Publications by authors named "Anne B Eldrup"

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Sclerotic GVHD and Scleroderma Share Dysregulated Gene Expression that is Ameliorated by EREG Therapeutic Antibody.
Nathan M Newton, Kriti Agrawal, Anahi V Odell, Timothy Scott Tracy, Craig Stanway Hackett, Anne B Eldrup

Blood· September 2025

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Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists.
Steven J Taylor, Fariba Soleymanzadeh, Ingo Muegge, Isamu Akiba, Naoyuki Taki, Anne B Eldrup

Bioorg Med Chem Lett· April 2013

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Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat.
John D Huber, Jörg Bentzien, Stephen J Boyer, Jennifer Burke, Stéphane De Lombaert, Anne B Eldrup

J Med Chem· August 2012

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Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method.
Jennifer A Kowalski, Alan D Swinamer, Ingo Muegge, Anne B Eldrup, Alison Kukulka

Bioorg Med Chem Lett· June 2010

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Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase.
Anne B Eldrup, Fariba Soleymanzadeh, Neil A Farrow, Alison Kukulka, Stéphane De Lombaert

Bioorg Med Chem Lett· January 2010

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Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.
Anne B Eldrup, Fariba Soleymanzadeh, Steven J Taylor, Ingo Muegge, Neil A Farrow

J Med Chem· October 2009

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Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase.
Steven J Taylor, Fariba Soleymanzadeh, Anne B Eldrup, Neil A Farrow, Ingo Muegge

Bioorg Med Chem Lett· October 2009

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Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.
Klaus Albertshofer, Andrew M Siwkowski, Edward V Wancewicz, Christine C Esau, Tanya Watanabe, Anne B Eldrup

J Med Chem· October 2005

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Inhibitory effect of 2'-substituted nucleosides on hepatitis C virus replication correlates with metabolic properties in replicon cells.
Joanne E Tomassini, Krista Getty, Mark W Stahlhut, Sung Shim, Balkrishen Bhat, Anne B Eldrup

Antimicrob Agents Chemother· May 2005

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Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.
Thazha P Prakash, Marija Prhavc, Anne B Eldrup, P Dan Cook, Steven S Carroll

J Med Chem· February 2005

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Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs.
Sanjib Bera, Leila Malik, Balkrishen Bhat, Steven S Carroll, Renee Hrin, Anne B Eldrup

Bioorg Med Chem· December 2004

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A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties.
David B Olsen, Anne B Eldrup, Linda Bartholomew, Balkrishen Bhat, Michele R Bosserman

Antimicrob Agents Chemother· October 2004

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Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication.
Anne B Eldrup, Marija Prhavc, Jennifer Brooks, Balkrishen Bhat, Thazha P Prakash

J Med Chem· October 2004

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Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing.
Andrew M Siwkowski, Leila Malik, Christine C Esau, Martin A Maier, Edward V Wancewicz, Anne B Eldrup

Nucleic Acids Res· June 2004

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Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase.
Anne B Eldrup, Charles R Allerson, C Frank Bennett, Sanjib Bera, Balkrishen Bhat

J Med Chem· April 2004

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro.
Giovanni Migliaccio, Joanne E Tomassini, Steven S Carroll, Licia Tomei, Sergio Altamura, Anne B Eldrup

J Biol Chem· December 2003

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Synthesis and evaluation of optically pure dioxolanes as inhibitors of hepatitis C virus RNA replication.
Sanjib Bera, Leila Malik, Balkrishen Bhat, Steven S Carroll, Malcolm MacCoss, Anne B Eldrup

Bioorg Med Chem Lett· December 2003

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Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.
Steven S Carroll, Joanne E Tomassini, Michele Bosserman, Krista Getty, Mark W Stahlhut, Anne B Eldrup

J Biol Chem· April 2003

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1,8-Naphthyridin-2,7-(1,8H)-dione is an effective mimic of protonated cytosine in peptide nucleic acid triplex recognition systems.
Caspar Christensen, Anne B Eldrup, Gerald Haaima, Peter E Nielsen

Bioorg Med Chem Lett· November 2002

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Substituted 1,8-naphthyridin-2(1H)-ones are superior to thymine in the recognition of adenine in duplex as well as triplex structures.
Anne B Eldrup, Caspar Christensen, Gerald Haaima, Peter E Nielsen

J Am Chem Soc· April 2002

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