Publications by authors named "David B Olsen"

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MK-7602: a potent multi-stage dual-targeting antimalarial.
Paola Favuzza, Josephine Palandri, Manuel de Lera Ruiz, Wendy Bailey, Christopher W Boyce, David B Olsen

EBioMedicine· December 2025

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Structure-activity analysis of imino-pyrimidinone-fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors.
Anthony N Hodder, Brad E Sleebs, Greg Adams, Sina Rezazadeh, Anna Ngo, David B Olsen

FEBS J· June 2025

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Association Between β-Adrenoreceptor Agonists and Antagonists and Parkinson's Disease: Systematic Review and Meta-Analysis.
Agnieszka Szmigiel, Miguel Monteiro da Rocha, Kate Browne, Daniel Morales, David Benee Olsen

Pharmacoepidemiol Drug Saf· April 2025

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COVID-19 Vaccines and Heavy Menstrual Bleeding: The Impact of Media Attention on Reporting to EudraVigilance.
María Gordillo-Marañón, Agnieszka Szmigiel, Vladimíra Yalmanová, Irina Caplanusi, Georgy Genov, David Benee Olsen

Drug Saf· August 2024

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Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling.
Nadine Alvarez, Gregory C Adam, John A Howe, Vijeta Sharma, Matthew D Zimmerman, David B Olsen

Viruses· July 2024

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Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities.
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, Veena D Yadav, Brendan M Crowley, David B Olsen

ACS Infect Dis· May 2024

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Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease.
Rajini R Mudhasani, Joseph W Golden, Gregory C Adam, Timothy J Hartingh, Krishna P Kota, David B Olsen

Microbiol Spectr· April 2024

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Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Valerie W Shurtleff, Mark E Layton, Craig A Parish, James J Perkins, John D Schreier, David B Olsen

J Med Chem· March 2024

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Pharmacological validation of dihydrofolate reductase as a drug target in .
Wassihun Wedajo Aragaw, Dereje A Negatu, Christopher J Bungard, Véronique A Dartois, Abdellatif El Marrouni, David B Olsen

Antimicrob Agents Chemother· January 2024

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Structure activity relationship of N-1 substituted 1,5-naphthyrid-2-one analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-9).
Sheo B Singh, Christopher M Tan, David Kaelin, Peter T Meinke, Lynn Miesel, David B Olsen

Bioorg Med Chem Lett· November 2022

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The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria.
Manuel de Lera Ruiz, Paola Favuzza, Zhuyan Guo, Lianyun Zhao, Bin Hu, David B Olsen

ACS Med Chem Lett· November 2022

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Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
Abdeldjalil Madani, Dereje A Negatu, Abdellatif El Marrouni, Randy R Miller, Christopher W Boyce, David B Olsen

Antimicrob Agents Chemother· September 2022

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DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in .
Melissa D Chengalroyen, Mandy K Mason, Alessandro Borsellini, Raffaella Tassoni, Garth L Abrahams, David B Olsen

ACS Infect Dis· March 2022

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Identification of β-Lactams Active against by a Consortium of Pharmaceutical Companies and Academic Institutions.
Ben Gold, Jun Zhang, Landys Lopez Quezada, Julia Roberts, Yan Ling, David B Olsen

ACS Infect Dis· March 2022

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The Tuberculosis Drug Accelerator at year 10: what have we learned?
Bree B Aldridge, David Barros-Aguirre, Clifton E Barry, Robert H Bates, Steven J Berthel, David B Olsen

Nat Med· August 2021

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Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing.
Xi He, Shuo Quan, Min Xu, Silveria Rodriguez, Shih Lin Goh, David B Olsen

Proc Natl Acad Sci U S A· April 2021

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SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.
Nicholas Murgolo, Alex G Therien, Bonnie Howell, Daniel Klein, Kenneth Koeplinger, David B Olsen

PLoS Pathog· February 2021

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.
Paola Favuzza, Manuel de Lera Ruiz, Jennifer K Thompson, Tony Triglia, Anna Ngo, David B Olsen

Cell Host Microbe· April 2020

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Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis.
Trygve Holmøy, Børre Fevang, David Benee Olsen, Olav Spigset, Lars Bø

BMC Res Notes· August 2019

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Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
Roberto A Crespo, Qun Dang, Nian E Zhou, Liam M Guthrie, Thomas C Snavely, David B Olsen

J Med Chem· May 2019

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[Valproate is contraindicated in pregnancy].
David Benee Olsen, Arton Baftiu

Tidsskr Nor Laegeforen· February 2019

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Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
Sangmi Oh, Yumi Park, Curtis A Engelhart, Joshua B Wallach, Dirk Schnappinger, David B Olsen

J Med Chem· November 2018

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Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis.
Sheo B Singh, Joshua Odingo, Mai A Bailey, Bjorn Sunde, Aaron Korkegian, David B Olsen

BMC Res Notes· June 2018

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Development of a New Structural Class of Broadly Acting HCV Non-Nucleoside Inhibitors Leading to the Discovery of MK-8876.
Casey C McComas, Anandan Palani, Wei Chang, M Katharine Holloway, Charles A Lesburg, David B Olsen

ChemMedChem· September 2017

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Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.
John P Santa Maria, Yumi Park, Lihu Yang, Nicholas Murgolo, Michael D Altman, David B Olsen

ACS Chem Biol· September 2017

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