Sava

Bioorg Med Chem Lett· January 2010

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