Publications by authors named "Bree B Aldridge"

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GEODE: an tool that translates to predictions of tuberculosis antibiotic combination efficacy.
Maral Budak, Mariana Pereira Moraes, Talia Greenstein, Pauline Maiello, H Jacob Borish, Bree B Aldridge

Front Pharmacol· November 2025

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Strain diversity drives heterogeneous responses to tuberculosis combination therapy.
Michelle H Yoon, Peter H Culviner, Mariana Pereira Moraes, Hidetomi Nitta, Nguyen Thuy Thuong Thuong, Bree B Aldridge

bioRxiv· October 2025

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Targeting de novo purine biosynthesis for tuberculosis treatment.
Dirk A Lamprecht, Richard J Wall, Annelies Leemans, Barry Truebody, Joke Sprangers, Bree B Aldridge

Nature· August 2025

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Erratum for Peroutka-Bigus et al., "Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease".
Nathan Peroutka-Bigus, Elizabeth J Brooks, Michelle E Ramey, Hope D'Erasmo, Jackie P Ernest, Bree B Aldridge

Antimicrob Agents Chemother· August 2025

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Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action.
William C Johnson, Ares Alivisatos, Trever C Smith, Nhi Van, Vijay Soni, Bree B Aldridge

Cell Syst· August 2025

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Increased proportion of growth-arrested bacilli in acidic pH adaptation promotes treatment survival.
Eun Seon Chung, William C Johnson, Maliwan Kamkaew, Morgan E McNellis, Trever C Smith, Bree B Aldridge

bioRxiv· July 2025

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Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease.
Nathan Peroutka-Bigus, Elizabeth J Brooks, Michelle E Ramey, Hope D'Erasmo, Jackie P Ernest, Bree B Aldridge

Antimicrob Agents Chemother· May 2025

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Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy.
John W Ribis, César Nieto, Nicholas V DiBenedetto, Anchal Mehra, Pola Kuhn, Bree B Aldridge

PLoS Pathog· May 2025

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Unique growth and morphology properties of Clade 5 strains revealed by single-cell time-lapse microscopy.
John W Ribis, César Nieto, Nicholas V DiBenedetto, Anchal Mehra, Pola Kuhn, Bree B Aldridge

bioRxiv· May 2025

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Large-scale combination screens reveal small-molecule sensitization of antibiotic-resistant gram-negative ESKAPE pathogens.
Megan W Tse, Meilin Zhu, Benjamin Peters, Efrat Hamami, Julie Chen, Bree B Aldridge

Proc Natl Acad Sci U S A· April 2025

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Predicting tuberculosis drug efficacy in preclinical and clinical models from data.
Janice J N Goh, Anu Patel, Bernard Ngara, Rob C van Wijk, Natasha Strydom, Bree B Aldridge

iScience· March 2025

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Multiomic analysis identifies suppressive myeloid cell populations in human TB granulomas.
Neharika Jain, Emmanuel C Ogbonna, Zoltan Maliga, Connor Jacobson, Liang Zhang, Bree B Aldridge

bioRxiv· March 2025

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Single-cell imaging of the Mycobacterium tuberculosis cell cycle reveals linear and heterogenous growth.
Eun Seon Chung, Prathitha Kar, Maliwan Kamkaew, Ariel Amir, Bree B Aldridge

Nat Microbiol· December 2024

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identification of underutilized β-lactam combinations against methicillin-resistant bacteremia isolates.
Kathleen P Davis, Laura A McDermott, David R Snydman, Bree B Aldridge

Microbiol Spectr· August 2024

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Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model responses.
Kathleen P Davis, Yoelkys Morales, Rachel J Ende, Ryan Peters, Anne L McCabe, Bree B Aldridge

mBio· March 2024

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Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens.
Megan W Tse, Meilin Zhu, Benjamin Peters, Efrat Hamami, Julie Chen, Bree B Aldridge

bioRxiv· March 2024

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Semi-automated colony-forming unit counting for biosafety level 3 laboratories.
Soorya Janakiraman, Sophie Engels, Pariksheet Nanda, Maral Budak, Talia Greenstein, Bree B Aldridge

STAR Protoc· September 2023

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Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus.
Nhi Van, Yonatan N Degefu, Pathricia A Leus, Jonah Larkins-Ford, Jacob Klickstein, Bree B Aldridge

Antimicrob Agents Chemother· July 2023

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grows linearly at the single-cell level with larger variability than model organisms.
Eun Seon Chung, Prathitha Kar, Maliwan Kamkaew, Ariel Amir, Bree B Aldridge

bioRxiv· May 2023

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Tools to develop antibiotic combinations that target drug tolerance in .
Talia Greenstein, Bree B Aldridge

Front Cell Infect Microbiol· February 2023

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Advances in the design of combination therapies for the treatment of tuberculosis.
Jonah Larkins-Ford, Bree B Aldridge

Expert Opin Drug Discov· January 2023

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Tuberculosis treatment failure associated with evolution of antibiotic resilience.
Qingyun Liu, Junhao Zhu, Charles L Dulberger, Sydney Stanley, Sean Wilson, Bree B Aldridge

Science· December 2022

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Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements.
Jonah Larkins-Ford, Yonatan N Degefu, Nhi Van, Artem Sokolov, Bree B Aldridge

Cell Rep Med· September 2022

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C25-modified rifamycin derivatives with improved activity against .
Laura Paulowski, Katherine S H Beckham, Matt D Johansen, Laura Berneking, Nhi Van, Bree B Aldridge

PNAS Nexus· September 2022

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Localization of EccA at the growing pole in Mycobacterium smegmatis.
Nastassja L Kriel, Mae Newton-Foot, Owen T Bennion, Bree B Aldridge, Carolina Mehaffy

BMC Microbiol· May 2022

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